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PSD3 PSD3 PSS1 PSS1 LPLAT1 LPLAT1 F4J010_ARATH F4J010_ARATH CCT2 CCT2 DGK6 DGK6 DGK7 DGK7 PSD2 PSD2 CDS1 CDS1 GPDHC1 GPDHC1 PLDBETA2 PLDBETA2 CDS2 CDS2 GPAT6 GPAT6 PGPS1 PGPS1 NPC2 NPC2 EMB1187 EMB1187 AAPT1 AAPT1 AAPT2 AAPT2 PLDALPHA3 PLDALPHA3 PLDBETA1 PLDBETA1 LPP4 LPP4 DGK4 DGK4 CDS3 CDS3 PLDALPHA1 PLDALPHA1 DGK1 DGK1 ATS1 ATS1 GPAT8 GPAT8 GDPD3 GDPD3 LCAT4 LCAT4 PSD1 PSD1 PIS2 PIS2 GPAT9 GPAT9 LPAT1 LPAT1 NPC6 NPC6 LPAT4 LPAT4 F1O17.1 F1O17.1 LPEAT1 LPEAT1 NPC1 NPC1 F28I16.210 F28I16.210 PIS1 PIS1 LPP3 LPP3 LPAT2 LPAT2 PLA2-ALPHA PLA2-ALPHA LPEAT2 LPEAT2 DGK3 DGK3 LCAT3 LCAT3 CLS CLS NMT2 NMT2 DAD1-2 DAD1-2 GLY1 GLY1 CDS4 CDS4 F22F7.4 F22F7.4 DGK5 DGK5 PLDDELTA PLDDELTA NMT3 NMT3 PLDALPHA4 PLDALPHA4 GDPD5 GDPD5 LPLAT2 LPLAT2 GPAT5 GPAT5 DGK2 DGK2 GDPD2 GDPD2 PAH2 PAH2 NMT1 NMT1 GPAT2 GPAT2 LPAT5 LPAT5 GPAT7 GPAT7 GPAT4 GPAT4 PLDZETA1 PLDZETA1 T20N10_180 T20N10_180 SDP1 SDP1 CDS5 CDS5 SDP1L SDP1L PGPS2 PGPS2 CK1 CK1 PLPZETA2 PLPZETA2 F17A17.3 F17A17.3 NPC5 NPC5 PLMT PLMT F22K18.70 F22K18.70 DHAPRD DHAPRD GDPD6 GDPD6 PAH1 PAH1 GDPD1 GDPD1 GPAT1 GPAT1 NPC4 NPC4 SDP6 SDP6 PLDALPHA2 PLDALPHA2 LPAT3 LPAT3 GPAT3 GPAT3 F17A8.110 F17A8.110 PLDGAMMA2 PLDGAMMA2 PLDGAMMA3 PLDGAMMA3 PLDGAMMA1 PLDGAMMA1 LPP2 LPP2 LPP1 LPP1 CCT1-2 CCT1-2 At1g78690p At1g78690p PECT1 PECT1
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PSD3Phosphatidylserine decarboxylase 3 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Contributes only to a minor proportion of PtdEtn production. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (635 aa)
PSS1CDP-diacylglycerol--serine O-phosphatidyltransferase 1; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Is essential for phosphatidylserine (PS) biosynthesis and PE seems to be the most plausible substrate. Plays an important role in microspore maturation; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (425 aa)
LPLAT1Lysophospholipid acyltransferase 1; Lysophospholipid acyltransferase with broad specificity. Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn- glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn- glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl- sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphati [...] (462 aa)
F4J010_ARATHAlpha/beta-Hydrolases superfamily protein. (274 aa)
CCT2Choline-phosphate cytidylyltransferase 2; Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine. Catalyzes the formation of CDP- choline; Belongs to the cytidylyltransferase family. (304 aa)
DGK6Diacylglycerol kinase 6; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress. (466 aa)
DGK7Diacylglycerol kinase 7; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress xhibits high specificity for 1,2-dioleoyl-sn-glycerol (1,2- DOG), 1-palmitoyl, 2-oleoyl-sn-glycerol (1,2 POG), 1-stearoyl, 2- linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG). (492 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Contributes only to a minor proportion of PtdEtn production. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (635 aa)
CDS1Phosphatidate cytidylyltransferase 1; May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction. (421 aa)
GPDHC1Glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic; Involved in cell redox homeostasis. Required for maintaining a steady state cellular NADH/NAD(+) ratio through a mitochondrial glycerol-3-phosphate redox shuttle. May function with the mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase SDP6 to shuttle reducing equivalents into the mitochondria for respiration. (462 aa)
PLDBETA2Phospholipase D beta 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine or N- acylphosphatidylethanolamine as substrates; Belongs to the phospholipase D family. C2-PLD subfamily. (927 aa)
CDS2Phosphatidate cytidylyltransferase 2; May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction. (423 aa)
GPAT6Glycerol-3-phosphate 2-O-acyltransferase 6; Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate, a step in cutin biosynthesis. Belongs to the GPAT/DAPAT family. (501 aa)
