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PIF4 | Transcription factor PIF4; Transcription factor acting negatively in the phytochrome B signaling pathway. May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif (By similarity). Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light). Belongs to the bHLH protein family. (430 aa) | ||||
MYB23 | Transcription factor MYB23; Transcription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Regulates the epidermal cell fate specification. Mediates the formation of columellae and accumulation of mucilages on seed coats. Controls the elongation of epidermal cells positively in roots but negatively in stems, leading to the promotion of primary roots elongation and repression of leaves and stems elongation, respectively. Ovoids ectopic root-hair formation, probably by inducing GL2 in roots. Controls trichome initiation and branching. (219 aa) | ||||
BHLH2 | Transcription factor EGL1; Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation but promotes trichome formation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell formation. Seems also to play a role in the activation of anthocyanin biosynthesis, probably together with MYB75/PAP1. Involve [...] (596 aa) | ||||
MYB75 | Transcription factor MYB75; Transcription activator, when associated with BHLH12/MYC1, EGL3, or GL3. Promotes the synthesis of. phenylpropanoid-derived compounds such as anthocyanins and proanthocyanidin, probably together with GL3 and BHLH2. Regulates the expression of CHS, DFRA, LDOX, and BAN. (248 aa) | ||||
HEC1 | Transcription factor HEC1; Required for the female reproductive tract development and fertility. (241 aa) | ||||
MYC3 | Transcription factor MYC3; Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (592 aa) | ||||
TT2 | Transcription factor TT2; Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). (258 aa) | ||||
GL3 | Transcription factor GLABRA 3; Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation, but, in association with TTG1 and MYB0/GL1, promotes trichome formation, branching and endoreplication. Regulates also trichome cell wall maturation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell form [...] (637 aa) | ||||
MYB114 | Transcription factor MYB114; Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8. (139 aa) | ||||
MYB113 | Transcription factor MYB113; Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8. (246 aa) | ||||
TT8 | Transcription factor TT8; Transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2. Involved in the control of flavonoid pigmentation. Plays a key role in regulating leucoanthocyanidin reductase (BANYULS) and dihydroflavonol-4-reductase (DFR). Not required for leucoanthocyanidin dioxygenase (LDOX) expression. (518 aa) | ||||
SPT | Transcription factor SPATULA; Transcription factor that plays a role in floral organogenesis. Promotes the growth of carpel margins and of pollen tract tissues derived from them. (373 aa) | ||||
TOZ | Transducin family protein / WD-40 repeat family protein. (876 aa) | ||||
UGT78D2 | Flavonol 3-O-glucosyltransferase; Flavonol 3-O-glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to the 3-OH position of quercetin and kaempferol. Possesses high quercetin 3-O-glucosyltransferase activity in vitro. Catalyzes the glycosylation of anthocyanins from UDP-glucose. Also active in vitro on benzoates and benzoate derivatives. Belongs to the UDP-glycosyltransferase family. (460 aa) | ||||
SCRM2 | Transcription factor SCREAM2; Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation. (450 aa) | ||||
SCRM | Transcription factor ICE1; Transcriptional activator that regulates the cold-induced transcription of CBF/DREB1 genes. Binds specifically to the MYC recognition sites (5'-CANNTG-3') found in the CBF3/DREB1A promoter. Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation. (494 aa) | ||||
WAG2 | Serine/threonine-protein kinase WAG2; Serine/threonine-protein kinase involved in the regulation of auxin signaling. Acts as a positive regulator of cellular auxin efflux and regulates organ development by enhancing PIN-mediated polar auxin transport. Phosphorylates conserved serine residues in the PIN auxin efflux carriers. Phosphorylation of PIN proteins is required and sufficient for apical-basal PIN polarity that enables directional intercellular auxin fluxes, which mediate differential growth, tissue patterning and organogenesis. Acts as suppressors of root waving. (480 aa) | ||||
A3G2XYLT | Anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase; Contributes to the last few anthocyanin biosynthetic steps. Converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1->2)glucoside. Can use 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose as substrates. (468 aa) | ||||
MUTE | Transcription factor MUTE; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. (202 aa) | ||||
CYP75B1 | Flavonoid 3'-monooxygenase; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Convert naringenin to eriodictyol and dihydrokaempferol to dihydroquercetin; Belongs to the cytochrome P450 family. (513 aa) | ||||
