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NIFU3 NIFU3 CYP708A1 CYP708A1 CYP724A1 CYP724A1 CYP722A1 CYP722A1 CSL1 CSL1 CYP79C1 CYP79C1 CYP704A1 CYP704A1 CYP76G1 CYP76G1 CYP706A1 CYP706A1 CYP715A1 CYP715A1 CYP96A1 CYP96A1 CYP712A1 CYP712A1 PME12 PME12 CAD5 CAD5 psbC psbC SULTR2;2 SULTR2;2 CAD8 CAD8 CPK1 CPK1 TRM4 TRM4 CYP702A1 CYP702A1 GN GN TIR1 TIR1 CYP82F1 CYP82F1 BEE3 BEE3 PLT6 PLT6 PHF1 PHF1 CYP81G1 CYP81G1 BZR1 BZR1 PIF4 PIF4 TRM20 TRM20 GORK GORK AIR12 AIR12 OMT1 OMT1 MRG7.10 MRG7.10 LHT1 LHT1 CYP93D1 CYP93D1 CYP721A1 CYP721A1 CYP86C1 CYP86C1 BZR2 BZR2 CYP94D1 CYP94D1 CYP81K1 CYP81K1 SKOR SKOR CPK10 CPK10 TAA1 TAA1 CYP77B1 CYP77B1 RBOHB RBOHB RGP1 RGP1 C7A10.50 C7A10.50 YUC1 YUC1 YAB3 YAB3 CRK11 CRK11
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NIFU3NifU-like protein 3, chloroplastic; Molecular scaffold for [Fe-S] cluster assembly of chloroplastic iron-sulfur proteins; Belongs to the NifU family. (236 aa)
CYP708A1Cytochrome P450 family protein; Belongs to the cytochrome P450 family. (504 aa)
CYP724A1Cytochrome P450, family 724, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (421 aa)
CYP722A1Cytochrome P450, family 722, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (476 aa)
CSL1Disease resistance protein (TIR class). (808 aa)
CYP79C1Cytochrome P450, family 79, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (546 aa)
CYP704A1Cytochrome P450, family 704, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
CYP76G1Cytochrome P450, family 76, subfamily G, polypeptide 1; Belongs to the cytochrome P450 family. (530 aa)
CYP706A1Cytochrome P450, family 706, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (557 aa)
CYP715A1Cytochrome P450, family 715, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
CYP96A1Cytochrome P450, family 96, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (516 aa)
CYP712A1Cytochrome P450, family 712, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (514 aa)
PME12Probable pectinesterase/pectinesterase inhibitor 12; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family. (547 aa)
CAD5Cinnamyl alcohol dehydrogenase 5; Involved in lignin biosynthesis in the floral stem. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5- hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols. (357 aa)
psbCPhotosystem II CP43 reaction center protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbC subfamily. (473 aa)
SULTR2;2Sulfate transporter 2.2; Low-affinity H(+)/sulfate cotransporter that may be involved in the distribution of sulfate from vascular bundles to the palisade cells of the leaves. Plays a central role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (677 aa)
CAD8Cinnamyl alcohol dehydrogenase 8; Involved in lignin biosynthesis. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH- dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols. (359 aa)
CPK1Calcium-dependent protein kinase 1; May play a role in signal transduction pathways that involve calcium as a second messenger. Phosphorylates the Ca(2+)-ATPase ACA2 resulting in the inhibition of its calcium activation. (610 aa)
TRM4LONGIFOLIA protein. (1025 aa)
CYP702A1Cytochrome P450, family 702, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (482 aa)
GNARF guanine-nucleotide exchange factor GNOM; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of endosomal vesicle trafficking but is also involved in the endocytosis process. Could function redundantly with GNL1 in the retrograde Golgi to endoplasmic reticulum trafficking. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the sorting of PIN1 from endosomal compartments to the basal pla [...] (1451 aa)
TIR1Protein TRANSPORT INHIBITOR RESPONSE 1; Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. The SCF(TIR1) E3 ubiquitin ligase complex is involved in auxin-mediated signaling pathway that regulate root and hypocotyl growth, lateral root formation, cell elongation, and gravitropism. Appears to allow pericycle cells to overcome G2 arrest prior to lateral root development. Plays a role in ethylene signaling in roots. Confers sensitivity to the virulent bacterial pathogen P.syringae. (594 aa)
CYP82F1Cytochrome P450, family 82, subfamily F, polypeptide 1; Belongs to the cytochrome P450 family. (527 aa)
BEE3Transcription factor BEE 3; Positive regulator of brassinosteroid signaling. (261 aa)
PLT6Probable polyol transporter 6; Plasma membrane sugar-proton symporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (493 aa)
PHF1SEC12-like protein 1; Involved in Pi uptake by facilitating the trafficking of PHT1-1/PHT1;1 from the endoplasmic reticulum to the plasma membrane. (398 aa)
CYP81G1Cytochrome P450, family 81, subfamily G, polypeptide 1; Belongs to the cytochrome P450 family. (507 aa)
BZR1Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). (336 aa)
PIF4Transcription factor PIF4; Transcription factor acting negatively in the phytochrome B signaling pathway. May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif (By similarity). Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light). Belongs to the bHLH protein family. (430 aa)