PGPS1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1, chloroplastic; Catalyzes the committed step to the synthesis of the acidic phospholipids. Transfers specifically a phosphatidyl group from CDP- diacylglycerol to glycerol-3-phosphate to form phosphatidylglycerophosphate. Cannot catalyze the phosphatidyl group transfer to inositol, serine, choline or phosphatidylglycerol. Possesses high activity with CDP-dipalmitoylglycerol and low activity with CDP-dioleoylglycerol. (296 aa)
NPC2Non-specific phospholipase C2. (514 aa)
EMB1187Probable ethanolamine kinase; Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis (By similarity). (374 aa)
AAPT1Choline/ethanolaminephosphotransferase 1; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (389 aa)
AAPT2Choline/ethanolaminephosphotransferase 2; Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (389 aa)
PLDALPHA3Phospholipase D alpha 3; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Active with phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and phosphatidylserine (PS) as substrates. No activity toward phosphatidylinositol (PI) or PIP2. Positively mediates plant responses to hyperosmotic stresses and promotes root growth, flowering, and stress avoidance. Not involved in the abscisic acid regulation of stomatal movement and transpirational water loss. Belongs to the phospholipase D family. C2-PLD s [...] (820 aa)
PLDBETA1Phospholipase D beta 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Involved in regulating stomatal movement and plant-water status. Can use phosphatidylserine (PS) and phosphatidylethanolamine (PE) as substrates only in the presence of PIP2. Can use phosphatidylcholine (PC), phosphatidylglycerol (PG) [...] (1083 aa)
LPP4Probable lipid phosphate phosphatase 4. (308 aa)
DGK4Diacylglycerol kinase 4; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity). (487 aa)
CDS3Phosphatidate cytidylyltransferase 3; May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction. (471 aa)
PLDALPHA1Phospholipase D alpha 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action and response to stress, characterized by acidification of the cell. Involved in wound induction of jasmonic acid. May be involved in membrane lipid remodeling. Probably involved in freezing tolerance by modulating the cold-responsive genes and accumulation of osmolytes. Can use phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) as subst [...] (810 aa)
DGK1Diacylglycerol kinase 1; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity). (728 aa)
ATS1Glycerol-3-phosphate acyltransferase, chloroplastic; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate. The enzyme from chilling-resistant plants discriminates against non-fluid palmitic acid and selects oleic acid whereas the enzyme from sensitive plants accepts both fatty acids. This is an oleate-selective acyltransferase. (459 aa)
GPAT8Probable glycerol-3-phosphate acyltransferase 8; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. (500 aa)
GDPD3Glycerophosphodiester phosphodiesterase GDPD3. (370 aa)
LCAT4Lecithin-cholesterol acyltransferase-like 4; Belongs to the AB hydrolase superfamily. Lipase family. (535 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Contributes only to a minor proportion of PtdEtn production. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (453 aa)
PIS2Probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). (225 aa)
GPAT9Glycerol-3-phosphate acyltransferase 9; Essential protein. Required for male and female gametophytes development. Exhibits sn-1 acyltransferase activity with high specificity for acyl-coenzyme A, thus triggering storage lipid biosynthesis and playing an important role in the Kennedy pathway of glycerolipid biosynthesis. Catalyzes triacylglycerol (TAG) accumulation involved in membrane lipid and oil biosynthesis, especially in seeds. Contributes also to the biosynthesis of both polar lipids and TAG in developing leaves, as well as lipid droplet production in developing pollen grains. Se [...] (376 aa)
