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| | VPS35C | Vacuolar protein sorting-associated protein 35C; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins (By similarity). The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (790 aa) |
| | ARPC5B | Actin-related protein 2/3 complex subunit 5B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (135 aa) |
| | EHD2 | EH domain-containing protein 2; Involved in endocytosis negative regulation, probably by influencing actin organization. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Exhibits an inhibitory effect on endocytosis when over-expressed. (546 aa) |
| | F23M19.10 | Regulator of Vps4 activity in the MVB pathway protein. (649 aa) |
| | T23G18.12 | Vacuolar protein sorting-associated protein. (132 aa) |
| | ARFD1B | ADP-ribosylation factor D1B. (190 aa) |
| | BRO1 | Vacuolar-sorting protein BRO1; Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable). Associates with FREE1 and ELC to perform function in the ESCRT-I complex. Binds ubiquitin in vitro. Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs). Required for the endosomal location of AMSH3. Mediates high-affinity phosphate transporter trafficking to maintain phos [...] (846 aa) |
| | F8K7.4 | Calcium-binding EF hand family protein. (1247 aa) |
| | VPS35B | Vacuolar protein sorting-associated protein 35B; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26- VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (790 aa) |
| | F4ICV8_ARATH | Regulator of Vps4 activity in the MVB pathway protein. (347 aa) |
| | F6F22.26 | Regulator of Vps4 activity in the MVB pathway protein. (937 aa) |
| | F13I13.6 | Ubiquitin-conjugating enzyme/RWD-like protein. (331 aa) |
| | ARPC2B | Actin-related protein 2/3 complex subunit 2B; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development (By similarity). (374 aa) |
| | F4IX33_ARATH | SNF7 family protein. (462 aa) |
| | BIG4 | Brefeldin A-inhibited guanine nucleotide-exchange protein 4; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting (By similarity). (1706 aa) |
| | F17A13.260 | Regulator of Vps4 activity in the MVB pathway protein. (1090 aa) |
| | F8D20.240 | Regulator of Vps4 activity in the MVB pathway protein. (466 aa) |
| | P85 | Senescence/dehydration-associated protein At4g35985, chloroplastic. (448 aa) |
| | BIG1 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting (By similarity). (1687 aa) |
| | ARPC4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (169 aa) |
| | GNL2 | ARF guanine-nucleotide exchange factor GNL2; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Essential for pollen germination. (1375 aa) |
| | RABG3B | Ras-related protein RABG3b; Intracellular vesicle trafficking and protein transport. Functions in autophagy. Involved in xylem and tracheary element differentiation. (203 aa) |
| | RABA2A | Ras-related protein RABA2a; Intracellular vesicle trafficking and protein transport. (217 aa) |
| | PLDBETA2 | Phospholipase D beta 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine or N- acylphosphatidylethanolamine as substrates; Belongs to the phospholipase D family. C2-PLD subfamily. (927 aa) |
| | AP2M | AP-2 complex subunit mu; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. AP-2 recognizes Y-X-X-Phi endocytosis signal motif within th [...] (438 aa) |
| | RABE1A | Ras-related protein RABE1a; Involved in membrane trafficking from the Golgi to the plasma membrane; Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | PIP5K3 | Phosphatidylinositol 4-phosphate 5-kinase 3. (705 aa) |
| | ERD7 | Protein EARLY-RESPONSIVE TO DEHYDRATION 7, chloroplastic. (452 aa) |
| | VPS45 | Vacuolar protein sorting-associated protein 45 homolog; Involved in the protein transport to the vacuole, probably at the level of vesicle fusion at the trans-Golgi network (TGN) and not in transport from the TGN to the prevacuolar compartment. Binds syntaxins. (569 aa) |
| | VPS28-1 | Vacuolar protein sorting-associated protein 28 homolog 1; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity); Belongs to the VPS28 family. (209 aa) |
| | HSP70-3 | Heat shock 70 kDa protein 3; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (649 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit 1A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (378 aa) |
| | AGD7 | ADP-ribosylation factor GTPase-activating protein AGD7; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in protein trafficking by controlling ARF1 activity; may participate in COPI vesicle formation at the Golgi complex. (456 aa) |
