Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APX3 | CBL4 | Q42564 | O81223 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Calcineurin B-like protein 4; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the end [...] | 0.545 |
| APX3 | CIPK24 | Q42564 | Q9LDI3 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | CBL-interacting serine/threonine-protein kinase 24; Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Phosphorylates CBL1, CBL4 and CBL10. | 0.654 |
| APX3 | DHAR1 | Q42564 | Q9FWR4 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Glutathione S-transferase DHAR1, mitochondrial; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses, subsequently to biotic or abiotic inducers. As a peripheral membrane protein, could also function as voltage-gated ion channel. Belongs to the GST superfamily. DHAR family. | 0.978 |
| APX3 | DHAR2 | Q42564 | Q9FRL8 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Glutathione S-transferase DHAR2; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses. Plays a role in ozone tolerance; Belongs to the GST superfamily. DHAR family. | 0.979 |
| APX3 | EMB2360 | Q42564 | P42770 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Glutathione reductase, chloroplastic; Maintains high levels of reduced glutathione in the chloroplast. | 0.951 |
| APX3 | GPX1 | Q42564 | P52032 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | 0.931 |
| APX3 | GPX2 | Q42564 | O04922 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable glutathione peroxidase 2; May constitute a glutathione peroxidase-like protective system against oxidative stresses; Belongs to the glutathione peroxidase family. | 0.931 |
| APX3 | GPX3 | Q42564 | O22850 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable glutathione peroxidase 3, mitochondrial; May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e.g. the phosphatase activity of ABI1 and ABI2) when oxidized by H(2)O(2), probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H(2)O(2). Confers tolerance to drought stress, by [...] | 0.929 |
| APX3 | GPX4 | Q42564 | Q8L910 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable glutathione peroxidase 4; May constitute a glutathione peroxidase-like protective system against oxidative stresses; Belongs to the glutathione peroxidase family. | 0.931 |
| APX3 | GPX5 | Q42564 | Q9LYB4 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable glutathione peroxidase 5; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.932 |
| APX3 | GPX6 | Q42564 | O48646 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | 0.933 |
| APX3 | GPX7 | Q42564 | Q9SZ54 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Putative glutathione peroxidase 7, chloroplastic; May constitute a glutathione peroxidase-like protective system against oxidative stresses. | 0.929 |
| APX3 | GPX8 | Q42564 | Q8LBU2 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Probable glutathione peroxidase 8; May constitute a glutathione peroxidase-like protective system against oxidative stresses; Belongs to the glutathione peroxidase family. | 0.929 |
| APX3 | NHX7 | Q42564 | Q9LKW9 | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | Sodium/hydrogen exchanger 7; Acts in electroneutral exchange of protons for cations such as Na(+) or Li(+) across plasma membrane. Involved in Na(+) and K(+) homeostasis. Required for cytoplasmic Na(+) and Li(+) detoxification by secreting them from the cytoplasm to the extracellular space. Regulates Na(+) content of the xylem sap. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.722 |
| CBL4 | APX3 | O81223 | Q42564 | Calcineurin B-like protein 4; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the end [...] | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | 0.545 |
| CBL4 | CIPK24 | O81223 | Q9LDI3 | Calcineurin B-like protein 4; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the end [...] | CBL-interacting serine/threonine-protein kinase 24; Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Phosphorylates CBL1, CBL4 and CBL10. | 0.999 |
| CBL4 | GPX3 | O81223 | O22850 | Calcineurin B-like protein 4; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the end [...] | Probable glutathione peroxidase 3, mitochondrial; May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e.g. the phosphatase activity of ABI1 and ABI2) when oxidized by H(2)O(2), probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H(2)O(2). Confers tolerance to drought stress, by [...] | 0.429 |
| CBL4 | NHX7 | O81223 | Q9LKW9 | Calcineurin B-like protein 4; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the end [...] | Sodium/hydrogen exchanger 7; Acts in electroneutral exchange of protons for cations such as Na(+) or Li(+) across plasma membrane. Involved in Na(+) and K(+) homeostasis. Required for cytoplasmic Na(+) and Li(+) detoxification by secreting them from the cytoplasm to the extracellular space. Regulates Na(+) content of the xylem sap. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.979 |
| CBL8 | CIPK24 | Q9FUQ7 | Q9LDI3 | Calcineurin B-like protein 8; Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner; Belongs to the calcineurin regulatory subunit family. | CBL-interacting serine/threonine-protein kinase 24; Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Phosphorylates CBL1, CBL4 and CBL10. | 0.645 |
| CIPK24 | APX3 | Q9LDI3 | Q42564 | CBL-interacting serine/threonine-protein kinase 24; Involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Activates the vacuolar H(+)/Ca(2+) antiporter CAX1 and operates in synergy with CBL4/SOS3 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Phosphorylates CBL1, CBL4 and CBL10. | L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. | 0.654 |
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