STRINGSTRING
RFS2 RFS2 SWI2 SWI2 CHR10 CHR10 CHR5 CHR5 CHR4 CHR4 GOLS1 GOLS1 ERD7 ERD7 GOLS3 GOLS3 HSFA2 HSFA2 HSP18.1 HSP18.1 COR47 COR47 HSP21 HSP21 RD29A RD29A RD22 RD22 HSFA6A HSFA6A APX2 APX2 IPS2 IPS2 RFS1 RFS1 RFS6 RFS6 NAC072 NAC072 ZAT10 ZAT10 HSFB1 HSFB1 RFS5 RFS5 GOLS2 GOLS2 EGY3 EGY3 HSFA1D HSFA1D HSFA6b HSFA6b HSFA9 HSFA9 PKL PKL HSP70-5 HSP70-5 WRKY1 WRKY1 HSP26.5 HSP26.5 RFS4 RFS4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RFS2Probable galactinol--sucrose galactosyltransferase 2; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity); Belongs to the glycosyl hydrolases 36 family. (773 aa)
SWI2Switch 2; May be involved in early DNA damage response (By similarity). Probable chromatin remodeling factor. (862 aa)
CHR10Probable helicase CHR10; Probable helicase-like transcription factor. (877 aa)
CHR5Protein CHROMATIN REMODELING 5; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3 (By similarity). Probable chromatin remodeling factor. (1724 aa)
CHR4Protein CHROMATIN REMODELING 4; Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3 (By similarity). Probable chromatin remodeling factor. Belongs to the SNF2/RAD54 helicase family. (2223 aa)
GOLS1Galactinol synthase 1; Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. Promotes plant stress tolerance such as heat, chilling, salinity and methylviologen (MV), a superoxide radical generating drug, by mediating raffinose accumulation, an osmoprotective substance. (344 aa)
ERD7Protein EARLY-RESPONSIVE TO DEHYDRATION 7, chloroplastic. (452 aa)
GOLS3Galactinol synthase 3; Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance (By similarity). (334 aa)
HSFA2Heat stress transcription factor A-2; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). Belongs to the HSF family. Class A subfamily. (345 aa)
HSP18.118.1 kDa class I heat shock protein. (161 aa)
COR47Dehydrin COR47. (265 aa)
HSP21Heat shock protein 21, chloroplastic; Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. Belongs to the small heat shock protein (HSP20) family. (227 aa)
RD29ALow-temperature-induced 78 kDa protein; Involved in responses to abiotic stresses. Regulates probably root elongation in cold conditions ; Belongs to the LTI78/LTI65 family. (710 aa)
RD22BURP domain protein RD22; Acts to suppress chlorophyll degradation under moisture stress. (392 aa)
HSFA6AHeat stress transcription factor A-6a; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). (282 aa)
APX2L-ascorbate peroxidase 2, cytosolic; Plays a key role in hydrogen peroxide removal. (251 aa)
IPS2Inositol-3-phosphate synthase isozyme 2; Involved in myo-inositol synthesis. (510 aa)
RFS1Probable galactinol--sucrose galactosyltransferase 1; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (754 aa)
RFS6Probable galactinol--sucrose galactosyltransferase 6; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (749 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
ZAT10Zinc finger protein ZAT10; Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. (227 aa)
HSFB1Heat stress transcription factor B-1; Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE); Belongs to the HSF family. Class B subfamily. (284 aa)
RFS5Probable galactinol--sucrose galactosyltransferase 5; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity); Belongs to the glycosyl hydrolases 36 family. (783 aa)
GOLS2Galactinol synthase 2; Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants. Promotes stress tolerance of factors such as drought, chilling, salinity and methylviologen (MV), a superoxide radical generating drug, by mediating an increase in levels of the endogenous osmoprotective compounds, galactinol and raffinose; Belongs to the glycosyltransferase 8 family. Galactosyltransferase subfamily. (335 aa)
EGY3Probable zinc metallopeptidase EGY3, chloroplastic; Probable membrane-associated metalloprotease that may be involved in chloroplast development; Belongs to the peptidase M50B family. (573 aa)
HSFA1DHeat stress transcription factor A-1d; Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). (485 aa)
HSFA6bHeat stress transcription factor A-6b; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). (406 aa)
HSFA9Heat stress transcription factor A-9; Seed-specific transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Seems to be specialized for the developmental expression of heat shock protein (HSP) genes during seed maturation. Activated by ABI3; Belongs to the HSF family. Class A subfamily. (331 aa)
PKLCHD3-type chromatin-remodeling factor PICKLE; Chromatin remodeling factor that represses the expression of embryonic trait genes (such as NFYB9/LEC1) upon and after seed germination and thus enables the developmental switch to post- germinative growth. Silences some MADS-box proteins such as PHE1 and PHE2. Plays a role during carpel differentiation. Regulates late processes in cytokinin signaling. (1384 aa)
HSP70-5Heat shock 70 kDa protein 5; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (646 aa)
WRKY1WRKY transcription factor 1; Transcription factor. Binds to a 5'-CGTTGACCGAG-3' consensus core sequence which contains a W box, a frequently occurring elicitor- responsive cis-acting element; Belongs to the WRKY group I family. (487 aa)
HSP26.526.5 kDa heat shock protein, mitochondrial. (232 aa)
RFS4Probable galactinol--sucrose galactosyltransferase 4; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (876 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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