STRINGSTRING
F22D22.11 F22D22.11 SUS5 SUS5 MRA19.16 MRA19.16 APA1 APA1 GLX1 GLX1 GSA1 GSA1 RD19A RD19A SUS1 SUS1 SUS2 SUS2 CWINV2 CWINV2 PRF4 PRF4 PRF5 PRF5 BFRUCT4 BFRUCT4 PRF2 PRF2 PRF1 PRF1 GSA2 GSA2 BFRUCT3 BFRUCT3 CWINV1 CWINV1 CWINV3 CWINV3 RIN4 RIN4 ACS12 ACS12 T6D22.20 T6D22.20 F10B6.22 F10B6.22 CWINV4 CWINV4 PFP-BETA1 PFP-BETA1 CWINV6 CWINV6 F1N21.10 F1N21.10 PRF3 PRF3 NFXL2 NFXL2 PGD3 PGD3 RLK RLK DHAR2 DHAR2 PGD2 PGD2 DHAR1 DHAR1 SUS6 SUS6 F6I1.3 F6I1.3 HSP70-4 HSP70-4 CWINV5 CWINV5 ACS10 ACS10 SUS4 SUS4 SUS3 SUS3 F12M16.29 F12M16.29 PGD1 PGD1 PAT PAT PFP-ALPHA1 PFP-ALPHA1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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F22D22.11Transmembrane receptor. (353 aa)
SUS5Sucrose synthase 5; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (836 aa)
MRA19.16Ubiquitin domain-containing protein. (118 aa)
APA1Aspartic proteinase A1; Involved in the breakdown of propeptides of storage proteins in protein-storage vacuoles (By similarity). Possesses aspartic protease activity in vitro. (506 aa)
GLX1Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (283 aa)
GSA1Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; Transaminase converting glutamate 1-semialdehyde (GSA) to 5- aminolevulinate (ALA). Involved in the biosynthesis of tetrapyrroles. (474 aa)
RD19ACysteine protease RD19A; Probable thiol protease (By similarity). Required for RRS1- mediated resistance against Ralstonia solanacearum. Plays a crucial role as host factor for PopP2-triggered RRS1-mediated resistance. Interacts with the R.solanacearum type III effector PopP2 to form a nuclear complex that is required for activation of the RRS1-mediated resistance response ; Belongs to the peptidase C1 family. (368 aa)
SUS1Sucrose synthase 1; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
SUS2Sucrose synthase 2; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and directs carbon towards starch synthesis in developing seeds. (807 aa)
CWINV2Beta-fructofuranosidase, insoluble isoenzyme CWINV2. (590 aa)
PRF4Profilin-4; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF5 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
PRF5Profilin-5; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Acts redundantly with PRF4 to regulate apical actin polymerization at the tip of pollen tube and control polarized pollen tube growth. Functions probably by favoring formin-mediated actin polymerization at pollen tube tips. (134 aa)
BFRUCT4Acid beta-fructofuranosidase 4, vacuolar; Possible role in the continued mobilization of sucrose to sink organs. Regulates root elongation. (664 aa)
PRF2Profilin-2; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds G- actin and poly-L-proline with low affinity in vitro. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton. At high concentrations, profilin prevents the pol [...] (131 aa)
PRF1Profilin-1; Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. Coordinates the stochastic dynamic properties of actin filaments by modulating formin- mediated actin nucleation and assembly during axial cell expansion. Binds G-actin and poly-L-proline in vitro. Inhib [...] (131 aa)
GSA2Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; Transaminase converting glutamate 1-semialdehyde (GSA) to 5- aminolevulinate (ALA). Involved in the biosynthesis of tetrapyrroles. (472 aa)
BFRUCT3Acid beta-fructofuranosidase 3, vacuolar; Possible role in the continued mobilization of sucrose to sink organs. (648 aa)
CWINV1Beta-fructofuranosidase, insoluble isoenzyme CWINV1; Beta-fructofuranosidase that can use sucrose and 1-kestose, and, to a lower extent, neokestose and levan, as substrates, but not inuline; Belongs to the glycosyl hydrolase 32 family. (584 aa)
CWINV3Beta-fructofuranosidase, insoluble isoenzyme CWINV3; 6-fructan exohydrolase that can use phlein, levan, neokestose, levanbiose, 6-kestose, and 1-kestose as substrates. (594 aa)
RIN4RPM1-interacting protein 4; Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its associ [...] (211 aa)
ACS12Probable aminotransferase ACS12; Probable aminotransferase. Does not have 1-aminocyclopropane- 1-carboxylate synthase (ACS) activity, suggesting that it is not involved in ethylene biosynthesis. (495 aa)
