STRINGSTRING
BLH10 BLH10 KNATM KNATM AS2 AS2 BLH6 BLH6 AS1 AS1 LBD30 LBD30 KNAT1 KNAT1 KNAT2 KNAT2 KNAT3 KNAT3 KNAT4 KNAT4 KNAT5 KNAT5 BEL1 BEL1 KNAT6 KNAT6 BLH5 BLH5 KNAT7 KNAT7 BLH3 BLH3 BLH1 BLH1 BLH8 BLH8 ABI5 ABI5 BLH2 BLH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BLH10BEL1-like homeodomain protein 10; Belongs to the TALE/BELL homeobox family. (538 aa)
KNATMProtein KNATM; [Isoform KNATM-B]: Transcriptional regulator involved in leaf proximal/distal patterning. May act by sequestering BELL transcription factors. (142 aa)
AS2Protein ASYMMETRIC LEAVES 2; Negative regulator of cell proliferation in the adaxial side of leaves. Regulates the formation of a symmetric lamina and the establishment of venation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 1 (AS1) to repress the knox homeobox genes KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3, KAN2 and YAB5. May act in parallel with the RDR6- SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis. [...] (199 aa)
BLH6BEL1-like homeodomain protein 6; Belongs to the TALE/BELL homeobox family. (532 aa)
AS1Transcription factor AS1; Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis. Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development. [...] (367 aa)
LBD30LOB domain-containing protein 30; Involved in the positive regulation of tracheary element (TE) differentiation. Involved in a positive feedback loop that maintains or promotes NAC030/VND7 expression that regulates TE differentiation- related genes; Belongs to the LOB domain-containing protein family. (228 aa)
KNAT1Homeobox protein knotted-1-like 1; May play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state, and its expression disappears at the same time the shoot apex undergoes the transition from vegetative to reproductive development. Positive regulator of LATERAL ORGAN BOUNDARIES (LOB). Probably binds to the DNA sequence 5'-TGAC-3'. Able to traffic from the L1 to the L2/L3 layers of the meristem, presumably through plasmodesmata. Belongs to the TALE/KNOX homeobox family. (398 aa)
KNAT2Homeobox protein knotted-1-like 2; May play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. (310 aa)
KNAT3Homeobox protein knotted-1-like 3; Belongs to the TALE/KNOX homeobox family. (431 aa)
KNAT4Homeobox protein knotted-1-like 4; Belongs to the TALE/KNOX homeobox family. (393 aa)
KNAT5Homeobox protein knotted-1-like 5. (383 aa)
BEL1Homeobox protein BEL1 homolog; Plays a major role in ovule patterning and in determination of integument identity via its interaction with MADS-box factors. Formation of complex with AG-SEP dimers negatively regulates the carpel identity process and favors the maintenance of ovule identity. BEL1-STM complex maintains the indeterminacy of the inflorescence meristem. Required, with SPL, for cytokinin-induced PIN1 expression in ovules. (611 aa)
KNAT6Homeobox protein knotted-1-like 6; Plays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. Belongs to the TALE/KNOX homeobox family. (327 aa)
BLH5BEL1-like homeodomain protein 5. (431 aa)
KNAT7Homeobox protein knotted-1-like 7; May be involved in secondary cell wall biosynthesis. (291 aa)
BLH3BEL1-like homeodomain protein 3; Transcription factor that is responsive of the nuclear import of SHOOT MERISTEMLESS (STM). (524 aa)
BLH1BEL1-like homeodomain protein 1; Belongs to the TALE/BELL homeobox family. (680 aa)
BLH8BEL1-like homeodomain protein 8; Required for specifying floral primordia and establishing early internode patterning events during inflorescence development. Belongs to the TALE/BELL homeobox family. (584 aa)
ABI5Protein ABSCISIC ACID-INSENSITIVE 5; Participates in ABA-regulated gene expression during seed development and subsequent vegetative stage by acting as the major mediator of ABA repression of growth. Binds to the embryo specification element and the ABA-responsive element (ABRE) of the Dc3 gene promoter and to the ABRE of the Em1 and Em6 genes promoters. Can also trans- activate its own promoter, suggesting that it is autoregulated. Plays a role in sugar-mediated senescence. Belongs to the bZIP family. ABI5 subfamily. (442 aa)
BLH2BEL1-like homeodomain protein 2; Transcription factor that establishes leaf shape by repressing growth in specific subdomains of the leaf. Negatively regulates knox homeobox gene KNAT1/BP expression. (739 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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