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LAC8 LAC8 SWI2 SWI2 SYD SYD CHR10 CHR10 CHR5 CHR5 CHR7 CHR7 CHR4 CHR4 BRI1 BRI1 IRX12 IRX12 AS1 AS1 LAC2 LAC2 TPS8 TPS8 LAC16 LAC16 LAC3 LAC3 BRM BRM LAC10 LAC10 TT10 TT10 CHR11 CHR11 BZR1 BZR1 LAC11 LAC11 BAK1 BAK1 LAC17 LAC17 LAC12 LAC12 LAC14 LAC14 LAC9 LAC9 TPS7 TPS7 LAC1 LAC1 LAC13 LAC13 PKL PKL LAC5 LAC5 LAC7 LAC7 DDM1 DDM1 LAC6 LAC6 CHR8 CHR8 TPS11 TPS11
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LAC8Laccase-8; Lignin degradation and detoxification of lignin-derived products (By similarity). Involved in the flowering time inhibition. (584 aa)
SWI2Switch 2; May be involved in early DNA damage response (By similarity). Probable chromatin remodeling factor. (862 aa)
SYDChromatin structure-remodeling complex protein SYD; Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule d [...] (3574 aa)
CHR10Probable helicase CHR10; Probable helicase-like transcription factor. (877 aa)
CHR5Protein CHROMATIN REMODELING 5; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3 (By similarity). Probable chromatin remodeling factor. (1724 aa)
CHR7CHD3-type chromatin-remodeling factor CHR7; Chromatin remodeling factor that represses the expression of embryonic trait genes upon and after seed germination and thus enables the developmental switch to post-germinative growth. (1202 aa)
CHR4Protein CHROMATIN REMODELING 4; Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3 (By similarity). Probable chromatin remodeling factor. Belongs to the SNF2/RAD54 helicase family. (2223 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
IRX12Laccase-4; Lignin degradation and detoxification of lignin-derived products (By similarity). Required for secondary xylem cell wall lignification; Belongs to the multicopper oxidase family. (558 aa)
AS1Transcription factor AS1; Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis. Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development. [...] (367 aa)
LAC2Laccase-2; Lignin degradation and detoxification of lignin-derived products (By similarity). Required for root elongation in dehydration conditions; Belongs to the multicopper oxidase family. (573 aa)
TPS8Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8; In the N-terminal section; belongs to the glycosyltransferase 20 family. (856 aa)
LAC16Laccase-16; Lignin degradation and detoxification of lignin-derived products. (566 aa)
LAC3Laccase-3; Lignin degradation and detoxification of lignin-derived products. (570 aa)
BRMATP-dependent helicase BRM; ATPase subunit of a multiprotein complex equivalent of the SWI/SNF complex that acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. Represses embryonic genes in leaves and controls shoot development and flowering. Activates flower homeotic genes. The association of BRM with its target genes requires REF6. Necessary to acquire heat stress (HS) memory, by globally binding to HS memory genes. (2193 aa)
LAC10Laccase-10; Lignin degradation and detoxification of lignin-derived products. (558 aa)
TT10Laccase-15; Lignin degradation and detoxification of lignin-derived products (By similarity). Involved in lignin synthesis in seed coats, in seed coat permeability, in seed germination, and in root elongation. Required for the seed coat (testa) brown pigmentation by mediating the polymerization of proanthocyanidin (tannin) from its monomer precursor epicatechin. Slightly promotes seed dormancy. Belongs to the multicopper oxidase family. (565 aa)
CHR11ISWI chromatin-remodeling complex ATPase CHR11; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Involved in nuclear proliferation during megagametogenesis and cell expansion in the sporophyte. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key [...] (1056 aa)
BZR1Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2). (336 aa)
LAC11Laccase-11; Lignin degradation and detoxification of lignin-derived products. (557 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
LAC17Laccase-17; Lignin degradation and detoxification of lignin-derived products. (577 aa)
LAC12Laccase-12; Lignin degradation and detoxification of lignin-derived products. (565 aa)
LAC14Laccase-14; Lignin degradation and detoxification of lignin-derived products. (569 aa)
LAC9Laccase-9; Lignin degradation and detoxification of lignin-derived products. (586 aa)
TPS7Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7; In the N-terminal section; belongs to the glycosyltransferase 20 family. (851 aa)
LAC1Laccase-1; Lignin degradation and detoxification of lignin-derived products. (581 aa)
LAC13Laccase-13; Lignin degradation and detoxification of lignin-derived products. (569 aa)
PKLCHD3-type chromatin-remodeling factor PICKLE; Chromatin remodeling factor that represses the expression of embryonic trait genes (such as NFYB9/LEC1) upon and after seed germination and thus enables the developmental switch to post- germinative growth. Silences some MADS-box proteins such as PHE1 and PHE2. Plays a role during carpel differentiation. Regulates late processes in cytokinin signaling. (1384 aa)
LAC5Laccase-5; Lignin degradation and detoxification of lignin-derived products. (580 aa)
LAC7Laccase-7; Lignin degradation and detoxification of lignin-derived products. (567 aa)
DDM1ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa)
LAC6Laccase-6; Lignin degradation and detoxification of lignin-derived products; Belongs to the multicopper oxidase family. (569 aa)
CHR8Protein CHROMATIN REMODELING 8; Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation; Belongs to the SNF2/RAD54 helicase family. (1187 aa)
TPS11Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 11; In the C-terminal section; belongs to the trehalose phosphatase family. (862 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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