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NPC1 NPC1 PLIP2 PLIP2 LPLAT1 LPLAT1 SQD1 SQD1 NPC2 NPC2 FAD2 FAD2 FAD3 FAD3 ATS1 ATS1 LIP1-2 LIP1-2 PLIP1 PLIP1 NPC6 NPC6 LPEAT2 LPEAT2 WSD1 WSD1 ADS3 ADS3 DGAT3 DGAT3 LPLAT2 LPLAT2 GPC1 GPC1 PDAT1 PDAT1 PDAT2 PDAT2 ROD1 ROD1 NPC5 NPC5 PGD1 PGD1 NPC4 NPC4 FATA2 FATA2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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NPC1Non-specific phospholipase C1. (533 aa)
PLIP2Phospholipase A1 PLIP2, chloroplastic; Sn-1-specific phospholipase A1 that catalyzes the initial step of oxylipins and jasmonate (JA) biosynthesis. Hydrolyzes polyunsaturated acyl groups preferentially from chloroplastic monogalactosyldiacylglycerol (MGDG). May function downstream of abscisic acid (ABA) and provide a link between ABA-mediated abiotic stress responses and oxylipin and JA signalings. In vitro, possesses broad substrate specificity. Can hydrolyze the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), the sulfolipid sulfoquinovosyldiac [...] (713 aa)
LPLAT1Lysophospholipid acyltransferase 1; Lysophospholipid acyltransferase with broad specificity. Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn- glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn- glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl- sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphati [...] (462 aa)
SQD1UDP-sulfoquinovose synthase, chloroplastic; Involved in the biosynthesis of sulfolipids found in thylakoid membranes. Converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (477 aa)
NPC2Non-specific phospholipase C2. (514 aa)
FAD2Delta(12)-fatty-acid desaturase; ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. Delta(12)-desaturase with regioselectivity determined by the double bond (delta(9) position) and carboxyl group of the substrate. Can use both 16:1 and 18:1 fatty acids as substrates. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine (PC) and, possibly, other phospholipids. Very low constitutive hydroxylation activity. Required [...] (383 aa)
FAD3Acyl-lipid omega-3 desaturase (cytochrome b5), endoplasmic reticulum; Microsomal (ER) omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine and, possibly, other phospholipids. (386 aa)
ATS1Glycerol-3-phosphate acyltransferase, chloroplastic; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate. The enzyme from chilling-resistant plants discriminates against non-fluid palmitic acid and selects oleic acid whereas the enzyme from sensitive plants accepts both fatty acids. This is an oleate-selective acyltransferase. (459 aa)
LIP1-2Triacylglycerol lipase 1; Triacylglycerol (TAG) lipase active on triolein, trioctanoin, tributyrin and 1,3-Diolein, but not on phospho- and galactolipids. May be involved but dispensable for TAG storage breakdown during seed germination. (393 aa)
PLIP1Phospholipase A1 PLIP1, chloroplastic; Sn-1-specific phospholipase A1 involved in seed oil biosynthesis. Hydrolyzes polyunsaturated acyl groups from a unique chloroplast-specific phosphatidylglycerol (PG) that contains 16:1 delta 3-trans as its second acyl group. The polyunsaturated acyl groups released by PLIP1 are exported from the chloroplast, reincorporated into phosphatidylcholine (PC), and ultimately enter seed triacylglycerol (TAG). In vitro, possesses broad substrate specificity. Can hydrolyze the galactolipid monogalactosyldiacylglycerol (MGDG), and the phoshpolipids phosphati [...] (649 aa)
NPC6Non-specific phospholipase C6. (520 aa)
LPEAT2Lysophospholipid acyltransferase LPEAT2; Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates. Exhibits strong acylation activity of lysophosphatidylethanolamine (LPE) and lower activity on lysophosphatidate (LPA). Has a preference for 18:1- LPE over 16:0-LPE as acceptor and palmitoyl-CoA (16:0-CoA) as acyl donor. Activity is calcium-independent. (539 aa)
WSD1O-acyltransferase WSD1; Bifunctional wax ester synthase/diacylglycerol acyltransferase. Involved in cuticular wax biosynthesis. In the N-terminal section; belongs to the long-chain O- acyltransferase family. (481 aa)
