STRINGSTRING
T13E15.16 T13E15.16 CLE26 CLE26 PID PID BRX BRX PIP5K1 PIP5K1 CLE45 CLE45 CLE41 CLE41 BRXL2 BRXL2 PIP5K2 PIP5K2 PBS1 PBS1 D6PK D6PK MAKR5 MAKR5 CLE9 CLE9 IP5P6 IP5P6 CLV3 CLV3 PDPK1 PDPK1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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T13E15.16Protein kinase superfamily protein. (765 aa)
CLE26CLAVATA3/ESR (CLE)-related protein 26; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (118 aa)
PIDProtein kinase PINOID; Serine/threonine-protein kinase involved in the regulation of auxin signaling. Acts as a positive regulator of cellular auxin efflux and regulates organ development by enhancing polar auxin transport. Phosphorylates conserved serine residues in the PIN auxin efflux carriers. Phosphorylation of PIN proteins is required and sufficient for apical-basal PIN polarity that enables directional intercellular auxin fluxes, which mediate differential growth, tissue patterning and organogenesis. Acts in association with PIN1 to control the establishment of bilateral symmetr [...] (438 aa)
BRXProtein BREVIS RADIX; Acts as a regulator of cell proliferation and elongation in the root and shoot. Regulates roots architecture and primary root protophloem differentiation. Probable transcription regulator. Regulated by the auxin response factor ARF5. Polarly localized in vascular cells and subject to endocytic recycling. Required for CPD expression and for correct nuclear auxin response. Mediates cross-talk between the auxin and brassinosteroid pathways. BRX is a target for auxin-induced, proteasome-mediated degradation. (344 aa)
PIP5K1Phosphatidylinositol 4-phosphate 5-kinase 1; Catalyzes the synthesis of phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4-bisphosphate. (752 aa)
CLE45CLAVATA3/ESR (CLE)-related protein 45; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Prevents, in a dose-dependent manner, auxin response in the root meristem thus leading in the repression of protophloem differentiation and periclinal sieve element precursor cell division. (124 aa)
CLE41CLAVATA3/ESR (CLE)-related protein 41; Extracellular signal peptide that regulates cell fate. May act with TDR as a ligand-receptor pair in a signal transduction pathway that represses tracheary element differentiation but promotes the formation of procambial cells adjacent to phloem cells in the veins in an auxin-dependent manner. (99 aa)
BRXL2Protein Brevis radix-like 2. (374 aa)
PIP5K2Phosphatidylinositol 4-phosphate 5-kinase 2; Possesses phosphatidylinositol kinase activity in vitro. (754 aa)
PBS1Serine/threonine-protein kinase PBS1; Protein kinase required for plant defense mechanism mediated by the disease resistance (R) protein RPS5. In case of infection by Pseudomonas syringae, AvrPphB triggers RPS5-mediated defense mechanism via the cleavage of PBS1. Both kinase activity and cleavage by avrPphB are independently required to trigger the RPS5-mediated resistance. Contributes to PAMP-triggered immunity (PTI) signaling and defense responses downstream of FLS2. (456 aa)
D6PKSerine/threonine-protein kinase D6PK; Protein kinase that regulates the auxin transport activity of PIN auxin efflux facilitators by direct phosphorylation. D6PK-mediated PIN phosphorylation promotes auxin transport in the hypocotyl and this is a prerequisite for PHOT1-dependent hypocotyl bending. Phosphorylates PIN1, PIN2, PIN3, PIN4 and PIN7 in vitro and PIN1 in vivo. (498 aa)
MAKR5Probable membrane-associated kinase regulator 5. (326 aa)
CLE9CLAVATA3/ESR (CLE)-related protein 9; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (120 aa)
IP5P6Type IV inositol polyphosphate 5-phosphatase 6; Has phosphatase activity toward PtdIns(4,5)P2 and PtdIns(3,4,5)P3. Required for the patterning of procambium and during the differentiation of vascular tissues. Acts before the acquisition of preprocambial identity. Seems to be also involved in the abscisic acid (ABA) signaling pathway. Acts redundantly with CVL1 for maintaining vascular continuity. Regulates phosphoinositide-dependent VAN3 localization. Belongs to the inositol polyphosphate 5-phosphatase family. (617 aa)
CLV3Protein CLAVATA 3; Extracellular signal that regulates meristem maintenance. Acts with CLV1 as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the CLV3/ESR signal peptide family. (96 aa)
PDPK13-phosphoinositide-dependent protein kinase 1; May couple lipid signals to the activation-loop phosphorylation of several protein kinases of the so-called AGC kinase family. Interacts via its pleckstrin homology domain with phosphatidic acid, PtdIns3P and PtdIns(3,4)P2 and to a lesser extent with PtdIns(4,5)P2 and PtdIns4P. May play a general role in signaling processes controlling the pathogen/stress response, polar auxin transport and development. Transphosphorylates the AGC protein kinases OXI1/AGC2-1, PK1/S6K1, PK19/S6K2 and PID resulting in their activation. (491 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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