| | AGD10 | ADP-ribosylation factor GTPase-activating protein AGD10; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Activates ARF1 and ARF2. Required for female gametophyte development. Involved in root hair and pollen tube growth. (395 aa) |
| | VPS32.1 | Vacuolar protein sorting-associated protein 32 homolog 1; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity); Belongs to the SNF7 family. (213 aa) |
| | CPA-2 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (308 aa) |
| | ARF2-B | ADP-ribosylation factor 2-B; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. (181 aa) |
| | HSP70-1 | Heat shock 70 kDa protein 1; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Probably involved in defense response. Chaperone involved in protein targeting to chloroplasts. May cooperate with SGT1 and HSP90 in R gene-mediated resistance towards the oomycete Hyaloperonospora parasitica (downy mildew). Plays a role with WPP-domain proteins in facilitating WIT1 nuclear [...] (651 aa) |
| | HSP70-2 | Heat shock 70 kDa protein 2; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (653 aa) |
| | RABE1C | Ras-related protein RABE1c; Involved in membrane trafficking from the Golgi to the plasma membrane; Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | RABA5C | Ras-related protein RABA5c; Intracellular vesicle trafficking and protein transport. Binds GTP and GDP and possesses intrinsic GTPase activity. (214 aa) |
| | ARF1 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; required for the sequence-specific vacuolar sorting route to the lytic vacuole, for the ER-to-Golgi transport and for the Golgi-derived transport to the plasma membrane. Involved in the recruitment of COPI and GDAP1 to membranes. Required for recycling of PIN auxin transporters (e.g. PIN1 and PIN2) in a fungal toxin brefeldin A (BFA)- dependent manner. Involved in various auxin-dependent developmental processes. Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | PLDALPHA3 | Phospholipase D alpha 3; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Active with phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and phosphatidylserine (PS) as substrates. No activity toward phosphatidylinositol (PI) or PIP2. Positively mediates plant responses to hyperosmotic stresses and promotes root growth, flowering, and stress avoidance. Not involved in the abscisic acid regulation of stomatal movement and transpirational water loss. Belongs to the phospholipase D family. C2-PLD s [...] (820 aa) |
| | PLDBETA1 | Phospholipase D beta 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Involved in regulating stomatal movement and plant-water status. Can use phosphatidylserine (PS) and phosphatidylethanolamine (PE) as substrates only in the presence of PIP2. Can use phosphatidylcholine (PC), phosphatidylglycerol (PG) [...] (1083 aa) |
| | CHC2 | Clathrin heavy chain 2; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). Mediates endocytosis and is required for a correct polar distribution of PIN auxin transporters. (1703 aa) |
| | CHC1 | Clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). Mediates endocytosis and is required for a correct polar distribution of PIN auxin transporters. Belongs to the clathrin heavy chain family. (1705 aa) |
| | AGD15 | Probable ADP-ribosylation factor GTPase-activating protein AGD15; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (232 aa) |
| | VPS2.2 | Vacuolar protein sorting-associated protein 2 homolog 2; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity). (222 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (174 aa) |
| | PLDALPHA1 | Phospholipase D alpha 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action and response to stress, characterized by acidification of the cell. Involved in wound induction of jasmonic acid. May be involved in membrane lipid remodeling. Probably involved in freezing tolerance by modulating the cold-responsive genes and accumulation of osmolytes. Can use phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) as subst [...] (810 aa) |
| | RABA1B | Ras-related protein RABA1b; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | VPS37-2 | Vacuolar protein-sorting-associated protein 37 homolog 2; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (By similarity). (218 aa) |
