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BHLH104 BHLH104 B3H7M7_ARATH B3H7M7_ARATH BRI1 BRI1 UNE12 UNE12 MYC4 MYC4 BPE BPE BHLH18 BHLH18 SKP1A SKP1A BHLH72 BHLH72 BHLH74 BHLH74 BHLH157 BHLH157 PIF5 PIF5 BHLH11 BHLH11 PIF4 PIF4 CUL1 CUL1 BHLH115 BHLH115 BZIP8 BZIP8 BIM2 BIM2 MYC3 MYC3 BHLH92 BHLH92 BHLH99 BHLH99 BIM3 BIM3 GL3 GL3 BIM1 BIM1 BHLH77 BHLH77 BZR2 BZR2 BHLH13 BHLH13 BHLH93 BHLH93 BHLH34 BHLH34 ABCF4 ABCF4 ORG2 ORG2 MUTE MUTE BHLH47 BHLH47 AIB AIB BHLH66 BHLH66
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BHLH104Transcription factor bHLH104. (283 aa)
B3H7M7_ARATHCorepressor. (170 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
UNE12Transcription factor UNE12; Required for ovule fertilization. (310 aa)
MYC4Transcription factor MYC4; Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA- dependent responses. Can form complexes with all known glucosinolate- related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (589 aa)
BPETranscription factor BPE; Involved in the control of petal size, by interfering with postmitotic cell expansion to limit final petal cell size. (343 aa)
BHLH18Transcription factor bHLH18. (305 aa)
SKP1ASKP1-like protein 1A; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicate [...] (160 aa)
BHLH72Transcription factor PIF7; Transcription factor acting negatively in the phytochrome B signaling pathway under prolonged red light. Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin- proteasome pathway. May regulate the expression of a subset of genes by binding to the G-box motif. (366 aa)
BHLH74Transcription factor bHLH74; Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. (366 aa)
BHLH157Transcription factor bHLH157; Transcription factor that may regulate root development. (527 aa)
PIF5Transcription factor PIF5; Transcription factor acting negatively in the phytochrome B signaling pathway to promote the shade-avoidance response. Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin-proteasome pathway. Promotes ethylene activity in the dark. May regulate the expression of a subset of genes by binding to the G- box motif. Might be involved in the integration of light-signals to control both circadian and photomorphogenic processes. Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box var [...] (444 aa)
BHLH11Transcription factor bHLH11. (286 aa)
PIF4Transcription factor PIF4; Transcription factor acting negatively in the phytochrome B signaling pathway. May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif (By similarity). Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light). Belongs to the bHLH protein family. (430 aa)
CUL1Cullin-1; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1, RBX1 and a F-box protein, it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL), SCF(ADO2/LKP2), SCF(A [...] (738 aa)
BHLH115Transcription factor bHLH115. (226 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
BIM2Transcription factor BIM2; Positive brassinosteroid-signaling protein. (311 aa)
MYC3Transcription factor MYC3; Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (592 aa)
BHLH92Transcription factor bHLH92. (247 aa)
BHLH99Transcription factor bHLH99. (296 aa)
BIM3Transcription factor BIM3; Positive brassinosteroid-signaling protein. (298 aa)
GL3Transcription factor GLABRA 3; Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation, but, in association with TTG1 and MYB0/GL1, promotes trichome formation, branching and endoreplication. Regulates also trichome cell wall maturation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell form [...] (637 aa)
BIM1Transcription factor BIM1; Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. (529 aa)
BHLH77Transcription factor bHLH77. (371 aa)
BZR2Protein BRASSINAZOLE-RESISTANT 2; Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N- terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C- terminal domain is probably involved in transcriptional activation. Recruits the transcription elongation factor IWS1 to control BR- regulated gene expression. Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-reg [...] (335 aa)
BHLH13Transcription factor bHLH13. (590 aa)
BHLH93Transcription factor bHLH93; Transcription factor. May be involved in the differentiation of stomatal guard cells. (351 aa)
BHLH34Transcription factor bHLH34. (320 aa)
ABCF4ABC transporter F family member 4; Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily. (723 aa)
ORG2Transcription factor ORG2. (253 aa)
MUTETranscription factor MUTE; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. (202 aa)
BHLH47Transcription factor bHLH47. (240 aa)
AIBTranscription factor ABA-INDUCIBLE bHLH-TYPE; Transcription activator. Regulates positively abscisic acid (ABA) response. Confers drought tolerance and sensitivity to ABA. (566 aa)
BHLH66Transcription factor bHLH66. (350 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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