LPAT11-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic; Plastidial enzyme of the prokaryotic glycerol-3-phosphate pathway that converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at position sn-2. Utilizes palmitoyl-ACP (16:0-ACP) to produce phosphatidic acid containing a saturated group at position sn-2, which is characteristic of lipids synthesized by the prokaryotic pathway. In vitro, can use 16:0-CoA as acyl donor. Essential for embryo development during the transition from the globular to the heart stage when chloroplasts begin [...] (356 aa)
NPC6Non-specific phospholipase C6. (520 aa)
LPAT4Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4; May convert lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). Has no activity when expressed in bacteria or yeast; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (378 aa)
F1O17.1Probable choline kinase 2; Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity). Belongs to the choline/ethanolamine kinase family. (350 aa)
LPEAT1Lysophospholipid acyltransferase LPEAT1; Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates. Exhibits strong acylation activity of lysophosphatidylethanolamine (LPE) and lysophosphatidate (LPA), with lower activity on lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS). Has a preference for 18:1-LPE over 16:0-LPE as acceptor and palmitoyl-CoA (16:0-CoA) as acyl donor. Activity is calcium-independent; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (398 aa)
NPC1Non-specific phospholipase C1. (533 aa)
F28I16.210Alpha/beta-Hydrolases superfamily protein. (252 aa)
PIS1CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (227 aa)
LPP3Putative lipid phosphate phosphatase 3, chloroplastic; Belongs to the PA-phosphatase related phosphoesterase family. (364 aa)
LPAT21-acyl-sn-glycerol-3-phosphate acyltransferase 2; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Has preference for C- 18-CoA substrates compared to C-16-CoA substrates. Required for female but not male gametophyte development. (389 aa)
PLA2-ALPHAPhospholipase A2-alpha; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli. Modulates the trafficking of PIN proteins to the plasma membrane. Negatively regulates MYB30 transcriptional activity and hypersensitive response control. (148 aa)
LPEAT2Lysophospholipid acyltransferase LPEAT2; Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates. Exhibits strong acylation activity of lysophosphatidylethanolamine (LPE) and lower activity on lysophosphatidate (LPA). Has a preference for 18:1- LPE over 16:0-LPE as acceptor and palmitoyl-CoA (16:0-CoA) as acyl donor. Activity is calcium-independent. (539 aa)
DGK3Diacylglycerol kinase 3; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity). (488 aa)
LCAT3Phospholipase A(1) LCAT3; Hydrolyzes the sn-1 acylester bond of phospholipids. Phosphatidylcholine, phosphatidylethanolamine and phosphatidic acid can be used as substrates. Weak activity with lysophosphatidylcholine and no activity with tripalmitoylglycerol and cholesteryl oleate. Seems to have a preference for unsaturated fatty acids at the sn-1 position. (447 aa)
CLSCardiolipin synthase (CMP-forming), mitochondrial; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). Cannot catalyze the phosphatidyl group transfer from one PG molecule to another to form CL. Possesses high activity with PG species carrying dioleoyl groups and low activity with species carrying one or two palmitoyl groups. CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochond [...] (341 aa)
NMT2Phosphomethylethanolamine N-methyltransferase; Catalyzes N-methylation of phosphomonomethylethanolamine and phosphodimethylethanolamine, the two methylation steps required to convert phosphomonoethanolamine to phosphocholine. Unlike NMT1, NMT2 cannot utilize phosphoethanolamine as substrate in vitro. Belongs to the class I-like SAM-binding methyltransferase superfamily. PEAMT family. (491 aa)
DAD1-2Phospholipase A(1) DAD1, chloroplastic; Sn-1-specific phospholipase that releases free fatty acids from phospholipids. Low activity on galactolipids and triacylglycerols. Catalyzes the initial step of jasmonic acid biosynthesis. Not essential for jasmonate biosynthesis after wounding or upon pathogen infection. Belongs to the AB hydrolase superfamily. Lipase family. (447 aa)