T6D22.20Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
F10B6.22Aspartate-semialdehyde dehydrogenase, putative. (375 aa)
CWINV4Beta-fructofuranosidase, insoluble isoenzyme CWINV4. (591 aa)
PFP-BETA1Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1; Catalytic subunit of pyrophosphate--fructose 6-phosphate 1- phosphotransferase. Catalyzes the phosphorylation of D-fructose 6- phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP- dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-s [...] (566 aa)
CWINV6Beta-fructofuranosidase, insoluble isoenzyme CWINV6; 6 and 1-fructan exohydrolase that can degrade both inulin and levan-type fructans, such as phlein, levan, neokestose, levanbiose, 6- kestose, 1-kestose, inulin, and 1,1-nystose. (550 aa)
F1N21.10Probable lactoylglutathione lyase, chloroplastic; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (350 aa)
PRF3Profilin-3; Binds to actin monomers and regulates the organization of the actin cytoskeleton. Can increase the critical concentration (Cc) of actin assembly in vitro. Acts as downstream effector of the hydrogen sulfide signaling to regulate the assembly and depolymerization of F-actin. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (Probable). Binding to the poly-proline motif of formin induces oligomerization of PRF3. PRF3 oligomers inhibit formin-mediated actin assembly to modulate plant immunity triggered by pathog [...] (168 aa)
NFXL2NF-X1-type zinc finger protein NFXL2; Probable transcriptional regulator. May mediate E2- or E3- dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. P [...] (883 aa)
PGD36-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
RLKLeucine-rich repeat receptor-like protein kinase. (751 aa)
DHAR2Glutathione S-transferase DHAR2; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses. Plays a role in ozone tolerance; Belongs to the GST superfamily. DHAR family. (213 aa)
PGD26-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. Required for guided growth of the male gametophytes and interaction between the pollen tube and the ovule. (486 aa)
DHAR1Glutathione S-transferase DHAR1, mitochondrial; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses, subsequently to biotic or abiotic inducers. As a peripheral membrane protein, could also function as voltage-gated ion channel. Belongs to the GST superfamily. DHAR family. (213 aa)
SUS6Sucrose synthase 6; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (942 aa)
F6I1.3Ubiquitin domain-containing protein. (114 aa)
HSP70-4Heat shock 70 kDa protein 4; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). ATP-dependent molecular chaperone that assists folding of unfolded or misfolded proteins under stress conditions. Mediates plastid precursor degradation to prevent cytosolic precursor accumulation, together with the E3 ubiquitin-protein ligase CHIP. Recognizes specific sequence motifs in tr [...] (650 aa)
CWINV5Beta-fructofuranosidase, insoluble isoenzyme CWINV5. (572 aa)
ACS10Probable aminotransferase ACS10; Probable aminotransferase. Does not have 1-aminocyclopropane- 1-carboxylate synthase (ACS) activity, suggesting that it is not involved in ethylene biosynthesis. (557 aa)
SUS4Sucrose synthase 4; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
SUS3Sucrose synthase 3; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. (809 aa)
F12M16.29Ubiquitin domain-containing protein. (114 aa)
PGD16-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
PATBifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase; Prokaryotic-type aspartate aminotransferase. Has also a prenate transaminase activity. Involved in the aromatic amino acids biosynthesis pathway via the arogenate route. Required for the transamination of prephenate into arogenate. Required for early development of the embryo. (475 aa)
PFP-ALPHA1Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1; Regulatory subunit of pyrophosphate--fructose 6-phosphate 1- phosphotransferase; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily. (614 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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