(7 nodes) (2022) Engineering the N-glycosylation pathway of Nicotiana tabacum for molecular pharming using CRISPRCas9. network (Arabidopsis thaliana)

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Your Input:
	FUT11	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans. (501 aa)
	TRPA1	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity). Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production; Belongs to the TrpA family. (275 aa)
	BGLU25	Probable inactive beta-glucosidase 25; Belongs to the glycosyl hydrolase 1 family. (531 aa)
	FUT13	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family. (401 aa)
	MAN7	Mannan endo-1,4-beta-mannosidase 7; Required for both, loosening of the micropylar endosperm, and rupture of the seed coat in germinating seeds. May participate in the hydrolysis of the mannans in the cell wall of germinating seeds. (431 aa)
	FUT12	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase. (513 aa)
	XYLT	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity. (534 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FUT11	FUT12	Q9LJK1	Q9FX97	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	0.907
FUT11	FUT13	Q9LJK1	Q9C8W3	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	0.489
FUT11	XYLT	Q9LJK1	Q9LDH0	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	0.995
FUT12	FUT11	Q9FX97	Q9LJK1	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	0.907
FUT12	FUT13	Q9FX97	Q9C8W3	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	0.497
FUT12	XYLT	Q9FX97	Q9LDH0	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	0.993
FUT13	FUT11	Q9C8W3	Q9LJK1	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	0.489
FUT13	FUT12	Q9C8W3	Q9FX97	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	0.497
FUT13	XYLT	Q9C8W3	Q9LDH0	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	0.928
XYLT	FUT11	Q9LDH0	Q9LJK1	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	Glycoprotein 3-alpha-L-fucosyltransferase A; Involved in cell wall synthesis (Probable). Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the first GlcNAc residue next to the peptide chains in N-glycans.	0.995
XYLT	FUT12	Q9LDH0	Q9FX97	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	Putative fucosyltransferase-like protein; May be involved in cell wall biosynthesis. May act as a fucosyltransferase.	0.993
XYLT	FUT13	Q9LDH0	Q9C8W3	Beta-1,2-xylosyltransferase; Glycosyltransferase involved in the xylosylation of N-glycans. Possesses beta-1,2-xylosyltransferase activity, transferring xylose from UDP-xylose to the core beta-linked mannose of N-glycans. Involved in the biosynthesis of glycoprotein bound N-glycans. Does not require metal ions for its activity.	Alpha-(1,4)-fucosyltransferase; May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes; Belongs to the glycosyltransferase 10 family.	0.928