STRINGSTRING
rbcL rbcL BRI1 BRI1 PSBY PSBY CYP90B1 CYP90B1 PCR3 PCR3 PETE PETE FD2 FD2 PSBO1 PSBO1 GAPA1 GAPA1 PSBR PSBR SBPASE SBPASE PSAN PSAN psaA psaA psaB psaB LHCA1 LHCA1 XTH22 XTH22 DET2 DET2 Lhb1B1 Lhb1B1 PSBW PSBW PSBP1 PSBP1 BZR1 BZR1 CYP85A2 CYP85A2 BAK1 BAK1 CYP90D1 CYP90D1 LHCA5 LHCA5 LHCB7 LHCB7 GLK2 GLK2 CYP85A1 CYP85A1 BZR2 BZR2 PSB27-1 PSB27-1 BSU1 BSU1 CYP90C1 CYP90C1 LHCB2.2 LHCB2.2 PSAG PSAG PSAF PSAF GLK1 GLK1 PSAL PSAL PSAK PSAK LHCA2 LHCA2 LHCB5 LHCB5 PSBS PSBS PSBQ1 PSBQ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rbcLRibulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (479 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
PSBYPhotosystem II core complex proteins psbY, chloroplastic; PSBY-1 and -2 are manganese-binding polypeptides with L- arginine metabolizing enzyme activity. They are a component of the core of photosystem II. (189 aa)
CYP90B1Cytochrome P450 90B1; Catalyzes the C22-alpha-hydroxylation step in brassinosteroids biosynthesis. Converts campestanol to 6- deoxocathasterone and 6-oxocampestanol to cathasterone. (513 aa)
PCR3Protein PLANT CADMIUM RESISTANCE 3; May be involved in heavy metals transport; Belongs to the cornifelin family. (152 aa)
PETEPlastocyanin minor isoform, chloroplastic; Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. Seems to be a minor plastocyanin in Arabidopsis. (171 aa)
FD2Ferredoxin-2, chloroplastic; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the 2Fe2S plant-type ferredoxin family. (148 aa)
PSBO1Oxygen-evolving enhancer protein 1-1, chloroplastic; Stabilizes the manganese cluster which is the primary site of water splitting. (332 aa)
GAPA1Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic; Involved in the photosynthetic reductive pentose phosphate pathway (Calvin-Benson cycle). Catalyzes the reduction of 1,3- diphosphoglycerate by NADPH (By similarity). (396 aa)
PSBRPhotosystem II 10 kDa polypeptide, chloroplastic; Associated with the oxygen-evolving complex of photosystem II. (140 aa)
SBPASESedoheptulose-1,7-bisphosphatase, chloroplastic; Belongs to the FBPase class 1 family. (393 aa)
PSANPhotosystem I reaction center subunit N, chloroplastic; May function in mediating the binding of the antenna complexes to the PSI reaction center and core antenna. Plays an important role in docking plastocyanin to the PSI complex. Does not bind pigments. (171 aa)
psaAPhotosystem I P700 chlorophyll a apoprotein A1; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (750 aa)
psaBPhotosystem I P700 chlorophyll a apoprotein A2; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (734 aa)
LHCA1Chlorophyll a-b binding protein 6, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. (241 aa)
XTH22Xyloglucan endotransglucosylase/hydrolase protein 22; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Its induction in case of mechanical stress, suggests that it may contribute in the adaptive changes in morphogenesis by being recruited to alter tissues tensil strength, or flexibility, enabling adaptation to mechanically stressful environments; Belongs to the glycosyl hydrolase 16 family. XTH [...] (284 aa)
DET2Steroid 5-alpha-reductase DET2; Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide; acts at the second step in brassinolide biosynthesis in the 5alpha-reduction of (24R)- 24-methylcholest-4-en-3- one, which is further modified to form campestanol. Can use progesterone, testosterone, androstenedione and campestenone as substrate. (262 aa)
Lhb1B1Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (266 aa)
PSBWPhotosystem II reaction center W protein, chloroplastic; Stabilizes dimeric photosystem II (PSII). In its absence no dimeric PSII accumulates and there is a reduction of monomeric PSII. Belongs to the psbW family. (133 aa)
PSBP1Oxygen-evolving enhancer protein 2-1, chloroplastic; May be involved in the regulation of photosystem II; Belongs to the psbP family. (263 aa)
BZR1Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). (336 aa)
CYP85A2Cytochrome P450 85A2; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone, and castasterone to brassinolide. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6- deoxotyphasterol to typhasterol; Belongs to the cytochrome P450 family. (465 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
CYP90D13-epi-6-deoxocathasterone 23-monooxygenase CYP90D1; Involved in brassinosteroid (BR) biosynthesis. May convert teasterone to 3- dehydroteasterone, or 6-deoxoteasterone to 3-dehydro-6-deoxoteasterone. C-23 hydroxylase that converts directly (22S,24R)- 22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3- dehydro-6-deoxoteasterone and 6-deoxotyphasterol, respectively. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6-deoxoteasterone. (491 aa)
