STRINGSTRING
DCL DCL BIK1 BIK1 RLP23 RLP23 LYK4 LYK4 ZIP1 ZIP1 TUFA TUFA RLK5 RLK5 P5CSA P5CSA P5CSB P5CSB SBT6.1 SBT6.1 PIP1 PIP1 WAK1 WAK1 RGF1 RGF1 RGF7 RGF7 LYM3 LYM3 GLR3.6 GLR3.6 MIK2 MIK2 RGF6 RGF6 LYM1 LYM1 SERK1 SERK1 BAK1 BAK1 LECRK55 LECRK55 BIR1 BIR1 GLR3.3 GLR3.3 RLK RLK AMC3 AMC3 AMC9 AMC9 PEPR2 PEPR2 NIK1 NIK1 GRI GRI RKL1 RKL1 PRK5 PRK5 LECRK19 LECRK19 LECRK18 LECRK18 RALF23 RALF23 PEP1 PEP1 LECRK62 LECRK62 WAKL17 WAKL17 LECRK15 LECRK15 LECRK11 LECRK11 BGAL1 BGAL1 SOBIR1 SOBIR1 SERK4 SERK4 PEPR1 PEPR1 SBT3.8 SBT3.8 SYP121 SYP121 TUFA-2 TUFA-2 CERK1 CERK1 RGI3 RGI3 RLK7 RLK7 LYK5 LYK5 LYM2 LYM2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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DCLProtein DCL homolog, chloroplastic; Required for normal plastid function and plant development. Required for correct plastid ribosome assembly. Required for processing and maturation of 4.5S rRNA. (219 aa)
BIK1Serine/threonine-protein kinase BIK1; Plays a central role in immune responses. Required to activate the resistance responses to necrotrophic pathogens. Phosphorylates FLS2 and BAK1. Involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling and defense responses downstream of FLS2. Acts additively with PBL1 in PTI defenses. Acts as positive regulator of the PAMP flg22-induced increase of cytosolic calcium. Binds directly and phosphorylates the NADPH oxidase RBOHD at specific sites in a calcium-independent manner to enhance reactive oxygen species (ROS) [...] (395 aa)
RLP23Receptor like protein 23; Involved in the perception of necrosis and ethylene-inducing peptide 1-like proteins (NLPs), that act as extracellular signals mediating immune activation. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. (890 aa)
LYK4LysM domain receptor-like kinase 4; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity. Recognizes microbe-derived N- acetylglucosamine (NAG)-containing ligands. Involved in the resistance to the pathogenic fungus Alternaria brassicicola and to the bacterial pathogen the bacterial pathogen Pseudomonas syringae pv tomato DC3000, probably by sensing microbe-associated molecular pattern (MAMP) and pathogen-associated molecular patterns (PAMP). May play a role in detecting peptidoglyca [...] (612 aa)
ZIP1Zinc transporter 1; Mediates zinc uptake from the rhizosphere. May also transport copper and cadmium ions. (355 aa)
TUFAElongation factor Tu, chloroplastic; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (476 aa)
RLK5Receptor-like protein kinase 5; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates that controls floral organ abscission. May interact with the 'INFLORESCENCE DEFICIENT IN ABSCISSION' (IDA) ligands family. (999 aa)
P5CSADelta-1-pyrroline-5-carboxylate synthase A; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family. (717 aa)
P5CSBDelta-1-pyrroline-5-carboxylate synthase B; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family. (726 aa)
SBT6.1Subtilisin-like protease SBT6.1; Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane- associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N- [...] (1038 aa)
PIP1PAMP-induced secreted peptide 1; Endogenous secreted peptide that acts as elicitor of immune response and positive regulator of defense response. Amplifies the immune response triggered by flg22, the active epitope of bacterial flagellin. Acts as negative regulator of root growth. (72 aa)
WAK1Wall-associated receptor kinase 1; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. Required during plant's response to pathogen infection and in plant defense against heavy metal toxicity. Phosphorylates the oxygen-evolving enhancer protein 2 (OEE2) in an GRP-3-dependent manner. (735 aa)
RGF1Root meristem growth factor 1; Maintains the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT), mainly at the post-transcriptional level. Belongs to the RGF family. (116 aa)
RGF7Root meristem growth factor 7; Maintains the postembryonic root stem cell niche. Belongs to the RGF family. (102 aa)
LYM3LysM domain-containing GPI-anchored protein 3; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (423 aa)
GLR3.6Glutamate receptor 3.6; Glutamate-gated receptor that probably acts as non-selective cation channel. Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. (903 aa)
MIK2MDIS1-interacting receptor like kinase 2; Involved in the pollen tube perception of the female signal. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1045 aa)
RGF6Root meristem growth factor 6; Maintains the postembryonic root stem cell niche. Belongs to the RGF family. (86 aa)
LYM1LysM domain-containing GPI-anchored protein 1; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (416 aa)
SERK1Somatic embryogenesis receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. (625 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
LECRK55L-type lectin-domain containing receptor kinase V.5; Confers resistance to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici, but confers susceptibility to the pathogenic bacteria Pseudomonas syringae. In the N-terminal section; belongs to the leguminous lectin family. (661 aa)
BIR1Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380. (620 aa)
GLR3.3Glutamate receptor 3.3; Glutamate-gated receptor that probably acts as non-selective cation channel, at least in roots and hypocotyls. Can be triggered by Ala, Asn, Cys, Glu, Gly, Ser and glutathione (a tripeptide consisting of Glu-Gly-Cys). Mediates leaf-to-leaf wound signaling. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. (933 aa)
