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BRM BRM cox2 cox2 ccmB ccmB rps7 rps7 nad9 nad9 nad6 nad6 mttB mttB nad3 nad3 ccmC ccmC rps12 rps12 nad7 nad7 matR matR nad4L nad4L ABCI5 ABCI5 rpl16 rpl16 rps14 rps14 ATP9 ATP9 ND6 ND6 COX1 COX1 rps7-A rps7-A rps12-A rps12-A CCMC CCMC RPS12 RPS12 ND3 ND3 RPS7 RPS7 CCMB CCMB COX2 COX2 NAD7 NAD7 ND4L ND4L atp9 atp9 RPS1 RPS1 SDH4 SDH4 RPL16 RPL16 NAD9 NAD9 RPL10 RPL10 rps14-2 rps14-2 DDM1 DDM1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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BRMATP-dependent helicase BRM; ATPase subunit of a multiprotein complex equivalent of the SWI/SNF complex that acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. Represses embryonic genes in leaves and controls shoot development and flowering. Activates flower homeotic genes. The association of BRM with its target genes requires REF6. Necessary to acquire heat stress (HS) memory, by globally binding to HS memory genes. (2193 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
ccmBCytochrome c biogenesis B. (206 aa)
rps7Ribosomal protein S7. (148 aa)
nad9NADH dehydrogenase subunit 9; Belongs to the complex I 30 kDa subunit family. (190 aa)
nad6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (205 aa)
mttBTransport membrane protein. (280 aa)
nad3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
ccmCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
rps12Ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (125 aa)
nad7NADH dehydrogenase subunit 7; Belongs to the complex I 49 kDa subunit family. (394 aa)
matRMaturase. (656 aa)
nad4LNADH dehydrogenase subunit 4L. (100 aa)
ABCI5Putative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
rpl1650S ribosomal protein L16, chloroplastic; Belongs to the universal ribosomal protein uL16 family. (135 aa)
rps1430S ribosomal protein S14, chloroplastic; Binds 16S rRNA, required for the assembly of 30S particles. Belongs to the universal ribosomal protein uS14 family. (100 aa)
ATP9ATP synthase subunit 9, mitochondrial; This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase. (85 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (205 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (527 aa)
rps7-A30S ribosomal protein S7, chloroplastic; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. (155 aa)
rps12-A30S ribosomal protein S12, chloroplastic; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity). (123 aa)
CCMCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (232 aa)
RPS12Ribosomal protein S12, mitochondrial; Protein S12 is involved in the translation initiation step; Belongs to the universal ribosomal protein uS12 family. (125 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (119 aa)
RPS7Ribosomal protein S7, mitochondrial; One of the primary rRNA binding proteins, it binds directly to 18S rRNA where it nucleates assembly of the head domain of the small subunit; Belongs to the universal ribosomal protein uS7 family. (148 aa)
CCMBPutative cytochrome c biogenesis ccmB-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. (206 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
NAD7NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. (394 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (100 aa)
atp9ATP synthase subunit 9, mitochondrial; Belongs to the ATPase C chain family. (85 aa)
RPS130S ribosomal protein S1, chloroplastic; Required for optimal plastid performance in terms of photosynthesis and growth. Required for the translation of plastid mRNAs. Involved in cellular heat stress response and required for heat tolerance. Required for transcriptional activation of HSFA2 and its target genes in response to heat stress. Plays a critical role in biosynthesis of thylakoid membrane proteins encoded by chloroplast genes. (416 aa)
SDH4Succinate dehydrogenase subunit 4, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (151 aa)
RPL1660S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. (179 aa)
NAD9NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (190 aa)
RPL1050S ribosomal protein L10, chloroplastic; This protein binds directly to 23S ribosomal RNA. (220 aa)
rps14-2Mitochondrial ribosomal protein S14. (164 aa)
DDM1ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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