LHCA5Photosystem I chlorophyll a/b-binding protein 5, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Seems involved in the function of the photosystem I in low light conditions, when other LHCA proteins are less abundant. Required, together with LHCA6, for the formation of a full-size NAD(P)H dehydrogenase-photosystem I supercomplex (NDH-PSI) that triggers cyclic and chlororespiratory electron transport in chloroplast thylakoids, especially under stress condition [...] (256 aa)
LHCB7Chlorophyll a-b binding protein 7, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (Probable). Probably functions in non-photochemical quenching (NPQ) to dissipate energy under conditions where the absorbed light exceeds the electron transfer capacities of the thylakoid complexes contributing to primary photochemistry ; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (327 aa)
GLK2Transcription activator GLK2; Transcriptional activator that functions with GLK1 to promote chloroplast development. Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport. Acts in a cell-autonomous manner to coordinate and maintain the photosynthetic apparatus within individual cells. May function in photosynthetic capacity optimization by integrating responses to variable environmental and endogenous cues. Prevents premature senescence. (386 aa)
CYP85A1Cytochrome P450 85A1; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6-deoxotyphasterol to typhasterol. (465 aa)
BZR2Protein BRASSINAZOLE-RESISTANT 2; Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N- terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C- terminal domain is probably involved in transcriptional activation. Recruits the transcription elongation factor IWS1 to control BR- regulated gene expression. Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-reg [...] (335 aa)
PSB27-1Photosystem II repair protein PSB27-H1, chloroplastic; Probably involved in repair of photodamaged photosystem II (PSII). (174 aa)
BSU1Serine/threonine-protein phosphatase BSU1; Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling. Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs. Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200'. (793 aa)
CYP90C13-epi-6-deoxocathasterone 23-monooxygenase CYP90C1; Involved in brassinosteroid (BR) biosynthesis. Converts typhasterol to castasterone and 6-deoxotyphasterol to 6-deoxocastasterone. C-23 hydroxylase that converts directly (22S,24R)- 22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3- dehydro-6-deoxoteasterone and 6-deoxotyphasterol, respectively. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6-deoxoteasterone. Required for the regulation of polar elongation of leaf cells. Required for the longitudinal elongation of floral organs. (524 aa)
LHCB2.2Chlorophyll a-b binding protein 2.2, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity). Mediates rapid phosphorylation and migration of LHCII-PSII to photosystem I (PSI) after transition to state 2 (red) light conditions, thus leading to the formation of PSI-PSII-LHCII and PSI-LHCII supercomplex to balance the relative excitation of PSI and PSII. Involved in the production of reactive oxygen species (ROS) and stomatal closure upon abscisic acid ( [...] (265 aa)
PSAGPhotosystem I reaction center subunit V, chloroplastic; Not yet known; Belongs to the PsaG/PsaK family. (160 aa)
PSAFPhotosystem I reaction center subunit III, chloroplastic; Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI. (221 aa)
GLK1Transcription activator GLK1; Transcriptional activator that functions with GLK2 to promote chloroplast development. Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport. Acts in a cell-autonomous manner to coordinate and maintain the photosynthetic apparatus within individual cells. May function in photosynthetic capacity optimization by integrating responses to variable environmental and endogenous cues. Prevents premature senescence. (420 aa)
PSALPhotosystem I reaction center subunit XI, chloroplastic; Belongs to the PsaL family. (219 aa)
PSAKPhotosystem I reaction center subunit psaK, chloroplastic. (130 aa)
LHCA2Photosystem I chlorophyll a/b-binding protein 2, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated, here photosystem I. (257 aa)
LHCB5Chlorophyll a-b binding protein CP26, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (280 aa)
PSBSPhotosystem II 22 kDa protein, chloroplastic; Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. Is not necessary for efficient light harvesting and photosynthesis. Belongs to the ELIP/psbS family. (265 aa)
PSBQ1Oxygen-evolving enhancer protein 3-1, chloroplastic; Required for photosystem II assembly/stability and photoautotrophic growth under low light conditions. (224 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.