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PGM3 PGM3 TUBB1 TUBB1 GAPC1 GAPC1 PGIC PGIC MDH1 MDH1 HXK2 HXK2 HKL3 HKL3 VDAC1 VDAC1 PGM2 PGM2 PGMP PGMP PGK3 PGK3 HKL1 HKL1 HXK3 HXK3 GAPC2 GAPC2 T25N20.10 T25N20.10 PSAT1 PSAT1 PGI1 PGI1 ATHXK4 ATHXK4 HXK1 HXK1 SKP1A SKP1A A0A1P8ARU2 A0A1P8ARU2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGM3Probable phosphoglucomutase, cytoplasmic 1; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. (583 aa)
TUBB1Tubulin beta-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
GAPC1Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Required for full fertility. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Associates with FBA6 to [...] (338 aa)
PGICGlucose-6-phosphate isomerase, cytosolic; Belongs to the GPI family. (560 aa)
MDH1Malate dehydrogenase 1, cytoplasmic; Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments. (332 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
VDAC1Mitochondrial outer membrane protein porin 1; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance. (276 aa)
PGM2Probable phosphoglucomutase, cytoplasmic 2; This enzyme participates in both the breakdown and synthesis of glucose. (585 aa)
PGMPPhosphoglucomutase, chloroplastic; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. (623 aa)
PGK3Phosphoglycerate kinase 3, cytosolic; Belongs to the phosphoglycerate kinase family. (401 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
GAPC2Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity). Binds DNA in vitro. (338 aa)
T25N20.10Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein. (205 aa)
PSAT1Phosphoserine aminotransferase 1, chloroplastic; Involved in the plastidial phosphorylated pathway of serine biosynthesis (PPSB). Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (430 aa)
PGI1Glucose-6-phosphate isomerase 1, chloroplastic; Promotes the synthesis of starch in leaves. (613 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
SKP1ASKP1-like protein 1A; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicate [...] (160 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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