GLY1Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, chloroplastic; Required to supply glycerol-3-phosphate in the chloroplast for the synthesis of glycerolipids. Required for activation of systemic acquired resistance (SAR). Provision of glycerol-3-phosphate may be involved in generating lipid signals necessary for mediating defense responses and SAR. Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (420 aa)
CDS4Phosphatidate cytidylyltransferase 4, chloroplastic; May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction. Promotes the biosynthesis of plastidial phosphatidylglycerol (PG) which is required for structure and function of thylakoid membranes and, hence, for photoautotrophic growth; Belongs to the CDS family. (391 aa)
F22F7.4Tafazzin family protein; Belongs to the taffazin family. (448 aa)
DGK5Diacylglycerol kinase 5; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity); Belongs to the eukaryotic diacylglycerol kinase family. (509 aa)
PLDDELTAPhospholipase D delta; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). May be involved in PA accumulation in the dehydration stress response and in the transduction of hormonal and environmental signals to the microtubules cytoskeleton. Prefers phosphatidylethanolamine to phosphatidylcholine as substrate. Involved in H(2)O(2) and abscisic acid (ABA)-induced stomatal closure. Involved in nitric oxide (NO) signaling during stomatal closure. Plays a positive role in ABA-promoted senescence. Involved in basal defense and nonhost [...] (868 aa)
NMT3Phosphoethanolamine N-methyltransferase 3; Catalyzes N-methylation of phosphoethanolamine, phosphomonomethylethanolamine and phosphodimethylethanolamine, the three methylation steps required to convert phosphoethanolamine to phosphocholine. (490 aa)
PLDALPHA4Phospholipase D alpha 4; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Promotes growth and plays a role in nitrogen signaling. (762 aa)
GDPD5Glycerophosphodiester phosphodiesterase GDPD5; Belongs to the glycerophosphoryl diester phosphodiesterase family. (392 aa)
LPLAT2Lysophospholipid acyltransferase 2; Lysophospholipid acyltransferase with broad specificity. Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn- glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn- glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl- sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphati [...] (465 aa)
GPAT5Glycerol-3-phosphate acyltransferase 5; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. (502 aa)
DGK2Diacylglycerol kinase 2; Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress. Exhibits high specificity for 1-stearoyl-2- arachidonoyl- sn-glycerol (1,2-SAG), 1,2-dioleoyl-sn-glycerol (1,2- DOG), 1-palmitoyl, 2-oleoyl-sn-glycerol (1,2 POG), 1-stearoyl, 2- linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG), but has almost no activit [...] (712 aa)
GDPD2Glycerophosphodiester phosphodiesterase GDPD2; Belongs to the glycerophosphoryl diester phosphodiesterase family. (374 aa)
PAH2Phosphatidate phosphatase PAH2; Magnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH1 to repress phospholipid biosynthesis at the endoplasmic reticulum (ER). May function indirectly as repressor of multiple enzymes involved in phospholipid biosynthesis. Is involved in the pathway of galactolipid synthesis in the ER, which is required for the membrane lipid remodeling, an essential adaptation mechanism to cope with phosphate starvation. (930 aa)
NMT1Phosphoethanolamine N-methyltransferase 1; Catalyzes N-methylation of phosphoethanolamine, phosphomonomethylethanolamine and phosphodimethylethanolamine, the three methylation steps required to convert phosphoethanolamine to phosphocholine. Required for root system development and epidermal cell integrity through its role in choline and phospholipid metabolism. (491 aa)
GPAT2Probable glycerol-3-phosphate acyltransferase 2; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Belongs to the GPAT/DAPAT family. (530 aa)
