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HDA9 HDA9 ABF1 ABF1 A3G2XYLT A3G2XYLT DPBF3 DPBF3 EHD1 EHD1 TGA9 TGA9 GRXC7 GRXC7 EHD2 EHD2 BZIP8 BZIP8 FD FD TFL1 TFL1 DFRA DFRA HY5 HY5 BZIP18 BZIP18 BZIP34 BZIP34 TGA10 TGA10 GRXC8 GRXC8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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HDA9Histone deacetylase 9; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. (426 aa)
ABF1ABSCISIC ACID-INSENSITIVE 5-like protein 4; Binds to the ABA-responsive element (ABRE). Could participate in abscisic acid-regulated gene expression; Belongs to the bZIP family. ABI5 subfamily. (392 aa)
A3G2XYLTAnthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase; Contributes to the last few anthocyanin biosynthetic steps. Converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1->2)glucoside. Can use 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose as substrates. (468 aa)
DPBF3ABSCISIC ACID-INSENSITIVE 5-like protein 2; Binds to the embryo specification element and the ABA- responsive element (ABRE) of the Dc3 gene promoter. Could participate in abscisic acid-regulated gene expression during seed development. (297 aa)
EHD1EH domain-containing protein 1; Involved in endocytosis positive regulation. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Confers salt tolerance. (545 aa)
TGA9Transcription factor TGA9; Together with TGA10, basic leucine-zipper transcription factor required for anther development, probably via the activation of SPL expression in anthers and via the regulation of genes with functions in early and middle tapetal development. Required for signaling responses to pathogen-associated molecular patterns (PAMPs) such as flg22 that involves chloroplastic reactive oxygen species (ROS) production and subsequent expression of H(2)O(2)- responsive genes. (481 aa)
GRXC7Glutaredoxin-C7; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development as a regulator of petal primorida initiation and further petal morphogenesis. May mediate post-translational modifications of target proteins required for normal petal organ initiation and morphogenesis. ROXY1/TGA protein interactions can occur in vivo and support their biological relevance in petal development. May be involved in the regulation of the floral regulato [...] (136 aa)
EHD2EH domain-containing protein 2; Involved in endocytosis negative regulation, probably by influencing actin organization. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Exhibits an inhibitory effect on endocytosis when over-expressed. (546 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
FDProtein FD; Transcription factor required for the transition to flowering promoted by FT; Belongs to the bZIP family. (285 aa)
TFL1Protein TERMINAL FLOWER 1; Controls inflorescence meristem identity and is required for maintenance of an indeterminate inflorescence. Prevents the expression of 'APETALA1' and 'LEAFY'. Also plays a role in the regulation of the time of flowering in the long-day flowering pathway. May form complexes with phosphorylated ligands by interfering with kinases and their effectors (By similarity). (177 aa)
DFRADihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (382 aa)
HY5Transcription factor HY5; Transcription factor that promotes photomorphogenesis in light. Acts downstream of the light receptor network and directly affects transcription of light-induced genes. Specifically involved in the blue light specific pathway, suggesting that it participates in transmission of cryptochromes (CRY1 and CRY2) signals to downstream responses. In darkness, its degradation prevents the activation of light-induced genes (Probable). Acts coordinately with SPL7 to regulate the microRNA miR408 and its target genes in response to changes in light and copper conditions. R [...] (168 aa)
BZIP18bZIP transcription factor 18; Transcription factor that may participate with bZIP34 in the gametophytic control of pollen development. (367 aa)
BZIP34Basic leucine zipper 34; Transcriptional activator involved in the sporophytic control of cell wall patterning and gametophytic control of pollen development. May play a role in the control of metabolic pathways regulating cellular transport and lipid metabolism. (321 aa)
TGA10Transcription factor TGA10; Together with TGA9, basic leucine-zipper transcription factor required for anther development, probably via the activation of SPL expression in anthers and via the regulation of genes with functions in early and middle tapetal development. Required for signaling responses to pathogen-associated molecular patterns (PAMPs) such as flg22 that involves chloroplastic reactive oxygen species (ROS) production and subsequent expression of H(2)O(2)-responsive genes ; Belongs to the bZIP family. (460 aa)
GRXC8Glutaredoxin-C8; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). Involved in flower development; Belongs to the glutaredoxin family. CC-type subfamily. (140 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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