RLKLeucine-rich repeat receptor-like protein kinase. (751 aa)
AMC3Metacaspase-3. (362 aa)
AMC9Metacaspase-9 subunit p10; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Required for proteolytic processing of GRI. Belongs to the peptidase C14B family. (325 aa)
PEPR2Leucine-rich repeat receptor-like protein kinase PEPR2; Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP- inducible plant responses (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1088 aa)
NIK1Protein NSP-INTERACTING KINASE 1; Involved in defense response to geminivirus and begomovirus infection via regulation of the nuclear trafficking of RPL10A. Phosphorylates RPL10A in vitro. Activation of NIK1 downregulates cytosolic translation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (638 aa)
GRIProtein GRIM REAPER; Involved in the regulation of cell death induced by extracellular reactive oxygen species. Only the processed peptide, and not the full length GRI can bind in vivo to the extracellular domain of the receptor PRK5. The GRIp-induced cell death is superoxide and salicylic acid dependent. Belongs to the STIG1 family. (168 aa)
RKL1Probable inactive receptor kinase At1g48480; Belongs to the protein kinase superfamily. (655 aa)
PRK5Pollen receptor-like kinase 5; Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth. The extracellular domain serves as a sensor for peptides derived from GRI. May act as a downstream element for ROS-dependent cell death induced by GRI. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (686 aa)
LECRK19L-type lectin-domain containing receptor kinase I.9; Essential receptor for extracellular ATP. Binds ATP with high affinity through its extracellular legume-lectin like region. Is required for ATP-induced intracellular calcium response, mitogen-activated protein kinase 3 (MPK3) and MPK6 activation and ATP-induced gene expression. May play a variety of roles in stress resistance. May be involved in protein-protein interactions with RGD motif-containing proteins as potential ligands. Plays probably a structural and signaling role at the plant cell surfaces. (766 aa)
LECRK18L-type lectin-domain containing receptor kinase I.8; Involved in resistance response to the pathogenic fungus Alternaria brassicicola; In the N-terminal section; belongs to the leguminous lectin family. (657 aa)
RALF23Rapid alkalinization factor 23; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity). Regulates negatively brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation). (138 aa)
PEP1Elicitor peptide 1; Elicitor of plant defense. Induces the production of plant defensin (PDF1.2) and of H(2)O(2). Promotes resistance to the root fungal pathogen P.irregulare. (92 aa)
LECRK62L-type lectin-domain containing receptor kinase VI.2; Involved in negative regulation of abscisic acid response in seed germination; In the N-terminal section; belongs to the leguminous lectin family. (682 aa)
WAKL17Wall-associated receptor kinase-like 17; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (786 aa)
LECRK15Probable L-type lectin-domain containing receptor kinase I.5; In the N-terminal section; belongs to the leguminous lectin family. (674 aa)
LECRK11Putative L-type lectin-domain containing receptor kinase I.1; Involved in resistance response to the pathogenic fungus Alternaria brassicicola; In the N-terminal section; belongs to the leguminous lectin family. (682 aa)
BGAL1Beta-galactosidase 1. (847 aa)
SOBIR1Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission. (641 aa)
SERK4Somatic embryogenesis receptor kinase 4; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Positively regulates the BR-dependent plant growth pathway and negatively regulates the BR-independent cell- death pathway. (620 aa)
PEPR1Leucine-rich repeat receptor-like protein kinase PEPR1; Acts as a receptor for PEP defense peptides. Unlike typical immune receptors, senses an endogenous elicitor that potentiates pathogen-associated molecular pattern (PAMP)-inducible plant responses. Involved in PAMP-triggered immunity (PTI) signaling. Interacts with and phosphorylates the kinase BIK1, a central rate-limiting kinase in PTI signaling. (1123 aa)
SBT3.8Subtilisin-like protease SBT3.8. (775 aa)
SYP121Syntaxin-121; Vesicle trafficking protein that functions in the secretory pathway; Belongs to the syntaxin family. (346 aa)
TUFA-2Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (454 aa)
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
RGI3LRR receptor-like serine/threonine-protein kinase; Acts as receptor of RGF1, a peptide hormone that maintains the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT). Links RGF1 signal with its downstream components. (1091 aa)
RLK7Receptor-like protein kinase 7; Plays a role in pattern-triggered immunity (PTI) signaling induced by pathogen-associated molecular patterns (PAMPs). Acts as a receptor for PIP1 defense peptide. PIP1 is an endogenous secreted peptide that acts as elicitor of immune response and positive regulator of defense response. Involved in the control of seed germination speed, in tolerance to oxidative stress and in maintaining seed longevity. (977 aa)
LYK5Protein LYK5; May recognize microbe-derived N-acetylglucosamine (NAG)- containing ligands; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (664 aa)
LYM2LysM domain-containing GPI-anchored protein 2; Chitin elicitor-binding protein involved in the perception of chitin oligosaccharide elicitor. (350 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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