LPAT5Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5; May convert lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). Has no activity when expressed in bacteria or yeast. (375 aa)
GPAT7Glycerol-3-phosphate acyltransferase 7; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. (500 aa)
GPAT4Glycerol-3-phosphate 2-O-acyltransferase 4; Esterifies acyl-group from acyl-ACP to the sn-2 position of glycerol-3-phosphate, a step in cutin biosynthesis. Belongs to the GPAT/DAPAT family. (503 aa)
PLDZETA1Phospholipase D zeta 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective. Regulates root-hair morphogenesis. Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus-starved roots. Involved in root elongation during phosphate limitation. (1096 aa)
T20N10_180Haloacid dehalogenase (HAD) superfamily protein. (348 aa)
SDP1Triacylglycerol lipase SDP1; Involved in the release of fatty acids from the oil body in germinating seedlings. Could hydrolyze triacylglycerols and diacylglycerols but not monoacylglycerols, phospholipids, galactolipids or cholesterol esters. (825 aa)
CDS5Phosphatidate cytidylyltransferase 5, chloroplastic; May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction. Promotes the biosynthesis of plastidial phosphatidylglycerol (PG) which is required for structure and function of thylakoid membranes and, hence, for photoautotrophic growth; Belongs to the CDS family. (399 aa)
SDP1LTriacylglycerol lipase SDP1L; May be involved in the release of fatty acids from the oil body in germinating seedlings. Can hydrolyze triacylglycerols in vitro. (801 aa)
PGPS2CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (233 aa)
CK1Probable choline kinase 1; Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity). (346 aa)
PLPZETA2Phospholipase D zeta 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective. Regulates vesicle trafficking and auxin responses. Required for the normal cycling of PIN-2 containing vesicles. Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus- starved roots. Involved in root elongation during phosphate limitation. Belongs to the phospholipase D family. PXPH-PLD subfamily. (1046 aa)
F17A17.3Glycerol-3-phosphate dehydrogenase [NAD(+)] At3g07690, cytosolic; Required for glycerol-3-phosphate (G3P) accumulation during systemic acquired resistance (SAR) establishment. Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (456 aa)
NPC5Non-specific phospholipase C5; Non-specific phospholipase C (PLC) which assumes minor PLC activity during inorganic phosphate starvation. Can hydrolyze both phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Required for normal accumulation of digalactosyldiacylglycerol (DGDG) during phosphate limitation and may contribute to the conversion of phospholipids to diacylglycerol, the substrate for galactolipid synthesis. (521 aa)
PLMTPhosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (164 aa)
F22K18.70Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP- glucose; Belongs to the ADPRibase-Mn family. (311 aa)
DHAPRDGlycerol-3-phosphate dehydrogenase [NAD(+)] 1, chloroplastic; Involved in glycerolipid metabolism; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (400 aa)
GDPD6Glycerophosphodiester phosphodiesterase GDPD6. (372 aa)
PAH1Phosphatidate phosphatase PAH1; Magnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH2 to repress phospholipid biosynthesis at the endoplasmic reticulum (ER). May function indirectly as repressor of multiple enzymes involved in phospholipid biosynthesis. Is involved in the pathway of galactolipid synthesis in the ER, which is required for the membrane lipid remodeling, an essential adaptation mechanism to cope with phosphate starvation; Belongs to the lipin family. (904 aa)
GDPD1Glycerophosphodiester phosphodiesterase GDPD1, chloroplastic; Hydrolyzes glycerolphosphoglycerol, glycerophosphocholine and glycerophosphoethanolamine in vitro. May be involved in release of inorganic phosphate (Pi) from phospholipids during Pi starvation. Belongs to the glycerophosphoryl diester phosphodiesterase family. (361 aa)
