STRINGSTRING
MPK3 MPK3 DAA1 DAA1 SEP3 SEP3 UGT74F2 UGT74F2 GSTF9 GSTF9 AS1 AS1 CML20 CML20 CAM1 CAM1 CAM2 CAM2 CML24 CML24 CML12 CML12 CML10 CML10 COR47 COR47 ERD10 ERD10 P5CSA P5CSA CAM7 CAM7 ABI3 ABI3 CAM6 CAM6 LTI65 LTI65 RD29A RD29A RD22 RD22 MPK1 MPK1 MPK6 MPK6 Atmyb2 Atmyb2 CML41 CML41 MKK5 MKK5 MSRB7 MSRB7 NAC072 NAC072 EDL3 EDL3 CP1 CP1 T9L24.51 T9L24.51 RZPF34 RZPF34 SAG113 SAG113 CML37 CML37 FAMT FAMT PEPR2 PEPR2 AFP2 AFP2 SIS SIS CML9 CML9 MDAR3 MDAR3 CML38 CML38 CML39 CML39 RALF1 RALF1 GSTF7 GSTF7 CML36 CML36 CML42 CML42 KIC KIC MAPKKK18 MAPKKK18
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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MPK3Mitogen-activated protein kinase 3; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Mediates the phosphorylation of VIP1 and subsequent stress genes transcription in response to Agrobacterium. MKK9-M [...] (370 aa)
DAA1P-loop containing nucleoside triphosphate hydrolases superfamily protein. (829 aa)
SEP3Developmental protein SEPALLATA 3; Probable transcription factor active in inflorescence development and floral organogenesis. Functions with SEPALLATA1/AGL2 and SEPALLATA2/AGL4 to ensure proper development of petals, stamens and carpels and to prevent the indeterminate growth of the flower meristem. Interacts with APETALA1, AGAMOUS or APETALA3/PISTILLATA to form complexes, that could be involved in genes regulation during floral meristem development. Binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3'. (251 aa)
UGT74F2UDP-glycosyltransferase 74F2; Glycosyltransferase that glucosylates benzoic acid and derivatives. Substrate preference is benzoic acid > salicylic acid (SA) > 3-hydroxybenzoic acid > 4-hydroxybenzoic acid. Catalyzes the formation of both SA 2-O-beta-D-glucoside (SAG) and SA glucose ester (SGE). Has high affinity for the tryptophan precursor anthranilate. Catalyzes the formation of anthranilate glucose ester. Is the major source of this activity in the plant. (449 aa)
GSTF9Glutathione S-transferase F9; In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC), and glutathione peroxidase activity toward cumene hydroperoxide and linoleic acid-13-hydroperoxide. May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides. (215 aa)
AS1Transcription factor AS1; Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis. Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development. [...] (367 aa)
CML20Probable calcium-binding protein CML20; Potential calcium sensor. (169 aa)
CAM1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CML24Calcium-binding protein CML24; Calcium-binding protein that may positively regulate abscisic acid (ABA) inhibition of germination and seedling development. May be required for photoperiod-induced flowering and function in ion homeostasis. (161 aa)
CML12Calmodulin-like protein 12; Potential calcium sensor that binds calcium in vitro. (324 aa)
CML10Calmodulin-like protein 10; Potential calcium sensor. (191 aa)
COR47Dehydrin COR47. (265 aa)
ERD10Dehydrin ERD10. (260 aa)
P5CSADelta-1-pyrroline-5-carboxylate synthase A; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family. (717 aa)
CAM7Calmodulin-7; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Activates MPK8 in vitro. (149 aa)
ABI3B3 domain-containing transcription factor ABI3; Participates in abscisic acid-regulated gene expression during seed development. Regulates the transcription of SGR1 and SGR2 that are involved in leaf and embryo degreening. (720 aa)
CAM6Calmodulin-6; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
LTI65Low-temperature-induced 65 kDa protein; Belongs to the LTI78/LTI65 family. (619 aa)
RD29ALow-temperature-induced 78 kDa protein; Involved in responses to abiotic stresses. Regulates probably root elongation in cold conditions ; Belongs to the LTI78/LTI65 family. (710 aa)
RD22BURP domain protein RD22; Acts to suppress chlorophyll degradation under moisture stress. (392 aa)
MPK1Mitogen-activated protein kinase 1. (370 aa)
MPK6Mitogen-activated protein kinase 6; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Phosphorylates 1-aminocyclopropane-1- carboxylic acid synthases (ACS2 and ACS6) and may be involved in the regulati [...] (395 aa)
Atmyb2MYB transcription factor (Atmyb2). (273 aa)
CML41Probable calcium-binding protein CML41; Potential calcium sensor. (205 aa)
