STRINGSTRING
NAC013 NAC013 NAC098 NAC098 AT2G41640 AT2G41640 NAC029 NAC029 HSFA2 HSFA2 DREB2A DREB2A HSP17.4A HSP17.4A HSP18.1 HSP18.1 HSP21 HSP21 XTH31 XTH31 NAC002 NAC002 MAF5 MAF5 Q6NKN2_ARATH Q6NKN2_ARATH NAC047 NAC047 HSA32 HSA32 ATG9 ATG9 NAC053 NAC053 ACT2 ACT2 T29A15.210 T29A15.210 NAC019 NAC019 NAC92 NAC92 NAC055 NAC055 NCED3 NCED3 MBF1C MBF1C GLK1 GLK1 WRKY17 WRKY17 JUB1 JUB1 HSFA7A HSFA7A WRKY11 WRKY11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAC013NAC domain-containing protein 13; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'- CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance. (528 aa)
NAC098Protein CUP-SHAPED COTYLEDON 2; Transcription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of [...] (375 aa)
AT2G41640Glycosyltransferase family 61 protein. (500 aa)
NAC029NAC transcription factor 29; Transcription activator that binds to, and transactivates the promoter of the abscisic aldehyde oxidase AAO3. Promotes chlorophyll degradation in leaves by enhancing transcription of AAO3, which leads to increased levels of the senescence-inducing hormone abscisic acid (ABA). Involved in the control of dehydration in senescing leaves. Binds to the DNA sequence 5'-CACGTAAGT-3' of SAG113 promoter. SAG113 acts as negative regulator of ABA signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Transcription factor of the NAC f [...] (268 aa)
HSFA2Heat stress transcription factor A-2; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). Belongs to the HSF family. Class A subfamily. (345 aa)
DREB2ADehydration-responsive element-binding protein 2A; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Belongs to the AP2/ERF transcription factor family. ERF subfamily. (335 aa)
HSP17.4A17.4 kDa class I heat shock protein. (156 aa)
HSP18.118.1 kDa class I heat shock protein. (161 aa)
HSP21Heat shock protein 21, chloroplastic; Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. Belongs to the small heat shock protein (HSP20) family. (227 aa)
XTH31Xyloglucan endotransglucosylase/hydrolase protein 31; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Involved in the accumulation of hemicelluloses. Has a high XEH activity and only a slight XET activity in vitro, but the main in planta activity seems to be XET, thus controlling aluminum sensitivity. Acceptor preferences are XXXGol = XXFGol > XXLGol > XLLGol = XLFGol ; Belongs to the glycosyl [...] (293 aa)
NAC002NAC domain-containing protein 2. (289 aa)
MAF5Protein MADS AFFECTING FLOWERING 5; Transcription factor involved in the negative regulation of flowering time in short days, probably through the photoperiodic and vernalization pathways. Prevents premature flowering, particularly in the cv. Landsberg erecta background. In non-inductive photoperiods (e.g. short days), required for flowering through VIL2-mediated maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)- dependent H3K27me3. (198 aa)
Q6NKN2_ARATHAlpha/beta-Hydrolases superfamily protein. (566 aa)
NAC047NAC transcription factor 47; Transcription factor that binds to the promoter of ACO5, an ACC oxidase involved in ethylene biosynthesis. Mediates waterlogging- induced hyponastic leaf movement, and cell expansion in abaxial cells of the basal petiole region, by directly regulating the expression of ACO5. Required for normal seed development and morphology. (359 aa)
HSA32Protein HEAT-STRESS-ASSOCIATED 32; Transactivator required, together with HSP101, for long-term acquired thermotolerance (LAT) maintenance, probably by regulating heat-inducible genes expression, thus being a cellular component of thermomemory. (286 aa)
ATG9Autophagy-related protein 9; Required for autophagy that plays an essential role in plant nutrient recycling. Contributes to efficient autophagic flux, especially in early autophagic process prior to the fusion of the autophagosome with the vacuole. Belongs to the ATG9 family. (866 aa)
NAC053NAC domain-containing protein 53; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (Ref.6,. Promotes reactive oxygen species (ROS) production during drought-induced leaf senescence. In response to abscisic acid (ABA)-mediated drought stress signals, binds directly to the promoters of RBOHC and RBOHE genes, encoding ROS biosynthetic enzymes, resulting in ROS accumulation and triggering leaf senescence via programmed cell death (PCD). ROS-induced leaf senescence sustains plant survival under drought conditions. Involved in heat [...] (549 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
T29A15.210Major facilitator superfamily protein. (460 aa)
NAC019NAC domain-containing protein 19; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
NAC92NAC domain-containing protein 92; Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[ACG][CA]GT[AG](5- 6n)[CT]AC[AG]-3'. Promotes lateral root development. Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)- dependent signaling pathways. Regulates also genes during seed germination. Regulates positively aging-induced cell death. Involved in age-related resistance (ARR) against Pseudomonas syringae pv. t [...] (285 aa)
NAC055NAC domain-containing protein 55; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
NCED39-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids, in response to water stress. (599 aa)
MBF1CMultiprotein-bridging factor 1c; Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators. Involved in the tolerance to heat and osmotic stress by partially activating the ethylene-response signal transduction pathway. Belongs to the MBF1 family. (148 aa)
GLK1Transcription activator GLK1; Transcriptional activator that functions with GLK2 to promote chloroplast development. Acts as an activator of nuclear photosynthetic genes involved in chlorophyll biosynthesis, light harvesting, and electron transport. Acts in a cell-autonomous manner to coordinate and maintain the photosynthetic apparatus within individual cells. May function in photosynthetic capacity optimization by integrating responses to variable environmental and endogenous cues. Prevents premature senescence. (420 aa)
WRKY17Probable WRKY transcription factor 17; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). (321 aa)
JUB1Transcription factor JUNGBRUNNEN 1; Transcription factor that binds to the 5'- RRYGCCGT-3' consensus core sequence. Central longevity regulator. Negative regulator of leaf senescence. Modulates cellular H(2)O(2) levels and enhances tolerance to various abiotic stresses through the regulation of DREB2A. (275 aa)
HSFA7AHeat stress transcription factor A-7a; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). (272 aa)
WRKY11Probable WRKY transcription factor 11; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000, probably by activating the jasmonic acid (JA)- signaling pathway ; Belongs to the WRKY group II-d family. (325 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (36%) [HD]