| | GN | ARF guanine-nucleotide exchange factor GNOM; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of endosomal vesicle trafficking but is also involved in the endocytosis process. Could function redundantly with GNL1 in the retrograde Golgi to endoplasmic reticulum trafficking. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the sorting of PIN1 from endosomal compartments to the basal pla [...] (1451 aa) |
| | PIP5K1 | Phosphatidylinositol 4-phosphate 5-kinase 1; Catalyzes the synthesis of phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4-bisphosphate. (752 aa) |
| | VP22-1 | Vacuolar protein sorting-associated protein 22 homolog 1; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT- III complex (By similarity). (250 aa) |
| | AMSH3 | AMSH-like ubiquitin thioesterase 3; Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains, but is not implicated in protein degradation by the 26S proteasome, deneddylation, or desumoylation. Required for intracellular trafficking (e.g. trafficking from the Golgi to the vacuole and the vacuolar trafficking of endocytosed cargo), endocytosis and vacuole biogenesis; Belongs to the peptidase M67C family. (507 aa) |
| | AGD3 | ADP-ribosylation factor GTPase-activating protein AGD3; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Involved in the spatial control of provascular differentiation. Required for the formation of the normal pattern of continuous secondary veins. Involved in auxin signaling but not in polar auxin transport or in auxin responses. Required for PIN1 internalization in roots. (827 aa) |
| | EPSIN2 | Clathrin interactor EPSIN 2; May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly (By similarity). Binds to membranes enriched in phosphatidylinositol 3- phosphate (PtdIns(3)P). Plays an important role in protein trafficking. (895 aa) |
| | ARFA1F | Similar to ADP-ribosylation factor gb|AAD17207; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | AMSH2 | AMSH-like ubiquitin thioesterase 2; Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains; Belongs to the peptidase M67C family. (223 aa) |
| | VPS35A | Vacuolar protein sorting-associated protein 35A; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins (Probable). Binds alone to endosomal membranes and is required for recruitment of VPS26 and VPS29 to membrane. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (787 aa) |
| | AP17 | AP-2 complex subunit sigma; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides (By similarity). (142 aa) |
| | VPS20.1 | Vacuolar protein sorting-associated protein 20 homolog 1; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity). (219 aa) |
| | AGD8 | Probable ADP-ribosylation factor GTPase-activating protein AGD8; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (413 aa) |
| | PIP5K2 | Phosphatidylinositol 4-phosphate 5-kinase 2; Possesses phosphatidylinositol kinase activity in vitro. (754 aa) |
| | AGD11 | Probable ADP-ribosylation factor GTPase-activating protein AGD11; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (385 aa) |
| | PIP5K9 | Phosphatidylinositol 4-phosphate 5-kinase 9; Plays a role in sugar-mediated root development. Interaction with CINV1 induces repression of CINV1 activity and negative regulation of sugar-mediated root cell elongation. (815 aa) |
| | CHMP1A | ESCRT-related protein CHMP1A; Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth. Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm. (203 aa) |
| | AGD13 | Probable ADP-ribosylation factor GTPase-activating protein AGD13; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (336 aa) |
| | ARPC2A | Actin-related protein 2/3 complex subunit 2A; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the ARPC2 family. (318 aa) |
| | ALPHAC-AD | AP-2 complex subunit alpha-2; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides. (1013 aa) |
| | ALPHA-ADR | AP-2 complex subunit alpha-1; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides (By similarity). (1012 aa) |
| | PIP5K8 | Phosphatidylinositol 4-phosphate 5-kinase 8. (769 aa) |
| | EPSIN1 | Clathrin interactor EPSIN 1; May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly (By similarity). Does not seem to bind to phospholipids. Plays an important role in the vacuolar trafficking of soluble cargo proteins at the trans-Golgi network; Belongs to the epsin family. (560 aa) |
| | AMSH1 | AMSH-like ubiquitin thioesterase 1; Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains; Belongs to the peptidase M67C family. (507 aa) |
