STRINGSTRING
E2FA E2FA TOR TOR E2FB E2FB CBSX3 CBSX3 CBSCBSPB3 CBSCBSPB3 CBSDUFCH1 CBSDUFCH1 ABCF4 ABCF4 SETH3 SETH3 CBSCBSPB2 CBSCBSPB2 PV42A PV42A CBSPPR1 CBSPPR1 MGN6.11 MGN6.11 CBSX1 CBSX1 CBSCBSPB5 CBSCBSPB5 A1 A1 CLC-G CLC-G CLC-A CLC-A CLC-B CLC-B CLC-D CLC-D CBSCBSPB4 CBSCBSPB4 ARAC4 ARAC4 CBSDUF1 CBSDUF1 CBSX5 CBSX5 CLC-E CLC-E PV42B PV42B CBSX6 CBSX6 KING1 KING1 CLC-F CLC-F SNF4 SNF4 CLC-C CLC-C CBSX2 CBSX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2FATranscription factor E2FA; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. Belongs to the E2F/DP family. (485 aa)
TORSerine/threonine-protein kinase TOR; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic [...] (2481 aa)
E2FBTranscription factor E2FB; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. (469 aa)
CBSX3CBS domain-containing protein CBSX3, mitochondrial. (206 aa)
CBSCBSPB3CBS domain-containing protein CBSCBSPB3. (556 aa)
CBSDUFCH1Putative DUF21 domain-containing protein At3g13070, chloroplastic. (661 aa)
ABCF4ABC transporter F family member 4; Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily. (723 aa)
SETH3Probable arabinose 5-phosphate isomerase; Catalyzes the reversible aldol-ketol isomerization between D- ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P). Belongs to the SIS family. GutQ/KpsF subfamily. (350 aa)
CBSCBSPB2CBS domain-containing protein CBSCBSPB2. (536 aa)
PV42ASNF1-related protein kinase regulatory subunit gamma-like PV42a; Plays redundant role with PV42b in regulating male gametogenesis and pollen tube guidance. (352 aa)
CBSPPR1Pentatricopeptide repeat-containing protein At5g10690; Belongs to the PPR family. P subfamily. (580 aa)
MGN6.11CBS domain-containing protein. (408 aa)
CBSX1CBS domain-containing protein CBSX1, chloroplastic. (236 aa)
CBSCBSPB5CBS domain-containing protein CBSCBSPB5. (548 aa)
A1Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (449 aa)
CLC-GPutative chloride channel-like protein CLC-g; Putative voltage-gated chloride channel. (765 aa)
CLC-AChloride channel protein CLC-a; Voltage-gated chloride channel that could play a role in the regulation of nitrate content. (775 aa)
CLC-BChloride channel protein CLC-b; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (780 aa)
CLC-DChloride channel protein CLC-d; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (792 aa)
CBSCBSPB4CBS domain-containing protein CBSCBSPB4. (548 aa)
ARAC4Rac-like GTP-binding protein ARAC4; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (By similarity). May be involved in cell polarity control during the actin-dependent tip growth of root hairs. May regulate a WAVE complex that activates the Arp2/3 complex. (195 aa)
CBSDUF1DUF21 domain-containing protein At4g14240. (494 aa)
CBSX5CBS domain-containing protein CBSX5. (391 aa)
CLC-EChloride channel protein CLC-e; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (710 aa)
PV42BSNF1-related protein kinase regulatory subunit gamma-like PV42b; Plays redundant role with PV42a in regulating male gametogenesis and pollen tube guidance. (357 aa)
CBSX6CBS domain-containing protein CBSX6. (425 aa)
KING1SNF1-related protein kinase regulatory subunit gamma-1; Regulatory subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase. (424 aa)
CLC-FChloride channel protein CLC-f; Voltage-gated chloride channel. (781 aa)
SNF4Sucrose nonfermenting 4-like protein; Regulatory subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. (487 aa)
CLC-CChloride channel protein CLC-c; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (779 aa)
CBSX2CBS domain-containing protein CBSX2, chloroplastic. (238 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (16%) [HD]