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PAL4 PAL4 T21H19.40 T21H19.40 HST-2 HST-2 F2P24.13 F2P24.13 T26I12.60 T26I12.60 CCR2-2 CCR2-2 MGN6.20 MGN6.20 F4IZK0_ARATH F4IZK0_ARATH F17A22.2 F17A22.2 CAD5 CAD5 CCOAOMT1 CCOAOMT1 CAD6 CAD6 PAL1 PAL1 PAL2 PAL2 PAL3 PAL3 GA3OX1 GA3OX1 F12L6.8 F12L6.8 CSE CSE DCR DCR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAL4Phenylalanine ammonia-lyase 4; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (707 aa)
T21H19.40Alpha/beta-Hydrolases superfamily protein. (383 aa)
HST-2Shikimate O-hydroxycinnamoyltransferase; Acyltransferase involved in the biosynthesis of lignin. Accepts caffeoyl-CoA and p- coumaroyl-CoA as substrates and transfers the acyl group on both shikimate and quinate acceptors. (433 aa)
F2P24.13Alpha/beta-Hydrolases superfamily protein. (382 aa)
T26I12.60Alpha/beta-Hydrolases superfamily protein. (312 aa)
CCR2-2Cinnamoyl-CoA reductase 2; Cinnamoyl-CoA reductase probably involved in the formation of phenolic compounds associated with the hypersensitive response. Seems not to be involved in lignin biosynthesis. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. (332 aa)
MGN6.20Caffeic acid 3-O-methyltransferase-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (378 aa)
F4IZK0_ARATHAlpha/beta-Hydrolases superfamily protein. (348 aa)
F17A22.2Alpha/beta-Hydrolases superfamily protein. (351 aa)
CAD5Cinnamyl alcohol dehydrogenase 5; Involved in lignin biosynthesis in the floral stem. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5- hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols. (357 aa)
CCOAOMT1Caffeoyl-CoA O-methyltransferase 1; Methylates caffeoyl-CoA to feruloyl-CoA. Has a very low activity with caffeic acid and esculetin. Involved in scopoletin biosynthesis in roots; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily. (259 aa)
CAD6Probable cinnamyl alcohol dehydrogenase 6; Involved in lignin biosynthesis. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH- dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols; Belongs to the zinc-containing alcohol dehydrogenase family. (363 aa)
PAL1Phenylalanine ammonia-lyase 1; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (725 aa)
PAL2Phenylalanine ammonia-lyase 2; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (717 aa)
PAL3Phenylalanine ammonia-lyase 3; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton. (694 aa)
GA3OX1Gibberellin 3-beta-dioxygenase 1; Converts the inactive gibberellin (GA) precursors GA9 and GA20 in the bioactives gibberellins GA4 and GA1. Involved in the production of bioactive GA for vegetative growth and development. Belongs to the iron/ascorbate-dependent oxidoreductase family. GA3OX subfamily. (358 aa)
F12L6.8Alpha/beta-Hydrolases superfamily protein. (317 aa)
CSECaffeoylshikimate esterase; Esterase involved in the biosynthesis of lignin. Hydrolyzes caffeoylshikimate into caffeate and shikimate. Together with 4- coumarate--CoA ligase (4CL), acts on an alternative reaction for the formation of caffeoyl-CoA and bypasses the second reaction of shikimate O-hydroxycinnamoyltransferase (HST). Accepts also 4-coumaroylshikimate as substrate, but with lower activity. According to and posseses monoacylglycerol O-acyltransferase, monoacylglycerol lipase and lysophospholipase activities in vitro. With the association of ACBP2, may promote the degradation o [...] (332 aa)
DCRBAHD acyltransferase DCR; Required for incorporation of 9(10),16-dihydroxy-hexadecanoic acid into cutin. (484 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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