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CERK1 CERK1 AHA2 AHA2 AHA1 AHA1 TMK1 TMK1 IAA17 IAA17 RLK1 RLK1 TIR1 TIR1 ACS12 ACS12 YUC6 YUC6 TAR2 TAR2 AUX1 AUX1 TAR3 TAR3 SAUR19 SAUR19 THE1 THE1 TMK4 TMK4 YUC5 YUC5 YUC11 YUC11 ACS10 ACS10 TAR1 TAR1 PIN2 PIN2 HERK1 HERK1 FER4 FER4 TAA1 TAA1 PIN3 PIN3 RALF1 RALF1 TIR TIR YUC2 YUC2 YUC1 YUC1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
AHA2ATPase 2, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Involved in maintaining the membrane potential and delta-pH, together forming the plasma membrane protonmotive force (PMF) required for root and hypocotyl elongation and root tropism. Important for root growth and development during different nitrogen regimes. Forms a functional cation-translocating unit with CNGC17 tha [...] (948 aa)
AHA1ATPase 1, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Forms a functional cation- translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (949 aa)
TMK1Receptor protein kinase TMK1; Transmembrane kinase receptor. Phosphorylates only serine and threonine residues. Involved in auxin signal transduction and cell expansion and proliferation regulation. Forms with ABP1 a cell surface auxin perception complex that activates ROP signaling pathways. Required for auxin promotion of pavement cell interdigitation. Auxin promotes the formation of the ABP1-TMK1 protein complex. (942 aa)
IAA17Auxin-responsive protein IAA17; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (229 aa)
RLK1G-type lectin S-receptor-like serine/threonine-protein kinase RLK1. (832 aa)
TIR1Protein TRANSPORT INHIBITOR RESPONSE 1; Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. The SCF(TIR1) E3 ubiquitin ligase complex is involved in auxin-mediated signaling pathway that regulate root and hypocotyl growth, lateral root formation, cell elongation, and gravitropism. Appears to allow pericycle cells to overcome G2 arrest prior to lateral root development. Plays a role in ethylene signaling in roots. Confers sensitivity to the virulent bacterial pathogen P.syringae. (594 aa)
ACS12Probable aminotransferase ACS12; Probable aminotransferase. Does not have 1-aminocyclopropane- 1-carboxylate synthase (ACS) activity, suggesting that it is not involved in ethylene biosynthesis. (495 aa)
YUC6Indole-3-pyruvate monooxygenase YUCCA6; Involved in auxin biosynthesis via the indole-3-pyruvic acid (IPA) pathway. Also able to convert in vitro phenyl pyruvate (PPA) to phenyl acetic acid (PAA). Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (417 aa)
TAR2Tryptophan aminotransferase-related protein 2; Involved in auxin production. Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are required for proper embryo patterning. Involved in the maintenance of the root stem cell niches. (440 aa)
AUX1Auxin transporter protein 1; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files. Coordinated subcellular localization of AUX1 is regula [...] (485 aa)
TAR3Tryptophan aminotransferase-related protein 3; Probable aminotransferase. (457 aa)
SAUR19Auxin-responsive protein SAUR19; Functions as positive effectors of cell expansion through modulation of auxin transport; Belongs to the ARG7 family. (90 aa)
THE1Receptor-like protein kinase THESEUS 1; Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid-(BR-) independent manner. Mediates the response of growing plant cells to the perturbation of cellulose synthesis and may act as a cell-wall- integrity sensor. Controls ectopic-lignin accumulation in cellulose- deficient mutant backgrounds. (855 aa)
TMK4Receptor-like kinase TMK4; Involved in auxin signal transduction and cell expansion and proliferation regulation. May be involved in brassinosteroid-mediated plant growth and development via auxin regulation. May be involved in microspore and pollen development ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (928 aa)
YUC5Probable indole-3-pyruvate monooxygenase YUCCA5; Involved in auxin biosynthesis. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in roots. (424 aa)
YUC11Probable indole-3-pyruvate monooxygenase YUCCA11; Involved in auxin biosynthesis. Belongs to the FMO family. (391 aa)
ACS10Probable aminotransferase ACS10; Probable aminotransferase. Does not have 1-aminocyclopropane- 1-carboxylate synthase (ACS) activity, suggesting that it is not involved in ethylene biosynthesis. (557 aa)
TAR1Tryptophan aminotransferase-related protein 1; Probably involved in auxin production. TAA1, TAR1 and TAR2 are required for proper embryo patterning. Belongs to the alliinase family. (388 aa)
PIN2Auxin efflux carrier component 2; Acts as a component of the auxin efflux carrier. Seems to be involved in the root-specific auxin transport, and mediates the root gravitropism. Its particular localization suggest a role in the translocation of auxin towards the elongation zone. (647 aa)
HERK1Receptor-like protein kinase HERK 1; Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid-(BR-) independent manner. (830 aa)
FER4Ferritin-4, chloroplastic; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity); Belongs to the ferritin family. (259 aa)
TAA1L-tryptophan--pyruvate aminotransferase 1; L-tryptophan aminotransferase involved in auxin (IAA) biosynthesis. Can convert L-tryptophan and pyruvate to indole-3-pyruvic acid (IPA) and alanine. Catalyzes the first step in IPA branch of the auxin biosynthetic pathway. Required for auxin production to initiate multiple change in growth in response to environmental and developmental cues. It is also active with phenylalanine, tyrosine, leucine, alanine, methionine and glutamine. Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are requ [...] (391 aa)
PIN3Auxin efflux carrier component 3; Acts as a component of the auxin efflux carrier. Seems to be involved in the lateral auxin transport system and mediates tropic growth. Coordinated polar localization of PIN3 is directly regulated by the vesicle trafficking process. (640 aa)
RALF1Protein RALF-like 1; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases. Mostly active in roots. Prevents plant growth (e.g. root and leaf length). Suppresses cell elongation of the primary root by activating the cell surface receptor FER and triggering phosphorylation [...] (120 aa)
TIRToll/interleukin-1 receptor-like protein; Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth (By similarity). (176 aa)
YUC2Indole-3-pyruvate monooxygenase YUCCA2; Involved in auxin biosynthesis. Converts the indole-3-pyruvic acid (IPA) produced by the TAA family to indole-3-acetic acid (IAA). Unable to use tryptamine (TAM) as substrate. Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (415 aa)
YUC1Probable indole-3-pyruvate monooxygenase YUCCA1; Involved in auxin biosynthesis, but not in the tryptamine or the CYP79B2/B3 branches. Catalyzes in vitro the N-oxidation of tryptamine to form N-hydroxyl tryptamine. Involved during embryogenesis and seedling development. Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (414 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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