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GLN2 GLN2 LACS2 LACS2 LACS4 LACS4 HKL3 HKL3 LACS5 LACS5 LACS8 LACS8 APL4 APL4 T28P16.12 T28P16.12 GBSS1 GBSS1 LBD41 LBD41 T16L24.30 T16L24.30 SUS3 SUS3 SUS4 SUS4 GLN1-3 GLN1-3 HKL1 HKL1 T21E18.7 T21E18.7 T21E18.8 T21E18.8 AAE16 AAE16 HXK3 HXK3 SUS6 SUS6 GLN1-4 GLN1-4 MIO24.3 MIO24.3 AACT1 AACT1 LACS9 LACS9 BZIP8 BZIP8 LACS3 LACS3 F28G11.11 F28G11.11 AAE15 AAE15 F13O11.3 F13O11.3 AAT1 AAT1 LACS6 LACS6 LACS7 LACS7 T4C12_30 T4C12_30 GLN1-2 GLN1-2 PGI1 PGI1 GLN1-5 GLN1-5 ATHXK4 ATHXK4 A0A1P8ARU2 A0A1P8ARU2 A0A1P8B2A8 A0A1P8B2A8 F6N18.16 F6N18.16 SUS5 SUS5 LACS1 LACS1 F24G24.60 F24G24.60 ADH1 ADH1 PGIC PGIC LOX2 LOX2 AP2 AP2 SUS1 SUS1 APS1 APS1 ADG2 ADG2 APL2 APL2 APL3 APL3 HXK2 HXK2 SUS2 SUS2 HXK1 HXK1 GLN1-1 GLN1-1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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GLN2Glutamine synthetase, chloroplastic/mitochondrial; The light-modulated chloroplast/mitochondrial enzyme, encoded by a nuclear gene and expressed primarily in leaves, is responsible for the reassimilation of the ammonia generated by photorespiration. Belongs to the glutamine synthetase family. (430 aa)
LACS2Long chain acyl-CoA synthetase 2; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Acts in the cutin pathway. Preferentially uses palmitate, palmitoleate, oleate and linoleate. Required for repression of lateral root formation through its role in cutin biosynthesis and subsequent aerial tissues permeability. Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
LACS4Long chain acyl-CoA synthetase 4; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (666 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
LACS5Long chain acyl-CoA synthetase 5; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (666 aa)
LACS8Long chain acyl-CoA synthetase 8; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (720 aa)
APL4Probable glucose-1-phosphate adenylyltransferase large subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP (By similarity); Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (523 aa)
T28P16.12Probable fructokinase-1; May play an important role in maintaining the flux of carbon towards starch formation. (325 aa)
GBSS1Granule-bound starch synthase 1, chloroplastic/amyloplastic; Required for the synthesis of amylose. Destroyed as it is released from the starch granules during the night. The circadian expression is controlled by CCA1 and LHY transcription factors. (610 aa)
LBD41LOB domain-containing protein 41. (263 aa)
T16L24.30Probable fructokinase-4; May play an important role in maintaining the flux of carbon towards starch formation. (326 aa)
SUS3Sucrose synthase 3; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. (809 aa)
SUS4Sucrose synthase 4; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
GLN1-3Glutamine synthetase cytosolic isozyme 1-3; Low-affinity glutamine synthetase. May contribute to the homeostatic control of glutamine synthesis in roots. (354 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
T21E18.7Probable fructokinase-3; May play an important role in maintaining the flux of carbon towards starch formation. (345 aa)
T21E18.8Probable fructokinase-2; May play an important role in maintaining the flux of carbon towards starch formation. (329 aa)
AAE16Probable acyl-activating enzyme 16, chloroplastic; May be involved in the activation of fatty acids to acyl- carrier-protein; Belongs to the ATP-dependent AMP-binding enzyme family. (722 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
SUS6Sucrose synthase 6; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (942 aa)
GLN1-4Glutamine synthetase cytosolic isozyme 1-4; High-affinity glutamine synthetase. May contribute to the homeostatic control of glutamine synthesis in roots. (356 aa)
MIO24.3Probable fructokinase-7; May play an important role in maintaining the flux of carbon towards starch formation. (343 aa)
AACT1Probable acetyl-CoA acetyltransferase, cytosolic 2; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
LACS9Long chain acyl-CoA synthetase 9, chloroplastic; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate. (691 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