MKK5Mitogen-activated protein kinase kinase 5; Involved in the second phase of hydrogen peroxide generation during hypersensitive response-like cell death. Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. Activates by phosphorylation the downstream MPK3 and MPK6. YDA-MKK4/MKK5-MPK3/MPK6 module regulates stomatal cell fate before the guard mother cell (GMC) is specified. This MAPK cascade also functions downstream of the ER receptor in regulating coordinated local cell proliferation, which shapes the [...] (348 aa)
MSRB7Peptide methionine sulfoxide reductase B7; Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. MSRB family specifically reduces the MetSO R- enantiomer (By similarity). (144 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
EDL3EID1-like F-box protein 3. (272 aa)
CP1Calcium-binding protein CP1; Binds calcium in vitro. (160 aa)
T9L24.51Calmodulin-like protein. (254 aa)
RZPF34E3 ubiquitin-protein ligase RZFP34; Possesses E3 ubiquitin-protein ligase activity in vitro. Mediates mainly 'Lys-48'-linked polyubiquitination. Promotes abscisic acid (ABA)-induced stomatal closure, reactive oxygen species (ROS) production and drought tolerance. Involved in the regulation of stomatal aperture. (291 aa)
SAG113Probable protein phosphatase 2C 78; Acts as negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as negative regulator of osmotic stress and ABA signaling. Acts as negative regulator of response to drought. Belongs to the PP2C family. (413 aa)
CML37Calcium-binding protein CML37; Potential calcium sensor that binds calcium in vitro. (185 aa)
FAMTFarnesoic acid carboxyl-O-methyltransferase; May catalyze the production of the insect juvenile hormone methyl farnesoate (MeFA) to trigger defense against insect herbivory. Belongs to the methyltransferase superfamily. SABATH family. (348 aa)
PEPR2Leucine-rich repeat receptor-like protein kinase PEPR2; Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP- inducible plant responses (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1088 aa)
AFP2Ninja-family protein AFP2; Acts as a negative regulator of abscisic acid (ABA) response during germination through the ubiquitin-mediated proteolysis of ABI5/DPBF1. (348 aa)
SISE3 ubiquitin-protein ligase RLIM-like protein. (149 aa)
CML9Calmodulin-like protein 9; Potential calcium sensor. (151 aa)
MDAR3Monodehydroascorbate reductase 3; Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. Required for producing sufficient ascorbate to maintain the interaction between Piriformospora indica and Arabidopsis in a mutualistic state. (441 aa)
CML38Calcium-binding protein CML38; Potential calcium sensor that binds calcium in vitro. (177 aa)
CML39Calcium-binding protein CML39; Potential calcium sensor that binds calcium in vitro. (159 aa)
RALF1Protein RALF-like 1; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases. Mostly active in roots. Prevents plant growth (e.g. root and leaf length). Suppresses cell elongation of the primary root by activating the cell surface receptor FER and triggering phosphorylation [...] (120 aa)
GSTF7Glutathione S-transferase F7; May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides; Belongs to the GST superfamily. Phi family. (209 aa)
CML36Probable calcium-binding protein CML36; Potential calcium sensor. (209 aa)
CML42Calcium-binding protein CML42; Probable calcium sensor that binds calcium in vitro. Involved in the regulation of trichome branching. (191 aa)
KICCalcium-binding protein KIC; Calcium-binding regulatory protein that interacts with kinesin motor protein KCBP in a calcium-dependent manner. Inhibits KCBP microtubule binding activity and microtubule-stimulated ATPase activity. Involved in the regulation of trichome branching through its interaction with KCBP. (135 aa)
MAPKKK18Mitogen-activated protein kinase kinase kinase 18; Component of the abscisic acid (ABA) signaling pathway that acts as ABA signal transducer in the context of abiotic stresses. Triggers MPK1, MPK2, MPK7 and MPK14 activation in a MKK3-dependent manner and MPK6 activation in a MKK3-independent manner. Mediates the ABA-dependent activation of the MKK3-MPK7 module. Positive regulator of ABA responses leading to the induction of gene expression (e.g. RD29B and RAB18) and involved in various responses including stomatal development, stomatal movement, inhibition of germination and root growt [...] (339 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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