STRINGSTRING
CLV1 CLV1 RWK1 RWK1 CERK1 CERK1 ERL1 ERL1 LRK10L-2.6 LRK10L-2.6 T25K16.19 T25K16.19 RLP4 RLP4 F4J800_ARATH F4J800_ARATH GDPDL5 GDPDL5 RIC7 RIC7 T19G15.120 T19G15.120 BRI1 BRI1 LYM2 LYM2 dl3070w dl3070w RLP23 RLP23 ACD11 ACD11 ACT3 ACT3 NPR1 NPR1 RKF3 RKF3 SD17 SD17 CRRSP9 CRRSP9 LYM3 LYM3 GDPDL1 GDPDL1 T24G5.130 T24G5.130 Dl4895c Dl4895c EPF2 EPF2 EPF1 EPF1 IRE1B IRE1B MNJ8.18 MNJ8.18 LYM1 LYM1 BAK1 BAK1 BIR1 BIR1 IRE1A IRE1A GDPDL6 GDPDL6 GDPDL4 GDPDL4 ASK4 ASK4 BPA1 BPA1 Q9LIM9_ARATH Q9LIM9_ARATH Q9LIN0_ARATH Q9LIN0_ARATH GDPDL7 GDPDL7 SOBIR1 SOBIR1 CF9 CF9 AGP27 AGP27 GDPDL3 GDPDL3 GH3.2 GH3.2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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CLV1Receptor protein kinase CLAVATA1; Involved in the detection of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3p as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (980 aa)
RWK1Uncharacterized protein At1g24485. (498 aa)
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
ERL1LRR receptor-like serine/threonine-protein kinase ERL1; Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ER and ERL2. Redundantly involved with ER in procambial development regulation. Forms a functional ligand-receptor pair with EPF1 (AC Q8S8I4). Forms a constitutive complex with TMM involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (966 aa)
LRK10L-2.6Glycerophosphodiester phosphodiesterase protein kinase domain-containing GDPDL2; Atypical receptor-like kinase involved in disease resistance. In the N-terminal section; belongs to the glycerophosphoryl diester phosphodiesterase family. (1118 aa)
T25K16.19RNA-binding (RRM/RBD/RNP motifs) family protein. (294 aa)
RLP4Receptor-like protein 4. (626 aa)
F4J800_ARATHER protein carbohydrate-binding protein. (434 aa)
GDPDL5Glycerophosphodiester phosphodiesterase GDPDL5. (729 aa)
RIC7ROP-interactive CRIB motif-containing protein 7. (450 aa)
T19G15.120Transmembrane protein. (305 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
LYM2LysM domain-containing GPI-anchored protein 2; Chitin elicitor-binding protein involved in the perception of chitin oligosaccharide elicitor. (350 aa)
dl3070wPolyketide cyclase/dehydrase and lipid transport superfamily protein. (151 aa)
RLP23Receptor like protein 23; Involved in the perception of necrosis and ethylene-inducing peptide 1-like proteins (NLPs), that act as extracellular signals mediating immune activation. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. (890 aa)
ACD11Accelerated cell death 11; Exhibits selective intermembrane transfer of ceramide-1- phosphate (C1P) and phytoceramide-1-phosphate. Does not transport ceramide (Cer) or GalCer, suggesting a requirement for phosphate in the headgroup for functionality. Transports in vitro sphingosine, but not glycosphigolipids. Has also some in vitro activity with sphingomyelin, a lipid not detected in plant tissues. The transport function may be not directly involved in regulating cell death. Rather, perturbations in the function of ACD11 or related components could be monitored by R-proteins, which the [...] (206 aa)
ACT3Actin-3; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
NPR1Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
RKF3Probable LRR receptor-like serine/threonine-protein kinase RKF3; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (617 aa)
SD17Receptor-like serine/threonine-protein kinase SD1-7; Involved in the regulation of cellular expansion and differentiation. Mediates subcellular relocalization of PUB9 from nucleus to plasma membrane in a protein-phosphorylation-dependent manner. May be involved in the abscisic acid-mediated signaling pathway, at least during germination. (843 aa)
CRRSP9Cysteine-rich repeat secretory protein 9. (324 aa)
LYM3LysM domain-containing GPI-anchored protein 3; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (423 aa)
GDPDL1Glycerophosphodiester phosphodiesterase GDPDL1; Hydrolyzes glycerolphosphoglycerol, glycerophosphocholine and glycerophosphoethanolamine in vitro. (763 aa)
T24G5.130Uncharacterized GPI-anchored protein At5g19230. (189 aa)
Dl4895cRNA-binding (RRM/RBD/RNP motifs) family protein. (313 aa)
EPF2Protein EPIDERMAL PATTERNING FACTOR 2; Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERECTA as major receptor. Inactivated by cleavage by CRSP (AC Q9LNU1). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). (120 aa)
EPF1Protein EPIDERMAL PATTERNING FACTOR 1; Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1). MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERL1 as major receptor. May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily. (104 aa)
IRE1BSerine/threonine-protein kinase/endoribonuclease IRE1b; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses. Required for ER stress- induced autophagy. Belongs to the protein kinase superfamily. [...] (881 aa)
MNJ8.18LOW protein: ammonium transporter 1-like protein. (309 aa)
LYM1LysM domain-containing GPI-anchored protein 1; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (416 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
BIR1Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380. (620 aa)
IRE1ASerine/threonine-protein kinase/endoribonuclease IRE1a; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes. Involved in organ growth regulation. Plays a role in plant immunity and abiotic stress responses. (841 aa)
GDPDL6Glycerophosphodiester phosphodiesterase GDPDL6. (753 aa)
GDPDL4Glycerophosphodiester phosphodiesterase GDPDL4; Involved in primary cell wall organization. Required for the accumulation of crystalline cellulose; Belongs to the glycerophosphoryl diester phosphodiesterase family. (766 aa)
ASK4Shaggy-related protein kinase delta; May mediate extracellular signals to regulate transcription in differentiating cells. (420 aa)
BPA1Binding partner of ACD11 1. (259 aa)
Q9LIM9_ARATHPolyketide cyclase/dehydrase and lipid transport superfamily protein. (152 aa)
Q9LIN0_ARATHPolyketide cyclase/dehydrase and lipid transport superfamily protein. (152 aa)
GDPDL7Glycerophosphodiester phosphodiesterase GDPDL7; Belongs to the glycerophosphoryl diester phosphodiesterase family. (750 aa)
SOBIR1Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission. (641 aa)
CF9Carbohydrate-binding protein. (381 aa)
AGP27Classical arabinogalactan protein 27; Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death. (125 aa)
GDPDL3Glycerophosphodiester phosphodiesterase GDPDL3; Involved in primary cell wall organization. Required for the accumulation of crystalline cellulose. (759 aa)
GH3.2Indole-3-acetic acid-amido synthetase GH3.2; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (549 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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