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RD22 RD22 PXG3 PXG3 MKK4 MKK4 DREB2A DREB2A CLPD CLPD DREB1B DREB1B RD29A RD29A NAC002 NAC002 Atmyb2 Atmyb2 MYC2 MYC2 SIZ1 SIZ1 HOS1 HOS1 NAC072 NAC072 WRKY18 WRKY18 NAC019 NAC019 BZIP8 BZIP8 DREB1D DREB1D NAC055 NAC055 SCRM SCRM MYB15 MYB15 DREB1A DREB1A ABF4 ABF4 ABF3 ABF3 ABF2 ABF2 ABF1 ABF1 DRIP1 DRIP1 WRKY40 WRKY40 ZHD11 ZHD11 F22C12.10 F22C12.10 WRKY60 WRKY60 DREB1C DREB1C
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RD22BURP domain protein RD22; Acts to suppress chlorophyll degradation under moisture stress. (392 aa)
PXG3Probable peroxygenase 3; Probable calcium-binding peroxygenase. May be involved in the degradation of storage lipid in oil bodies, in abiotic stress-related signaling pathway and in drought tolerance through stomatal control under water deficit conditions. (236 aa)
MKK4Mitogen-activated protein kinase kinase 4; Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the [...] (366 aa)
DREB2ADehydration-responsive element-binding protein 2A; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Belongs to the AP2/ERF transcription factor family. ERF subfamily. (335 aa)
CLPDChaperone protein ClpD, chloroplastic; Molecular chaperone that interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. The ATPase activity of CLPD is stimulated by CLPT1. Has no ADPase activity. Interacts with transit peptides with a positional preference. Localization of the signal sequence at the N-terminal end of a protein seems mandatory for interaction to take place ; Belongs to the ClpA/ClpB family. ClpD subfamily. (945 aa)
DREB1BDehydration-responsive element-binding protein 1B; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation; Belongs to the AP2/ERF transcription factor family. ERF subfamily. (213 aa)
RD29ALow-temperature-induced 78 kDa protein; Involved in responses to abiotic stresses. Regulates probably root elongation in cold conditions ; Belongs to the LTI78/LTI65 family. (710 aa)
NAC002NAC domain-containing protein 2. (289 aa)
Atmyb2MYB transcription factor (Atmyb2). (273 aa)
MYC2Transcription factor MYC2; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the prom [...] (623 aa)
SIZ1E3 SUMO-protein ligase SIZ1; E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance. Involved in freezing [...] (884 aa)
HOS1E3 ubiquitin-protein ligase HOS1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways. Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels. (927 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
WRKY18WRKY transcription factor 18; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. Positively modulates defense-related gene expression and disease resistance; Belongs to the WRKY group II-a family. (310 aa)
NAC019NAC domain-containing protein 19; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
DREB1DDehydration-responsive element-binding protein 1D; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates abscisic acid- and dehydration-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation. (224 aa)
NAC055NAC domain-containing protein 55; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
SCRMTranscription factor ICE1; Transcriptional activator that regulates the cold-induced transcription of CBF/DREB1 genes. Binds specifically to the MYC recognition sites (5'-CANNTG-3') found in the CBF3/DREB1A promoter. Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation. (494 aa)
MYB15Transcription factor MYB15; Transcription factor involved in cold-regulation of CBF genes and in the development of freezing tolerance. May be part of a complex network of transcription factors controlling the expression of CBF genes and other genes in response to cold stress. Binds to the MYB recognition sequences in the promoters of CBF1, CBF2 and CBF3 genes. Involved in drought and salt tolerance. May enhance expression levels of genes involved in abscisic acid (ABA) biosynthesis and signaling, as well as those encoding stress-protective proteins. (285 aa)
DREB1ADehydration-responsive element-binding protein 1A; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation; Belongs to the AP2/ERF transcription factor family. ERF subfamily. (216 aa)
ABF4ABSCISIC ACID-INSENSITIVE 5-like protein 7; Functions as transcriptional activator in the ABA-inducible expression of rd29B. Binds specifically to the ABA-responsive element (ABRE) of the rd29B gene promoter. (431 aa)
ABF3ABSCISIC ACID-INSENSITIVE 5-like protein 6; Binds to the ABA-responsive element (ABRE). Mediates stress- responsive ABA signaling; Belongs to the bZIP family. ABI5 subfamily. (454 aa)
ABF2ABSCISIC ACID-INSENSITIVE 5-like protein 5; Involved in ABA and stress responses and acts as a positive component of glucose signal transduction. Functions as transcriptional activator in the ABA-inducible expression of rd29B. Binds specifically to the ABA-responsive element (ABRE) of the rd29B gene promoter. (416 aa)
ABF1ABSCISIC ACID-INSENSITIVE 5-like protein 4; Binds to the ABA-responsive element (ABRE). Could participate in abscisic acid-regulated gene expression; Belongs to the bZIP family. ABI5 subfamily. (392 aa)
DRIP1E3 ubiquitin protein ligase DRIP1; E3 ubiquitin-protein ligase that acts as a negative regulator of the response to water stress. Mediates ubiquitination and subsequent proteasomal degradation of the drought-induced transcriptional activator DREB2A. Functionally redundant with DRIP2. (421 aa)
WRKY40Probable WRKY transcription factor 40; Transcription factor (By similarity). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor- responsive cis-acting element (By similarity). (302 aa)
ZHD11Zinc-finger homeodomain protein 11; Transcription factor involved in the up-regulation of several stress-inducible genes. Acts as a transcriptional activator by interacting with MED25 and NAC proteins. Involved in increased drought tolerance. (242 aa)
F22C12.10WRKY transcription factor. (646 aa)
WRKY60Probable WRKY transcription factor 60; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). (271 aa)
DREB1CDehydration-responsive element-binding protein 1C; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation; Belongs to the AP2/ERF transcription factor family. ERF subfamily. (216 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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