ADS3Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic; Fatty acid desaturase involved in the first desaturation step leading to the formation of hexadeca 7,10,13-trienoic acid (16:3(7Z,10Z,13Z)), the major functional components of thylakoid membranes. Required for chloroplast biogenesis at low temperature. Also indirectly involved in the production of the oxylipin dinor-oxo-phyto- dienoic acid implicated in wound signaling. (371 aa)
DGAT3Diacylglycerol O-acyltransferase 3; Involved in triacylglycerol (TAG) biosynthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. May preferentially use linolenoyl-CoA as substrate and to a lesser extent linoleoyl-CoA. May contribute to the active recycling of linoleate and linolenate into TAG when seed oil breakdown is blocked. (360 aa)
LPLAT2Lysophospholipid acyltransferase 2; Lysophospholipid acyltransferase with broad specificity. Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn- glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn- glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl- sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphati [...] (465 aa)
GPC1Glycerophosphocholine acyltransferase 1; Glycerophosphocholine acyltransferase (GPCAT) that utilizes acyl-CoA to acylate glycero-3-phosphocholine (GPC), forming lysophosphatidylcholine (LPC). Shows broad acyl specificities with a preference for 16:0-CoA, polyunsaturated acyl-CoA, and the hydroxylated ricinoleoyl-CoA. Catalyzes also the acylation of glycero-3-phosphoethanolamine (GPE) with acyl-CoA. In addition to acyl-CoA, GPCAT efficiently utilizes LPC and lysophosphatidylethanolamine (LPE) as acyl donors in the acylation of GPC. Contributes to the maintenance of phosphatidylcholine ( [...] (381 aa)
PDAT1Phospholipid:diacylglycerol acyltransferase 1; Triacylglycerol formation by an acyl-CoA independent pathway. The enzyme preferentially transfers acyl groups from the sn-2 position of a phospholipid to diacylglycerol, thus forming an sn-1- lysophospholipid. Involved in epoxy and hydroxy fatty acid accumulation in seeds. Has complementary functions with DAG1 that are essential for triacylglycerol synthesis and normal development of both seeds and pollen. (671 aa)
PDAT2Putative phospholipid:diacylglycerol acyltransferase 2; Belongs to the AB hydrolase superfamily. Lipase family. (665 aa)
ROD1Phosphatidylcholine:diacylglycerol cholinephosphotransferase 1; Functions as phosphatidylcholine:diacylglycerol cholinephosphotransferase that catalyzes the transfer of the phosphocholine headgroup from phosphatidylcholine (PC) to diacylglycerol, a major reaction for the transfer of 18:1 into phosphatidylcholine for desaturation and also for the reverse transfer of 18:2 and 18:3 into the triacylglycerols synthesis pathway. (301 aa)
NPC5Non-specific phospholipase C5; Non-specific phospholipase C (PLC) which assumes minor PLC activity during inorganic phosphate starvation. Can hydrolyze both phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Required for normal accumulation of digalactosyldiacylglycerol (DGDG) during phosphate limitation and may contribute to the conversion of phospholipids to diacylglycerol, the substrate for galactolipid synthesis. (521 aa)
PGD16-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
NPC4Non-specific phospholipase C4; Non-specific phospholipase C (PLC) which assumes major PLC activity during inorganic phosphate starvation. Substrate preference is phosphatidylcholine (PC), but can also hydrolyze phosphatidylethanolamine (PE) with lower efficiency. Has no activity toward phosphatidic acid (PA). Plays an important role in the supply of both inorganic phosphate and diacylglycerol from membrane-localized phospholipids during phosphate deprivation. May be required for lipid- derived signaling molecules that positively modulate abscisic acid (ABA) response and promote plant t [...] (538 aa)
FATA2Oleoyl-acyl carrier protein thioesterase 2, chloroplastic; Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for oleoyl- ACP versus other acyl-ACPs. (367 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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