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AAP3 AAP3 TGA1 TGA1 AAP1 AAP1 UMAMIT28 UMAMIT28 CPK32 CPK32 NLP7 NLP7 AAP5 AAP5 PHL1 PHL1 NPC6 NPC6 NPC1 NPC1 NLP6 NLP6 CIPK23 CIPK23 NRG2 NRG2 ARF18 ARF18 COL7 COL7 BZIP1 BZIP1 ERF107 ERF107 LHT1 LHT1 LBD37 LBD37 HRS1 HRS1 HHO6 HHO6 NLP4 NLP4 NRT2.2 NRT2.2 TCP20 TCP20 CAT6 CAT6 UMAMIT29 UMAMIT29 AMT2 AMT2 NPC5 NPC5 NLP5 NLP5 STIPL1 STIPL1 ANR1 ANR1 IBH1 IBH1 LBD38 LBD38 AMT1-3 AMT1-3 NPC4 NPC4 LBD39 LBD39 AMT1-2 AMT1-2 HBI1 HBI1 TGA4 TGA4 SPT6 SPT6 IWS1 IWS1 NLP8 NLP8 AAP8 AAP8 UMAMIT14 UMAMIT14 NPC2 NPC2 CBL1 CBL1 NRT2.1 NRT2.1 NIA1 NIA1 AMT1-1 AMT1-1 RAV2 RAV2 AAP6 AAP6 CIPK15 CIPK15 NPF6.3 NPF6.3 AAP2 AAP2 KIN10 KIN10
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AAP3Amino acid permease 3; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for GABA, tryptophan and both neutral and basic amino acids. High affinity transport of cationic amino acids. (476 aa)
TGA1Transcription factor TGA1; Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'- TGACGTGG-3') another cis-acting element found in plant histone promoters; Belongs to the bZIP family. (368 aa)
AAP1Amino acid permease 1; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for histidine, glutamate and neutral amino acids. Reduced affinities for asparagine and valine. Involved in amino acid uptake from the apoplastic cavity into the embryo cells for storage protein accumulation and in root amino acid uptake. (485 aa)
UMAMIT28WAT1-related protein At1g01070; Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family. (365 aa)
CPK32Calcium-dependent protein kinase 32; May play a role in signal transduction pathways that involve calcium as a second messenger. Involved in maintaining Ca2+ homeostasis in pollen tube tips by regulating CNGC18. Functions as regulator of the calcium-mediated abscisic acid (ABA) signaling pathway. Phosphorylates ABA-responsive transcription factor ABF4 in vitro ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (538 aa)
NLP7Protein NLP7; Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. (959 aa)
AAP5Amino acid permease 5; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for glutamate and both neutral and basic amino acids. Reduced affinities for asparagine and valine. High affinity transport of the cationic amino acids arginine and lysine, but not of histidine. (480 aa)
PHL1Protein PHR1-LIKE 1; Transcription factor acting as central integrator of phosphate starvation responses. Regulates FER1 expression upon phosphate starvation, linking iron and phosphate homeostasis ; Belongs to the MYB-CC family. (413 aa)
NPC6Non-specific phospholipase C6. (520 aa)
NPC1Non-specific phospholipase C1. (533 aa)
NLP6Protein NLP6; Probable transcription factor. (841 aa)
CIPK23CBL-interacting serine/threonine-protein kinase 23; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium-dependent manner. Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells. In response to low nitrate concentration, phosphorylates NRT1.1, switching it fr [...] (482 aa)
NRG2Nitrate regulatory gene2 protein; Required for nitrate signaling. Regulates expression of the nitrate-responsive genes NIA1, NIR1, NRT2.1 and NPF6.3/NRT1.1. (796 aa)
ARF18Auxin response factor 18; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. (602 aa)
COL7Zinc finger protein CONSTANS-LIKE 7. (392 aa)
BZIP1Basic leucine zipper 1; Transcription factor that binds to the C-box-like motif (5'- TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling. Activated by low energy stress both at transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark- induced starvation response. Transcription activator of the mannan synthase CSLA9. Recognizes and binds to DNA-specific sequence of CSLA9 promoter. Belongs to the bZIP [...] (145 aa)
ERF107Ethylene-responsive transcription factor ERF107; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity); Belongs to the AP2/ERF transcription factor family. ERF subfamily. (201 aa)
LHT1Lysine histidine transporter 1; Amino acid-proton symporter. Transporter with a broad specificity for histidine, lysine, glutamic acid, alanine, serine, proline and glycine. Involved in both apoplastic transport of amino acids in leaves and their uptake by roots. Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily. (446 aa)
LBD37LOB domain-containing protein 37. (250 aa)
HRS1Transcription factor HRS1; Transcription factor involved in nitrate and phosphate signaling in roots. Integrates nitrate and phosphate starvation responses and adaptation of root architecture depending on nutrient availabilities. Acts downstream of the nitrate sensor and transporter NPF6.3/NRT1.1. Represses primary root development in response to phosphate deficiency conditions, only when nitrate is present. Involved in the modulation of primary root and root hair growth in phosphate-deprived environement. May be required for suppressing abscisic acid (ABA) signaling in germinating emb [...] (344 aa)