EPFL9 | EPIDERMAL PATTERNING FACTOR-like protein 9; [Stomagen]: Positively regulates stomatal density and patterning. Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily. (102 aa) | ||||
YAB3 | Axial regulator YABBY 3; Involved in the abaxial cell fate determination during embryogenesis and organogenesis. Regulates the initiation of embryonic shoot apical meristem (SAM) development. Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems. Binds DNA without sequence specificity. Belongs to the YABBY family. (240 aa) | ||||
TTG1 | Protein TRANSPARENT TESTA GLABRA 1; May regulate MYC transcription factors. Involved in epidermal cell fate specification such as trichome and root hair development, seed mucilage production, and anthocyanin biosynthesis by acting at the dihydroflavonol-4-reductase (DFR) step. Together with GL1 and GL3, promotes trichome formation. Activates the transcription of GL2. (341 aa) | ||||
ARR11 | Two-component response regulator ARR11; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins (By similarity); Belongs to the ARR family. Type-B subfamily. (521 aa) | ||||
HY5 | Transcription factor HY5; Transcription factor that promotes photomorphogenesis in light. Acts downstream of the light receptor network and directly affects transcription of light-induced genes. Specifically involved in the blue light specific pathway, suggesting that it participates in transmission of cryptochromes (CRY1 and CRY2) signals to downstream responses. In darkness, its degradation prevents the activation of light-induced genes (Probable). Acts coordinately with SPL7 to regulate the microRNA miR408 and its target genes in response to changes in light and copper conditions. R [...] (168 aa) | ||||
MYC4 | Transcription factor MYC4; Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA- dependent responses. Can form complexes with all known glucosinolate- related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (589 aa) | ||||
PIF3 | Transcription factor PIF3; Transcription factor acting positively in the phytochrome signaling pathway. Activates transcription by binding to the G box (5'- CACGTG-3'). (524 aa) | ||||
AGL5 | Agamous-like MADS-box protein AGL5; Probable transcription factor. Interacts genetically with TT16/AGL32 in a partially antagonistic manner during flower development. Is essential for the coordination of cell divisions in ovule, seed coat development and endosperm formation. (246 aa) | ||||
GL2 | Homeobox-leucine zipper protein GLABRA 2; Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. (747 aa) | ||||
DFRA | Dihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (382 aa) | ||||
ARF5 | Auxin response factor 5; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. (902 aa) | ||||
MYC2 | Transcription factor MYC2; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the prom [...] (623 aa) | ||||
FAMA | Transcription factor FAMA; Transcription activator. Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity. Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata. Prevents histone H3K27me3 marks and derepresses stem cell gene expression. (414 aa) | ||||
SPCH | Transcription factor SPEECHLESS; Transcription factor acting as an integration node for stomata and brassinosteroid (BR) signaling pathways to control stomatal initiation and development. Activates transcription when in the presence of SCRM/ICE1. Functions as a dimer with SCRM or SCRM2 during stomatal initiation. Required for the initiation, the spacing and the formation of stomata, by promoting the first asymmetric cell divisions. Together with FMA and MUTE, modulates the stomata formation. Involved in the regulation of growth reduction under osmotic stress (e.g. mannitol), associated [...] (364 aa) | ||||
PIF5 | Transcription factor PIF5; Transcription factor acting negatively in the phytochrome B signaling pathway to promote the shade-avoidance response. Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin-proteasome pathway. Promotes ethylene activity in the dark. May regulate the expression of a subset of genes by binding to the G- box motif. Might be involved in the integration of light-signals to control both circadian and photomorphogenic processes. Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box var [...] (444 aa) | ||||
BEE1 | Transcription factor BEE 1; Positive regulator of brassinosteroid signaling. (260 aa) | ||||
ARR14 | Two-component response regulator ARR14; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins (By similarity); Belongs to the ARR family. Type-B subfamily. (382 aa) | ||||
EPF2 | Protein EPIDERMAL PATTERNING FACTOR 2; Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERECTA as major receptor. Inactivated by cleavage by CRSP (AC Q9LNU1). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). (120 aa) | ||||
EPF1 | Protein EPIDERMAL PATTERNING FACTOR 1; Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1). MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERL1 as major receptor. May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily. (104 aa) | ||||
BHLH12 | Transcription factor MYC1; Trancsription activator, when associated with MYB75/PAP1 or MYB90/PAP2. (526 aa) |