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F6N18.16 F6N18.16 ECI1 ECI1 LACS1 LACS1 ECI2 ECI2 ECI3 ECI3 ACX2 ACX2 ACX1 ACX1 ADH1 ADH1 ACX3 ACX3 F3E22.17 F3E22.17 CYP86A1 CYP86A1 F1N20.210 F1N20.210 PED1 PED1 KAT5 KAT5 ECHIA ECHIA ALDH3H1 ALDH3H1 ALDH3F1 ALDH3F1 T4C12_30 T4C12_30 KAT1-2 KAT1-2 LACS7 LACS7 LACS6 LACS6 IBR3 IBR3 AAT1 AAT1 ALDH2B7 ALDH2B7 F13O11.3 F13O11.3 ALDH3I1 ALDH3I1 AAE15 AAE15 ACX4 ACX4 ADH2 ADH2 CYP704B1 CYP704B1 LACS3 LACS3 LACS9 LACS9 K5J14.5 K5J14.5 AACT1 AACT1 AAE16 AAE16 ACX3.2 ACX3.2 LACS8 LACS8 F12K8.22 F12K8.22 F12K8.21 F12K8.21 ALDH2B4 ALDH2B4 ALDH7B4 ALDH7B4 LACS5 LACS5 LACS4 LACS4 LACS2 LACS2 MFP2 MFP2 AIM1 AIM1 ACX1.2 ACX1.2
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second shell of interactors
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proteins of unknown 3D structure
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F6N18.16Alcohol dehydrogenase-like 3. (394 aa)
ECI1Enoyl-CoA delta isomerase 1, peroxisomal; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids. (240 aa)
LACS1Long chain acyl-CoA synthetase 1; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Acts in both the wax and cutin pathways. Preferentially uses palmitate, palmitoleate, linoleate and eicosenoate. Seems to have a specific activity against very long-chain fatty acid (VLCFA) class with acids longer than 24 carbons (C(24)). (660 aa)
ECI2Enoyl-CoA delta isomerase 2, peroxisomal; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids. Involved with IBR1 and IBR3 in the peroxisomal beta-oxidation of indole-3- butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin. (240 aa)
ECI3Enoyl-CoA delta isomerase 3; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Essential for the beta oxidation of unsaturated fatty acids. (238 aa)
ACX2Acyl-coenzyme A oxidase 2, peroxisomal; Catalyzes the desaturation of long-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on substrates longer than C14 and mostly with C18-CoA. Activity on long-chain mono-unsaturated substrates is double than with the corresponding saturated substrates. (692 aa)
ACX1Peroxisomal acyl-coenzyme A oxidase 1; Catalyzes the desaturation of both long- and medium-chain acyl-CoAs to 2-trans-enoyl-CoAs. Most active with C14-CoA. Activity on long-chain mono-unsaturated substrates is 40% higher than with the corresponding saturated substrates. Seems to be an important factor in the general metabolism of root tips. May be involved in the biosynthesis of jasmonic acid. (664 aa)
ADH1Alcohol dehydrogenase class-P; Alcohol dehydrogenase mostly active on ethanol (EtOH), but exhibits broad substrates selectivity for primary and secondary alcohols (e.g. butanol, propyl alcohol, pentanol, isopentanol, ethylene glycol, isopropanol, methanol and tertiary butyl alcohol). Converts allyl alcohol to highly toxic acryl- aldehyde. Required for survival and acclimation in hypoxic conditions, especially in roots. (379 aa)
ACX3Acyl-coenzyme A oxidase 3, peroxisomal; Catalyzes the desaturation of medium-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on C8:0- to C14:0-CoA with a maximal activity on C12:0-CoA. (675 aa)
F3E22.17Putative acyl-coenzyme A oxidase At3g06690. (187 aa)
CYP86A1Cytochrome P450 86A1; Catalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18 but not on hexadecane; Belongs to the cytochrome P450 family. (513 aa)
F1N20.210Alcohol dehydrogenase-like 5. (389 aa)
PED13-ketoacyl-CoA thiolase 2, peroxisomal; Involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Confers sensitivity to 2,4-dichlorophenoxybutiric acid (2,4-DB). Required for local and systemic induction of jasmonic acid (JA) biosynthesis after wounding. Seems to be involved in JA biosynthesis during senescence. (462 aa)
KAT53-ketoacyl-CoA thiolase 5, peroxisomal; Probably involved in long chain fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Involved in systemic jasmonic acid (JA) biosynthesis after wounding and may be during senescence. (457 aa)
ECHIAProbable enoyl-CoA hydratase 1, peroxisomal; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. (265 aa)
ALDH3H1Aldehyde dehydrogenase family 3 member H1; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Is strictely NAD(+) specific. (484 aa)
ALDH3F1Aldehyde dehydrogenase family 3 member F1; Belongs to the aldehyde dehydrogenase family. (484 aa)
T4C12_30Alcohol dehydrogenase-like 6. (381 aa)
KAT1-23-ketoacyl-CoA thiolase 1, peroxisomal; Involved in fatty-acid beta-oxidation prior to gluconeogenesis during germination and subsequent seedling growth. Implicated in jasmonic acid (JA) biosynthesis (By similarity). Belongs to the thiolase-like superfamily. Thiolase family. (443 aa)