HHO6Transcription factor HHO6; Probable transcription factor involved in phosphate signaling in roots. (333 aa)
NLP4Protein NLP4; Probable transcription factor. (844 aa)
NRT2.2High-affinity nitrate transporter 2.2; Involved in high-affinity nitrate transport. (522 aa)
TCP20Transcription factor TCP20; Transcription factor that binds to the site II motif (3'- TGGGCC/T-5') in the promoter of PCNA-2 and to 3'-GCCCG/A-5' elements in the promoters of cyclin CYCB1-1 and ribosomal protein genes. (314 aa)
CAT6Cationic amino acid transporter 6, chloroplastic; Permease involved in the transport of the cationic neutral or acidic amino acids. (583 aa)
UMAMIT29WAT1-related protein At4g01430; Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family. (365 aa)
AMT2Ammonium transporter 2; High affinity ammonium transporter that may play an important role in moving ammonium between the apoplast and symplast of cells throughout the plant. Does not transport methylammonium. Belongs to the ammonia transporter channel (TC 1.A.11.2) family. (475 aa)
NPC5Non-specific phospholipase C5; Non-specific phospholipase C (PLC) which assumes minor PLC activity during inorganic phosphate starvation. Can hydrolyze both phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Required for normal accumulation of digalactosyldiacylglycerol (DGDG) during phosphate limitation and may contribute to the conversion of phospholipids to diacylglycerol, the substrate for galactolipid synthesis. (521 aa)
NLP5Protein NLP5; Probable transcription factor. (808 aa)
STIPL1Septin and tuftelin-interacting protein 1 homolog 1; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events (By similarity). Involved in snRNPs recycling. Required for efficient splicing of genes that act within the plant circadian clock. Part of a transcription elongation checkpoint at alternative exons. Required for correct expression and splicing of DOG1, a regulator of seed dormancy. May induce transient transcriptional pausing of polymerase II at slices sites. (849 aa)
ANR1MADS-box transcription factor ANR1; Probable transcription factor. Required for root plasticity in response to nitrate, NO(3)(-). Promotes lateral root growth in a NRT1.1-dependent manner. (234 aa)
IBH1Transcription factor IBH1; Atypical and probable non DNA-binding bHLH transcription factor that acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling. Is able to form heterodimer with BHLH49, thus inhibiting DNA binding of BHLH49, which is a transcriptional activator that regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds and inhibits HBI1, a positive regulator of cell elongation that directly binds to the promoters and activated [...] (156 aa)
LBD38LOB domain-containing protein 38; Belongs to the LOB domain-containing protein family. (247 aa)
AMT1-3Ammonium transporter 1 member 3; Ammonium transporter probably involved in ammonium uptake from the soil. Contributes with AMT1-1 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions. (498 aa)
NPC4Non-specific phospholipase C4; Non-specific phospholipase C (PLC) which assumes major PLC activity during inorganic phosphate starvation. Substrate preference is phosphatidylcholine (PC), but can also hydrolyze phosphatidylethanolamine (PE) with lower efficiency. Has no activity toward phosphatidic acid (PA). Plays an important role in the supply of both inorganic phosphate and diacylglycerol from membrane-localized phospholipids during phosphate deprivation. May be required for lipid- derived signaling molecules that positively modulate abscisic acid (ABA) response and promote plant t [...] (538 aa)
LBD39LOB domain-containing protein 39. (240 aa)
AMT1-2Ammonium transporter 1 member 2; Ammonium transporter probably involved in ammonium uptake from the soil. (514 aa)
HBI1Transcription factor HBI1; Atypical bHLH transcription factor that acts as positive regulator of cell elongation downstream of multiple external and endogenous signals by direct binding to the promoters and activation of the two expansin genes EXPA1 and EXPA8, encoding cell wall loosening enzymes. Transcriptional activity is inhibited when binding to the bHLH transcription factor IBH1. (337 aa)
TGA4Transcription factor TGA4; Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'- TGACGTGG-3') another cis-acting element found in plant histone promoters. (364 aa)