TRM20Methyl-coenzyme M reductase II subunit gamma, putative (DUF3741). (924 aa)
GORKPotassium channel GORK; Major selective outward-rectifying potassium channel of the guard cell membrane. Involved in regulation of stomatal movements according to the water status. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. Conductance of the channel is modulated in a potassium-dependent fashion. May interact with the cytoskeleton or with regulatory proteins. (820 aa)
AIR12Auxin-induced in root cultures protein 12; One-heme-containing cytochrome. (252 aa)
OMT1Flavone 3'-O-methyltransferase 1; Methylates OH residues of flavonoid compounds. Converts quercetin into isorhamnetin. Dihydroquercetin is not a substrate. Catalyzes the methylation of monolignols, the lignin precursors. Does not contribute to the phenylpropanoid pattern of the pollen tryphine, but is probably confined to isorhamnetin glycoside biosynthesis. Involved in melatonin biosynthesis. Can function as acetylserotonin O- methyltransferase. Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I- [...] (363 aa)
MRG7.10Chaperone DnaJ-domain superfamily protein. (333 aa)
LHT1Lysine histidine transporter 1; Amino acid-proton symporter. Transporter with a broad specificity for histidine, lysine, glutamic acid, alanine, serine, proline and glycine. Involved in both apoplastic transport of amino acids in leaves and their uptake by roots. Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily. (446 aa)
CYP93D1Cytochrome P450, family 93, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family. (507 aa)
CYP721A1Cytochrome P450, family 721, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (505 aa)
CYP86C1Cytochrome P450, family 86, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (522 aa)
BZR2Protein BRASSINAZOLE-RESISTANT 2; Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N- terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C- terminal domain is probably involved in transcriptional activation. Recruits the transcription elongation factor IWS1 to control BR- regulated gene expression. Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-reg [...] (335 aa)
CYP94D1Cytochrome P450, family 94, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family. (498 aa)
CYP81K1Cytochrome P450, family 81, subfamily K, polypeptide 1; Belongs to the cytochrome P450 family. (500 aa)
SKORPotassium channel SKOR; Highly selective outward-rectifying potassium channel. Involved in potassium release into the xylem sap toward the shoots. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. The voltage-dependence of the channel is abolished by internal or external acidification. May interact with the cytoskeleton or with regulatory proteins; Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily. (828 aa)
CPK10Calcium-dependent protein kinase 10; May play a role in signal transduction pathways that involve calcium as a second messenger. May be a positive regulator controlling stress signal transduction. (545 aa)
TAA1L-tryptophan--pyruvate aminotransferase 1; L-tryptophan aminotransferase involved in auxin (IAA) biosynthesis. Can convert L-tryptophan and pyruvate to indole-3-pyruvic acid (IPA) and alanine. Catalyzes the first step in IPA branch of the auxin biosynthetic pathway. Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues. It is also active with phenylalanine, tyrosine, leucine, alanine, methionine and glutamine. Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are requ [...] (391 aa)
CYP77B1Cytochrome P450, family 77, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (510 aa)
RBOHBRespiratory burst oxidase homolog protein B; Calcium-dependent NADPH oxidase that generates superoxide; Belongs to the RBOH (TC 5.B.1.3) family. (843 aa)
RGP1UDP-arabinopyranose mutase 1; UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides. Catalyzes the interconvertion of UDP-L-arabinopyranose (UDP-Arap) and UDP-L-arabinofuranose (UDP-Araf) in vitro. Preferentially catalyzes the formation of UDP-Arap from UDP- Araf. At thermodynamic equilibrium in vitro the ratio of the pyranose form over the furanose form is 95:5. Is not active on other UDP-sugars (UDP-Gal, UDP-Xyl, UDP-Glc, GDP-Man and GDP-Fuc). Functions redundantly with RGP2 and is essential for proper cell walls and pollen development. Proba [...] (357 aa)
C7A10.50Cytochrome P450, family 81, subfamily H, polypeptide 1; Belongs to the cytochrome P450 family. (518 aa)
YUC1Probable indole-3-pyruvate monooxygenase YUCCA1; Involved in auxin biosynthesis, but not in the tryptamine or the CYP79B2/B3 branches. Catalyzes in vitro the N-oxidation of tryptamine to form N-hydroxyl tryptamine. Involved during embryogenesis and seedling development. Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (414 aa)
YAB3Axial regulator YABBY 3; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development. Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems. Binds DNA without sequence specificity. Belongs to the YABBY family. (240 aa)
CRK11Cysteine-rich receptor-like protein kinase 11. (667 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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