STRINGSTRING
SWI2 SWI2 LRK10L-1.2 LRK10L-1.2 KAPP KAPP WAK1 WAK1 RLK1 RLK1 T7B11.12 T7B11.12 WAKL22 WAKL22 WAKL9 WAKL9 RLK RLK WAK4 WAK4 WAK5 WAK5 WAK2 WAK2 WAKL13 WAKL13 WAKL11 WAKL11 WAKL16 WAKL16 WAKL17 WAKL17 ABCF4 ABCF4 WAKL8 WAKL8 RLP3 RLP3 CLV1 CLV1 GRP3 GRP3 DDM1 DDM1 A8MQK9_ARATH A8MQK9_ARATH CERK1 CERK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SWI2Switch 2; May be involved in early DNA damage response (By similarity). Probable chromatin remodeling factor. (862 aa)
LRK10L-1.2LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.2; Probable receptor-like serine/threonine-protein kinase involved in abscisic acid (ABA) signaling. Acts as a positive regulator of abiotic stress response. (651 aa)
KAPPProtein phosphatase 2C 70; Dephosphorylates the Ser/Thr receptor-like kinase RLK5. May function as a signaling component in a pathway involving RLK5. Binds and dephosphorylates CLAVATA1 (CLV1). Functions as a negative regulator of the CLV1 signaling in plant development. Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop. Dephosphorylation of SERK1 controls SERK1 internalization. Component of a signaling pathway which mediates adaptation to NaCl stress. Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway. (581 aa)
WAK1Wall-associated receptor kinase 1; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. Required during plant's response to pathogen infection and in plant defense against heavy metal toxicity. Phosphorylates the oxygen-evolving enhancer protein 2 (OEE2) in an GRP-3-dependent manner. (735 aa)
RLK1G-type lectin S-receptor-like serine/threonine-protein kinase RLK1. (832 aa)
T7B11.12Transducin family protein / WD-40 repeat family protein. (1308 aa)
WAKL22Wall-associated receptor kinase-like 22; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Required during plant's response to pathogen infection. (751 aa)
WAKL9Wall-associated receptor kinase-like 9; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (792 aa)
RLKLeucine-rich repeat receptor-like protein kinase. (751 aa)
WAK4Wall-associated receptor kinase 4; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. (738 aa)
WAK5Wall-associated receptor kinase 5; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. (733 aa)
WAK2Wall-associated receptor kinase 2; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. (732 aa)
WAKL13Putative wall-associated receptor kinase-like 13; Putative serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (764 aa)
WAKL11Putative wall-associated receptor kinase-like 11; Putative serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (788 aa)
WAKL16Putative wall-associated receptor kinase-like 16; Putative serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (433 aa)
WAKL17Wall-associated receptor kinase-like 17; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (786 aa)
ABCF4ABC transporter F family member 4; Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily. (723 aa)
WAKL8Wall-associated receptor kinase-like 8; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. (720 aa)
RLP3Receptor-like protein 3; Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance (By similarity). Contributes, with WAKL22/RFO1, to resistance to F.oxysporum (f.) matthioli in cv. Columbia relative to cv. Ty-0 ; Belongs to the RLP family. (756 aa)
CLV1Receptor protein kinase CLAVATA1; Involved in the detection of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3p as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (980 aa)
GRP3Glycine-rich protein 3; Regulates the function of the receptor protein kinase WAK1, and namely the phosphorylation of OEE2. (145 aa)
DDM1ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa)
A8MQK9_ARATHPutative membrane lipoprotein. (93 aa)
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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