LACS3Long chain acyl-CoA synthetase 3; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
F28G11.11Probable fructokinase-6, chloroplastic; May play an important role in maintaining the flux of carbon towards starch formation; Belongs to the carbohydrate kinase PfkB family. (384 aa)
AAE15Long-chain-fatty-acid--[acyl-carrier-protein] ligase AEE15, chloroplastic; Probably involved in the activation of fatty acids to acyl- carrier-protein prior to fatty acid elongation in plastids. Acts on medium- to long-chain fatty acids. (727 aa)
F13O11.3Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
AAT1Acetyl-CoA acetyltransferase, cytosolic 1. (403 aa)
LACS6Long chain acyl-CoA synthetase 6, peroxisomal; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate. Might play a regulatory role both in fatty acid import into glyoxysomes and in fatty acid beta-oxidation. Displays redundant function with LACS7 into the seed development process. (701 aa)
LACS7Long chain acyl-CoA synthetase 7, peroxisomal; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate. Displays redundant function with LACS7 into the seed development process (By similarity). (700 aa)
T4C12_30Alcohol dehydrogenase-like 6. (381 aa)
GLN1-2Glutamine synthetase cytosolic isozyme 1-2; Low-affinity glutamine synthetase. May contribute to the homeostatic control of glutamine synthesis in roots. (356 aa)
PGI1Glucose-6-phosphate isomerase 1, chloroplastic; Promotes the synthesis of starch in leaves. (613 aa)
GLN1-5Glutamine synthetase cytosolic isozyme 1-5; Belongs to the glutamine synthetase family. (353 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
A0A1P8B2A8Long chain acyl-CoA synthetase. (130 aa)
F6N18.16Alcohol dehydrogenase-like 3. (394 aa)
SUS5Sucrose synthase 5; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (836 aa)
LACS1Long chain acyl-CoA synthetase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Acts in both the wax and cutin pathways. Preferentially uses palmitate, palmitoleate, linoleate and eicosenoate. Seems to have a specific activity against very long-chain fatty acid (VLCFA) class with acids longer than 24 carbons (C(24)). (660 aa)
F24G24.60Probable fructokinase-5; May play an important role in maintaining the flux of carbon towards starch formation. (324 aa)
ADH1Alcohol dehydrogenase class-P; Alcohol dehydrogenase mostly active on ethanol (EtOH), but exhibits broad substrates selectivity for primary and secondary alcohols (e.g. butanol, propyl alcohol, pentanol, isopentanol, ethylene glycol, isopropanol, methanol and tertiary butyl alcohol). Converts allyl alcohol to highly toxic acryl- aldehyde. Required for survival and acclimation in hypoxic conditions, especially in roots. (379 aa)
PGICGlucose-6-phosphate isomerase, cytosolic; Belongs to the GPI family. (560 aa)
LOX2Lipoxygenase 2, chloroplastic; 13S-lipoxygenase that can use linolenic acid as substrates. Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure. Required for the wound-induced synthesis of jasmonic acid (JA) in leaves. (896 aa)
AP2Floral homeotic protein APETALA 2; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and [...] (432 aa)
SUS1Sucrose synthase 1; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
APS1Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (520 aa)
ADG2Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (522 aa)
APL2Glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (518 aa)
APL3Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic; This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP. (521 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
SUS2Sucrose synthase 2; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and directs carbon towards starch synthesis in developing seeds. (807 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
GLN1-1Glutamine synthetase cytosolic isozyme 1-1; High-affinity glutamine synthetase. May contribute to the homeostatic control of glutamine synthesis in roots. (356 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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