STRINGSTRING
CEPR1 CEPR1 TDR TDR GSO2 GSO2 PEPR2 PEPR2 CLE9 CLE9 CDC73 CDC73 IKU2 IKU2 PSK1 PSK1 PEP1 PEP1 MBM17.3 MBM17.3 F20D23.7 F20D23.7 PEPR1 PEPR1 CLV1 CLV1 CLV3 CLV3 PSKR1 PSKR1 PXL1 PXL1 CRP4 CRP4 A8MS80_ARATH A8MS80_ARATH GSO1 GSO1 RGI3 RGI3 RLK7 RLK7 MDA7.8 MDA7.8 F25I18.9 F25I18.9 PSY1 PSY1 RLK5 RLK5 RGF1 RGF1 TPST TPST CLE10 CLE10 SERK1 SERK1 BAK1 BAK1 PSY1R PSY1R CEPR2 CEPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CEPR1Receptor protein-tyrosine kinase CEPR1; Receptor kinase involved in the perception of C-terminally encoded plant signaling peptide (CEP) and subsequent regulation of root and shoot development. Required for xylem and phloem cell files morphology and organization, probably by preventing ectopic lignification in phloem cells. Together with CEPR2, mediates systemic nitrogen (N)-demand signaling upon the perception of root-derived peptides (e.g. CEP1) via the up-regulation of genes involved in N uptake and assimilation pathways. Regulates positively lateral root initiation and development; [...] (966 aa)
TDRLeucine-rich repeat receptor-like protein kinase TDR; Acts with CLE41p and CLE44p peptides as a ligand-receptor pair in a signal transduction pathway involved in the regulation of procambium maintenance and polarity during vascular-tissue development. Mediates repression of tracheary element differentiation and the promotion of procambial cells formation and polar division adjacent to phloem cells in the veins; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1041 aa)
GSO2LRR receptor-like serine/threonine-protein kinase GSO2; Together with GSO1, receptor-like serine/threonine-kinase required during the development of the epidermal surface in embryos and cotyledons. Involved in the nuclear division phase of megagametogenesis. In coordination with GSO2, regulates root growth through control of cell division and cell fate specification. Controls seedling root growth by modulating sucrose response after germination. Receptor of the peptide hormones CIF1 and CIF2 required for contiguous Casparian strip diffusion barrier formation in roots. Belongs to the pr [...] (1252 aa)
PEPR2Leucine-rich repeat receptor-like protein kinase PEPR2; Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP- inducible plant responses (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1088 aa)
CLE9CLAVATA3/ESR (CLE)-related protein 9; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (120 aa)
CDC73Protein CDC73 homolog; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS- box genes of the MAF family. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. (415 aa)
IKU2Receptor-like protein kinase HAIKU2; Modulates the seed size by negatively regulating the cellularization of syncytial endosperm; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (991 aa)
PSK1Phytosulfokine-alpha; Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation. (87 aa)
PEP1Elicitor peptide 1; Elicitor of plant defense. Induces the production of plant defensin (PDF1.2) and of H(2)O(2). Promotes resistance to the root fungal pathogen P.irregulare. (92 aa)
MBM17.3Probable leucine-rich repeat receptor-like protein kinase At5g63930; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1102 aa)
F20D23.7Leucine-rich repeat receptor-like serine/threonine-protein kinase At1g17230; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1101 aa)
PEPR1Leucine-rich repeat receptor-like protein kinase PEPR1; Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates pathogen-associated molecular pattern (PAMP)-inducible plant responses. Involved in PAMP-triggered immunity (PTI) signaling. Interacts with and phosphorylates the kinase BIK1, a central rate-limiting kinase in PTI signaling. (1123 aa)
CLV1Receptor protein kinase CLAVATA1; Involved in the detection of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3p as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (980 aa)
CLV3Protein CLAVATA 3; Extracellular signal that regulates meristem maintenance. Acts with CLV1 as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the CLV3/ESR signal peptide family. (96 aa)
PSKR1Phytosulfokine receptor 1; Phytosulfokine receptor with both a serine/threonine-protein kinase activity and a guanylate cyclase activity. Regulates, in response to phytosulfokine binding, a signaling cascade involved in plant cell differentiation, organogenesis, somatic embryogenesis, cellular proliferation and plant growth. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Not involved in PSY perception. CNGC17 and AHAs form a functional cation-translocating unit that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (1008 aa)
PXL1Leucine-rich repeat receptor-like protein kinase PXL1; Involved in the regulation of procambium maintenance and polarity during vascular-tissue development. Phosphorylates HIRD11 and LHCA1 in vitro. (1029 aa)
CRP4ECA1 gametogenesis related family protein. (122 aa)
A8MS80_ARATHECA1 gametogenesis related family protein. (119 aa)
GSO1LRR receptor-like serine/threonine-protein kinase GSO1; Together with GSO2, receptor-like serine/threonine-kinase required during the development of the epidermal surface in embryos and cotyledons. In coordination with GSO2, regulates root growth through control of cell division and cell fate specification. Controls seedling root growth by modulating sucrose response after germination. Receptor of the peptide hormones CIF1 and CIF2 required for contiguous Casparian strip diffusion barrier formation in roots. Required for localizing CASP proteins into the Casparian strip following an un [...] (1249 aa)
RGI3LRR receptor-like serine/threonine-protein kinase; Acts as receptor of RGF1, a peptide hormone that maintains the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT). Links RGF1 signal with its downstream components. (1091 aa)
RLK7Receptor-like protein kinase 7; Plays a role in pattern-triggered immunity (PTI) signaling induced by pathogen-associated molecular patterns (PAMPs). Acts as a receptor for PIP1 defense peptide. PIP1 is an endogenous secreted peptide that acts as elicitor of immune response and positive regulator of defense response. Involved in the control of seed germination speed, in tolerance to oxidative stress and in maintaining seed longevity. (977 aa)
MDA7.8Leucine-rich receptor-like protein kinase family protein; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1090 aa)
F25I18.9Probable leucine-rich repeat receptor-like protein kinase At2g33170. (1124 aa)
PSY1Phytoene synthase, chloroplastic; Catalyzes the reaction from prephytoene diphosphate to phytoene; Belongs to the phytoene/squalene synthase family. (422 aa)
RLK5Receptor-like protein kinase 5; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates that controls floral organ abscission. May interact with the 'INFLORESCENCE DEFICIENT IN ABSCISSION' (IDA) ligands family. (999 aa)
RGF1Root meristem growth factor 1; Maintains the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT), mainly at the post-transcriptional level. Belongs to the RGF family. (116 aa)
TPSTProtein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. (500 aa)
CLE10CLAVATA3/ESR (CLE)-related protein 10; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (107 aa)
SERK1Somatic embryogenesis receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. (625 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
PSY1RTyrosine-sulfated glycopeptide receptor 1; Tyrosine-sulfated glycopeptide receptor with a serine/threonine-protein kinase activity. Regulates, in response to tyrosine-sulfated glycopeptide binding, a signaling cascade involved in cellular proliferation and plant growth. Not involved in PSK perception. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Mediates activation of the plasma membrane H(+)- ATPase by PSY1. Phosphorylates AHA2 at Thr-881. (1095 aa)
CEPR2Receptor protein-tyrosine kinase CEPR2; Receptor kinase involved in the perception of C-terminally encoded plant signaling peptide (CEP) and subsequent regulation of root and shoot development. Together with CEPR1, mediates systemic nitrogen (N)-demand signaling upon the perception of root-derived peptides (e.g. CEP1) via the up-regulation of genes involved in N uptake and assimilation pathways. (977 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.