SPT6Transcription elongation factor SPT6 homolog; Transcription elongation factor that enhances the transcription elongation by RNA polymerase II (RNAPII) (By similarity). Plays an important role in regulating embryo apical and basal patterning during early embryogenesis, partly through negative regulation of the transcription factors PHABULOSA and PHAVOLUTA. Belongs to the SPT6 family. (1647 aa)
IWS1Protein IWS1 homolog 1; Transcription factor involved in RNA polymerase II (RNAPII) transcription regulation. Involved in transcription elongation. May function at post-recruitment and elongation steps of transcription. May be recruited by BZR2/BES1 to target genes and promote their expression during transcription elongation process. Required for brassinosteroid (BR)-induced gene expression. Required the for regulation of numerous nitrogen-responsive genes in roots. Acts in roots to repress NRT2.1 transcription in response to high nitrogen supply. This repression is associated with an [...] (502 aa)
NLP8Protein NLP8; Probable transcription factor. (947 aa)
AAP8Amino acid permease 8; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for glutamate, aspartate and neutral and acidic amino acids; Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily. (475 aa)
UMAMIT14WAT1-related protein At2g39510. (374 aa)
NPC2Non-specific phospholipase C2. (514 aa)
CBL1Calcineurin B-like protein 1; Acts as a calcium sensor involved in the signaling pathway during growth and development and in response to abiotic stresses. May function as a positive regulator of salt and drought responses and as a negative regulator of cold response. Contributes to the regulation of early stress-related CBF/DREB transcription factors. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 [...] (213 aa)
NRT2.1High-affinity nitrate transporter 2.1; Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NTR3.1. Acts as a repressor of lateral root initiation under high sucrose/low nitrate conditions. (530 aa)
NIA1Nitrate reductase [NADH] 1; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (917 aa)
AMT1-1Ammonium transporter 1 member 1; High affinity ammonium transporter probably involved in ammonium uptake from the soil, long-distance transport to the shoots and re-uptake of apoplastic ammonium that derives from photorespiration in shoots. Contributes with AMT1-3 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions. Belongs to the ammonia transporter channel (TC 1.A.11.2) family. (501 aa)
RAV2AP2/ERF and B3 domain-containing transcription repressor RAV2; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional repressor of flowering time on long day plants. Acts directly on FT expression by binding 5'-CAACA-3' and 5'-CACCTG-3 sequences (Probable). Functionally redundant with TEM1. (352 aa)
AAP6Amino acid permease 6; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for tryptophan, proline, and neutral and acidic amino acids. Has an affinity for aspartate in a physiological range. Involved in the uptake of amino acids diffusing out of the xylem tracheids into the xylem parenchyma. (481 aa)
CIPK15CBL-interacting serine/threonine-protein kinase 15; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. (421 aa)
NPF6.3Protein NRT1/ PTR FAMILY 6.3; Dual affinity nitrate transporter. Involved in proton- dependent nitrate uptake and in the regulation of the nitrate transporter NRT2.1. Acts also as a nitrate sensor that trigger a specific signaling pathway stimulating lateral root growth and seed germination. The uptake activity is not required for sensor function. Displays an auxin transport facilitation inhibited by high nitrate concentration. Required to prevent auxin accumulation in preemerged lateral root primordia and young lateral roots when external nitrate concentration is low or null. May be i [...] (590 aa)
AAP2Amino acid permease 2; Amino acid-proton symporter. Stereospecific transporter with a broad specificity for histidine, arginine, glutamate and neutral amino acids, favoring small amino acids such as alanine, asparagine and glutamine. Accepts also large aromatic residues such as in phenlalanine or tyrosine. Has a much higher affinity for basic amino acids as compared with AAP1. May function in xylem-to-phloem transfer and in uptake of amino acids assimilated in the green silique tissue. Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18 [...] (493 aa)
KIN10SNF1-related protein kinase catalytic subunit alpha KIN10; Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, a central regulator of cellular energy homeostasis, which, in response to seemingly unrelated darkness, sugar and stress conditions, activates energy-producing pathways and inhibits energy-consuming processes. May play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA c [...] (512 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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