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ROPGEF5 ROPGEF5 IQD6 IQD6 ARAC7 ARAC7 ARAC10 ARAC10 CAM1 CAM1 CAM2 CAM2 CML10 CML10 IAA1 IAA1 RPS5B RPS5B CAM7 CAM7 CAM6 CAM6 NPY5 NPY5 IQD7 IQD7 IAA9 IAA9 IAA12 IAA12 TIR1 TIR1 NUP54 NUP54 FLA12 FLA12 PIN4 PIN4 AUX1 AUX1 Iqd8 Iqd8 CP1 CP1 BHLH32 BHLH32 AFB5 AFB5 AFB2 AFB2 XTH19 XTH19 T16L24.240 T16L24.240 IAA30 IAA30 IQD18 IQD18 HTH HTH LAX2 LAX2 TTM3 TTM3 PME44 PME44 CEL2 CEL2 NIP5-1 NIP5-1 YUC8 YUC8 YUC1 YUC1 GATA20 GATA20 RPS5A RPS5A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ROPGEF5Rop guanine nucleotide exchange factor 5; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. (611 aa)
IQD6Putative SF16 protein (Helianthus annuus). (416 aa)
ARAC7Rac-like GTP-binding protein ARAC7; Acts as a negative regulator of abscisic acid (ABA) responses. (209 aa)
ARAC10Rac-like GTP-binding protein ARAC10; Involved in local disassembly of cortical microtubules when associated with ICR5 and KIN13A; Belongs to the small GTPase superfamily. Rho family. (215 aa)
CAM1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CML10Calmodulin-like protein 10; Potential calcium sensor. (191 aa)
IAA1Auxin-responsive protein IAA1; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (168 aa)
RPS5B40S ribosomal protein S5-2; Belongs to the universal ribosomal protein uS7 family. (207 aa)
CAM7Calmodulin-7; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Activates MPK8 in vitro. (149 aa)
CAM6Calmodulin-6; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
NPY5BTB/POZ domain-containing protein NPY5; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play an essential role in auxin-mediated organogenesis and in root gravitropic responses; Belongs to the NPH3 family. (580 aa)
IQD7Calmodulin binding protein IQD7. (371 aa)
IAA9Auxin-responsive protein IAA9; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (338 aa)
IAA12Auxin-responsive protein IAA12; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (239 aa)
TIR1Protein TRANSPORT INHIBITOR RESPONSE 1; Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. The SCF(TIR1) E3 ubiquitin ligase complex is involved in auxin-mediated signaling pathway that regulate root and hypocotyl growth, lateral root formation, cell elongation, and gravitropism. Appears to allow pericycle cells to overcome G2 arrest prior to lateral root development. Plays a role in ethylene signaling in roots. Confers sensitivity to the virulent bacterial pathogen P.syringae. (594 aa)
NUP54Nuclear pore complex protein NUP54. (377 aa)
FLA12Fasciclin-like arabinogalactan protein 12; May be a cell surface adhesion protein; Belongs to the fasciclin-like AGP family. (249 aa)
PIN4Auxin efflux carrier component 4; Acts as a component of the auxin efflux carrier. Plays a role in generating a sink for auxin into columella cells. Maintains the endogenous auxin gradient, which is essential for correct root patterning. Involved in EXO70A3-regulated gravitropic responses in columella cells and in root system architecture (RSA). (616 aa)
AUX1Auxin transporter protein 1; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files. Coordinated subcellular localization of AUX1 is regula [...] (485 aa)
Iqd8IQ-domain 8. (414 aa)
CP1Calcium-binding protein CP1; Binds calcium in vitro. (160 aa)
BHLH32Transcription factor AIG1; Transcription factor required for MONOPTEROS-dependent root initiation in embryo. Transcriptionally controlled by MONOPTEROS. (344 aa)
AFB5Transport inhibitor response 1-like protein. (619 aa)
AFB2Protein AUXIN SIGNALING F-BOX 2; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Confers sensitivity to the virulent bacterial pathogen P.syringae (By similarity). Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin- regulated transcription. Involved in embryogenesis regulation by auxin. (575 aa)
XTH19Xyloglucan endotransglucosylase/hydrolase protein 19; Possesses xyloglucan endotransglucosylase (XET) activity in vitro. Does not possess xyloglucan endohydrolysis (XEH) activity. Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Involved in cell proliferation in the tissue reunion process of wounded inflorescence stems. Maybe a downstream target of NAC071 as a consequence of auxin action in wounded stems. (277 aa)
T16L24.240IQ-domain 13. (517 aa)
IAA30Auxin-responsive protein IAA30; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (172 aa)
IQD18IQ-domain 18. (527 aa)
HTHProtein HOTHEAD; Probable FAD-dependent enzyme. Involved in regulating post- genital organ fusion. Required to limit cellular interactions between contacting epidermal cells during floral development. (594 aa)
LAX2Auxin transporter-like protein 2; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex (By similarity); Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily. (483 aa)
TTM3Triphosphate tunnel metalloenzyme 3; Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside- linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity. (210 aa)
PME44Probable pectinesterase/pectinesterase inhibitor 44; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family. (525 aa)
CEL2Endoglucanase 1. (501 aa)
NIP5-1Probable aquaporin NIP5-1; Boric acid transporter. Low water transport activity. Plays an important role as plasma membrane boric acid channel for the boron uptake required for plant growth and development under boron limitation; Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily. (304 aa)
YUC8Probable indole-3-pyruvate monooxygenase YUCCA8; Involved in auxin biosynthesis. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in roots. (426 aa)
YUC1Probable indole-3-pyruvate monooxygenase YUCCA1; Involved in auxin biosynthesis, but not in the tryptamine or the CYP79B2/B3 branches. Catalyzes in vitro the N-oxidation of tryptamine to form N-hydroxyl tryptamine. Involved during embryogenesis and seedling development. Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (414 aa)
GATA20GATA transcription factor 20; Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters; Belongs to the type IV zinc-finger family. Class B subfamily. (208 aa)
RPS5A40S ribosomal protein S5-1. (207 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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