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atp6 atp6 nad1 nad1 nad5 nad5 nad2 nad2 cox2 cox2 ccmB ccmB rps7 rps7 nad9 nad9 ccmFC ccmFC nad6 nad6 nad4 nad4 mttB mttB rpl2 rpl2 nad3 nad3 ccmC ccmC rps12 rps12 nad7 nad7 matR matR nad4L nad4L atp4 atp4 ABCI5 ABCI5 rbcL rbcL ND2 ND2 ND5 ND5 RPS19 RPS19 RPS13 RPS13 RPL8A RPL8A accD accD psaA psaA psaB psaB psaI psaI psbC psbC cemA cemA ycf4 ycf4 rpl2-A rpl2-A rpl16 rpl16 rps14 rps14 rps19 rps19 ATP9 ATP9 ND6 ND6 COX1 COX1 rps7-A rps7-A rps12-A rps12-A CCMC CCMC RPS12 RPS12 ND3 ND3 RPS7 RPS7 ND1 ND1 CCMB CCMB COX2 COX2 CCMFC CCMFC NAD7 NAD7 RPL2 RPL2 ND4 ND4 ND4L ND4L atp9 atp9 RCD1 RCD1 RPS1 RPS1 SDH4 SDH4 RPL16 RPL16 NAD9 NAD9 RPS13-2 RPS13-2 RPL10 RPL10 rps14-2 rps14-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
atp6ATP synthase subunit a. (385 aa)
nad1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (325 aa)
nad5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (669 aa)
nad2NADH dehydrogenase subunit 2. (488 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
ccmBCytochrome c biogenesis B. (206 aa)
rps7Ribosomal protein S7. (148 aa)
nad9NADH dehydrogenase subunit 9; Belongs to the complex I 30 kDa subunit family. (190 aa)
ccmFCCytochrome c biogenesis FC. (442 aa)
nad6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (205 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
mttBTransport membrane protein. (280 aa)
rpl2Ribosomal protein L2. (349 aa)
nad3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
ccmCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
rps12Ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (125 aa)
nad7NADH dehydrogenase subunit 7; Belongs to the complex I 49 kDa subunit family. (394 aa)
matRMaturase. (656 aa)
nad4LNADH dehydrogenase subunit 4L. (100 aa)
atp4ATPase subunit 4. (192 aa)
ABCI5Putative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
rbcLRibulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (479 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (499 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (669 aa)
RPS1940S ribosomal protein S19, mitochondrial; The RNA-binding domain found in RPS19 may functionally replaces the missing mitochondrial RPS13; Belongs to the universal ribosomal protein uS19 family. (212 aa)
RPS1330S ribosomal protein S13, chloroplastic; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; Belongs to the universal ribosomal protein uS13 family. (169 aa)
RPL8A60S ribosomal protein L8-1. (258 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (488 aa)
psaAPhotosystem I P700 chlorophyll a apoprotein A1; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (750 aa)
psaBPhotosystem I P700 chlorophyll a apoprotein A2; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (734 aa)
psaIPhotosystem I reaction center subunit VIII; May help in the organization of the PsaL subunit. Belongs to the PsaI family. (37 aa)
psbCPhotosystem II CP43 reaction center protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbC subfamily. (473 aa)
cemAChloroplast envelope membrane protein; May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts. Belongs to the Cema family. (229 aa)
ycf4Photosystem I assembly protein Ycf4; Seems to be required for the assembly of the photosystem I complex; Belongs to the Ycf4 family. (184 aa)
rpl2-A50S ribosomal protein L2, chloroplastic; Belongs to the universal ribosomal protein uL2 family. (274 aa)
rpl1650S ribosomal protein L16, chloroplastic; Belongs to the universal ribosomal protein uL16 family. (135 aa)
rps1430S ribosomal protein S14, chloroplastic; Binds 16S rRNA, required for the assembly of 30S particles. Belongs to the universal ribosomal protein uS14 family. (100 aa)
rps1930S ribosomal protein S19, chloroplastic; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
ATP9ATP synthase subunit 9, mitochondrial; This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase. (85 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (205 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (527 aa)
rps7-A30S ribosomal protein S7, chloroplastic; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. (155 aa)
rps12-A30S ribosomal protein S12, chloroplastic; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity). (123 aa)
CCMCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (232 aa)
RPS12Ribosomal protein S12, mitochondrial; Protein S12 is involved in the translation initiation step; Belongs to the universal ribosomal protein uS12 family. (125 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (119 aa)
RPS7Ribosomal protein S7, mitochondrial; One of the primary rRNA binding proteins, it binds directly to 18S rRNA where it nucleates assembly of the head domain of the small subunit; Belongs to the universal ribosomal protein uS7 family. (148 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (325 aa)
CCMBPutative cytochrome c biogenesis ccmB-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. (206 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
CCMFCCytochrome c biogenesis CcmF C-terminal-like mitochondrial protein; Forms a complex with CCMFN1, CCMFN2 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria. Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. (442 aa)
NAD7NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. (394 aa)
RPL260S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (349 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (100 aa)
atp9ATP synthase subunit 9, mitochondrial; Belongs to the ATPase C chain family. (85 aa)
RCD1Inactive poly [ADP-ribose] polymerase RCD1; Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses. Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses. May regulate several stress-responsive genes. Seems to play a larger developmental role than SRO1. Does not bind NAD in vitro. (589 aa)
RPS130S ribosomal protein S1, chloroplastic; Required for optimal plastid performance in terms of photosynthesis and growth. Required for the translation of plastid mRNAs. Involved in cellular heat stress response and required for heat tolerance. Required for transcriptional activation of HSFA2 and its target genes in response to heat stress. Plays a critical role in biosynthesis of thylakoid membrane proteins encoded by chloroplast genes. (416 aa)
SDH4Succinate dehydrogenase subunit 4, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (151 aa)
RPL1660S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. (179 aa)
NAD9NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (190 aa)
RPS13-2Small ribosomal subunit protein S13, mitochondrial; Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA. (154 aa)
RPL1050S ribosomal protein L10, chloroplastic; This protein binds directly to 23S ribosomal RNA. (220 aa)
rps14-2Mitochondrial ribosomal protein S14. (164 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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