GPAT1Glycerol-3-phosphate acyltransferase 1; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Involved in pollen development, by being required for tapetum differentiation and male fertility. In addition to the sporophytic effect, it also exerts a gametophytic effect on pollen performance. Belongs to the GPAT/DAPAT family. (585 aa)
NPC4Non-specific phospholipase C4; Non-specific phospholipase C (PLC) which assumes major PLC activity during inorganic phosphate starvation. Substrate preference is phosphatidylcholine (PC), but can also hydrolyze phosphatidylethanolamine (PE) with lower efficiency. Has no activity toward phosphatidic acid (PA). Plays an important role in the supply of both inorganic phosphate and diacylglycerol from membrane-localized phospholipids during phosphate deprivation. May be required for lipid- derived signaling molecules that positively modulate abscisic acid (ABA) response and promote plant t [...] (538 aa)
SDP6Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Required for glycerol catabolism and involved in NADH/NAD(+) homeostasis. Essential for postgerminative growth and seedling establishment. (629 aa)
PLDALPHA2Phospholipase D alpha 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action and response to stress, characterized by acidification of the cell. (810 aa)
LPAT31-acyl-sn-glycerol-3-phosphate acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. Has preference for C- 18-CoA substrates compared to C-16-CoA substrates; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (376 aa)
GPAT3Probable glycerol-3-phosphate acyltransferase 3; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Belongs to the GPAT/DAPAT family. (520 aa)
F17A8.110Probable choline kinase 3; Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity). (346 aa)
PLDGAMMA2Phospholipase D gamma 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine but prefers ethanolamine- containing lipids as substrates. Can use phosphatidylcholine (PC) as substrates in the presence of phosphatidylethanolamine (PE) and PIP2. Involved in membrane lipid modulation und [...] (856 aa)
PLDGAMMA3Phospholipase D gamma 3; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine but prefers ethanolamine- containing lipids as substrates. (866 aa)
PLDGAMMA1Phospholipase D gamma 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine (PS) and phosphatidylethanolamine (PE) as substrates only in the presence of PIP2. Can use phosphatidylcholine (PC), phosphatidylglycerol (PG) or N- acylphosphatidylethanolamine (NAPE) as substrates in the [...] (858 aa)
LPP2Lipid phosphate phosphatase 2; May play a general 'housekeeping role' in lipid metabolism. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities with no preference for either substrate. May play a role downstream of the ABA signaling pathway during seed germination and in stomatal movement in leaves. Belongs to the PA-phosphatase related phosphoesterase family. (290 aa)
LPP1Lipid phosphate phosphatase 1; Plays a general role in cellular responses to stress, may be by attenuating the signal produced by phospholipases. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities. Substrate preference is diacylglycerol pyrophosphate > phosphatidate; Belongs to the PA-phosphatase related phosphoesterase family. (327 aa)
CCT1-2Choline-phosphate cytidylyltransferase 1; Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine. Catalyzes the formation of CDP- choline. (332 aa)
At1g78690pN-acylphosphatidylethanolamine synthase; Acyltransferase that catalyzes the N-acylation of phosphatidylethanolamine to form N-acylphosphatidylethanolamine (N- acyl-PE) (e.g. NAPEs containing C16:0, C16:1, C18:0, and C18:1). Mediates also the formation of acylphosphatidylglycerol (acyl-PG) from lysoglycerophospholipid by O-acylation. Uses acyl-CoA as acyl donors. Acylates 1-acyllysophosphatidylethanolamine (1-acyllyso-PE) and 1- acyllysophosphatidylglycerol (1-acyllyso-PG) at the sn-2-position. (284 aa)
PECT1Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. Essential for early embryonic development. Belongs to the cytidylyltransferase family. (421 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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