7 items (Arabidopsis thaliana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CATHB2	Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...] (362 aa)
	CATHB3	Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...] (359 aa)
	F4N2.8	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family. (375 aa)
	CATHB1	Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...] (379 aa)
	F1N20.150	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family. (354 aa)
	HMGB1	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family. (178 aa)
	HMGB2	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses. (144 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CATHB1	F1N20.150	F4HVZ1	F4JKD9	Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.821
CATHB1	F4N2.8	F4HVZ1	Q9LQA9	Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.837
CATHB2	F1N20.150	Q93VC9	F4JKD9	Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.815
CATHB2	F4N2.8	Q93VC9	Q9LQA9	Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.824
CATHB3	F1N20.150	Q94K85	F4JKD9	Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.814
CATHB3	F4N2.8	Q94K85	Q9LQA9	Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...]	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.815
F1N20.150	CATHB1	F4JKD9	F4HVZ1	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	0.821
F1N20.150	CATHB2	F4JKD9	Q93VC9	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	0.815
F1N20.150	CATHB3	F4JKD9	Q94K85	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...]	0.814
F1N20.150	HMGB1	F4JKD9	O49595	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	0.410
F1N20.150	HMGB2	F4JKD9	O49596	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	0.497
F4N2.8	CATHB1	Q9LQA9	F4HVZ1	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 1; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB2 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	0.837
F4N2.8	CATHB2	Q9LQA9	Q93VC9	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 2; Thiol protease that plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD. Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD. Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD). Participates to the establishment of basal resistance against the bacterial pathogen Pseudomonase syri [...]	0.824
F4N2.8	CATHB3	Q9LQA9	Q94K85	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	Cathepsin B-like protease 3; Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC). Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp- Glu-Val-Asp-rhodamine 110 (DEVD-R110). Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase- 1 substrate YVAD-AMC. Plays a central role in plant programmed cell death (PCD). In addition to its role in protein degradation, may cleave and/or degrade a nu [...]	0.815
F4N2.8	HMGB1	Q9LQA9	O49595	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	0.435
F4N2.8	HMGB2	Q9LQA9	O49596	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	0.540
HMGB1	F1N20.150	O49595	F4JKD9	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.410
HMGB1	F4N2.8	O49595	Q9LQA9	High mobility group B protein 1; Binds preferentially double-stranded DNA. Modulates general plant growth and stress tolerance. Confers sensitivity to salt and genotoxic (methyl methanesulfonate, MMS) stresses. Belongs to the HMGB family.	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.435
HMGB2	F1N20.150	O49596	F4JKD9	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.497
HMGB2	F4N2.8	O49596	Q9LQA9	High mobility group B protein 2; Binds preferentially double-stranded DNA. Confers sensitivity to salt and drought stresses.	Eukaryotic aspartyl protease family protein; Belongs to the peptidase A1 family.	0.540