LACS7Long chain acyl-CoA synthetase 7, peroxisomal; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate. Displays redundant function with LACS7 into the seed development process (By similarity). (700 aa)
LACS6Long chain acyl-CoA synthetase 6, peroxisomal; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate. Might play a regulatory role both in fatty acid import into glyoxysomes and in fatty acid beta-oxidation. Displays redundant function with LACS7 into the seed development process. (701 aa)
IBR3Probable acyl-CoA dehydrogenase IBR3; Involved with IBR1 and IBR10 in the peroxisomal beta- oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin. May be responsible for catalyzing the first step in IBA-CoA beta-oxidation. May play a role in defense response to pathogenic bacteria. (824 aa)
AAT1Acetyl-CoA acetyltransferase, cytosolic 1. (403 aa)
ALDH2B7Aldehyde dehydrogenase family 2 member B7, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family. (534 aa)
F13O11.3Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
ALDH3I1Aldehyde dehydrogenase family 3 member I1, chloroplastic; Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long- chain saturated aldehydes are preferred substrates, while the short- chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent. (550 aa)
AAE15Long-chain-fatty-acid--[acyl-carrier-protein] ligase AEE15, chloroplastic; Probably involved in the activation of fatty acids to acyl- carrier-protein prior to fatty acid elongation in plastids. Acts on medium- to long-chain fatty acids. (727 aa)
ACX4Acyl-coenzyme A oxidase 4, peroxisomal; Catalyzes the desaturation of short-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester). (436 aa)
ADH2Alcohol dehydrogenase class-3; Plays a central role in formaldehyde detoxification. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (379 aa)
CYP704B1Cytochrome P450 704B1; Involved in pollen wall development. Catalyzes the conversion of long-chain fatty acids to the corresponding omega-hydroxylated fatty acids. Omega-hydroxylated fatty acids, together with in-chain hydroxylated fatty acids, are key monomeric aliphatic building blocks for sporopollenin synthesis during exine formation. Belongs to the cytochrome P450 family. (524 aa)
LACS3Long chain acyl-CoA synthetase 3; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
LACS9Long chain acyl-CoA synthetase 9, chloroplastic; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate. (691 aa)
K5J14.5Alcohol dehydrogenase-like 7. (390 aa)
AACT1Probable acetyl-CoA acetyltransferase, cytosolic 2; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
AAE16Probable acyl-activating enzyme 16, chloroplastic; May be involved in the activation of fatty acids to acyl- carrier-protein; Belongs to the ATP-dependent AMP-binding enzyme family. (722 aa)
ACX3.2Putative acyl-coenzyme A oxidase 3.2, peroxisomal; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (675 aa)
LACS8Long chain acyl-CoA synthetase 8; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (720 aa)
F12K8.22Alcohol dehydrogenase-like 1. (388 aa)
F12K8.21Alcohol dehydrogenase-like 2. (386 aa)
ALDH2B4Aldehyde dehydrogenase family 2 member B4, mitochondrial; Possesses activity on acetaldehyde and glycolaldehyde in vitro; Belongs to the aldehyde dehydrogenase family. (538 aa)
ALDH7B4Aldehyde dehydrogenase family 7 member B4. (508 aa)
LACS5Long chain acyl-CoA synthetase 5; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (666 aa)
LACS4Long chain acyl-CoA synthetase 4; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (666 aa)
LACS2Long chain acyl-CoA synthetase 2; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Acts in the cutin pathway. Preferentially uses palmitate, palmitoleate, oleate and linoleate. Required for repression of lateral root formation through its role in cutin biosynthesis and subsequent aerial tissues permeability. Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
MFP2Enoyl-CoA hydratase/3-2-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18). Possesses 3-hydroxy-3- phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA [...] (725 aa)
AIM1Enoyl-CoA hydratase/3-2-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in peroxisomal fatty acid beta-oxidation. Required for wound-induced jasmonate biosynthesis. Possesses enoyl-CoA hydratase activity against short chain substrates (C4-C6) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C16). Possesses cinnamoyl-CoA hydratase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of benzoylated glucosinolates (BGs) and substituted hydroxy [...] (721 aa)
ACX1.2Putative peroxisomal acyl-coenzyme A oxidase 1.2; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (664 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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