| | VPS25 | Vacuolar protein sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT- III complex (By similarity); Belongs to the VPS25 family. (179 aa) |
| | EPSIN3 | Clathrin interactor EPSIN 3; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly (By similarity). (1024 aa) |
| | VPS2.3 | Vacuolar protein sorting-associated protein 2 homolog 3; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity). (210 aa) |
| | RABG3A | Ras-related protein RABG3a; Intracellular vesicle trafficking and protein transport. (206 aa) |
| | EHD1 | EH domain-containing protein 1; Involved in endocytosis positive regulation. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Confers salt tolerance. (545 aa) |
| | RABA2C | Ras-related protein RABA2c; Intracellular vesicle trafficking and protein transport. (217 aa) |
| | PLDDELTA | Phospholipase D delta; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). May be involved in PA accumulation in the dehydration stress response and in the transduction of hormonal and environmental signals to the microtubules cytoskeleton. Prefers phosphatidylethanolamine to phosphatidylcholine as substrate. Involved in H(2)O(2) and abscisic acid (ABA)-induced stomatal closure. Involved in nitric oxide (NO) signaling during stomatal closure. Plays a positive role in ABA-promoted senescence. Involved in basal defense and nonhost [...] (868 aa) |
| | AGD2-2 | ADP-ribosylation factor GTPase-activating protein AGD2; Probable GTPase-activating protein. (776 aa) |
| | F2J7.16 | Regulator of Vps4 activity in the MVB pathway protein. (323 aa) |
| | HSP70-18 | Heat shock 70 kDa protein 18; Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (617 aa) |
| | RABG3D | Ras-related protein RABG3d; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (206 aa) |
| | PLDALPHA4 | Phospholipase D alpha 4; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Promotes growth and plays a role in nitrogen signaling. (762 aa) |
| | RABA4C | Ras-related protein RABA4c; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (223 aa) |
| | VPS36 | Vacuolar protein sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT- III complex (By similarity); Belongs to the VPS36 family. (440 aa) |
| | VPS24-1 | Vacuolar protein sorting-associated protein 24 homolog 1; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity). (229 aa) |
| | ELCL | Protein ELC-like; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs); Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily. (368 aa) |
| | SNX1 | Sorting nexin 1; Plays a role in vesicular protein sorting. Acts at the crossroads between the secretory and endocytic pathways. Is involved in the endosome to vacuole protein transport via its interaction with the BLOS1/2 proteins and, as component of the membrane-associated retromer complex, is also involved in endosome-to-Golgi retrograde transport. Required for the auxin-carrier protein PIN2 sorting to the lytic vacuolar pathway and the trafficking of several plasma membrane proteins. Also involved in the efficient sorting of seed storage protein globulin 12S. (402 aa) |
| | RABA5A | Ras-related protein RABA5a; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (221 aa) |
| | RABA2D | Ras-related protein RABA2d; Intracellular vesicle trafficking and protein transport. (217 aa) |
| | AGD9 | Probable ADP-ribosylation factor GTPase-activating protein AGD9; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (402 aa) |
| | AGD1 | ADP-ribosylation factor GTPase-activating protein AGD1; Probable GTPase-activating protein (By similarity). Regulator of membrane trafficking. Required for maintaining a straight growth of root hairs. (828 aa) |
| | VPS26A | Vacuolar protein sorting-associated protein 26A; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (302 aa) |
| | MMN10.12 | Ras-related small GTP-binding family protein. (216 aa) |
| | RABA1F | Ras-related protein RABA1f; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (217 aa) |
| | RABA4A | Ras-related protein RABA4a; Intracellular vesicle trafficking and protein transport. (226 aa) |
| | RABA1C | Ras-related protein RABA1c; Intracellular vesicle trafficking and protein transport. (216 aa) |
| | AGD5 | ADP-ribosylation factor GTPase-activating protein AGD5; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Mediates clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network (TGN). Promotes plant growth. Involved in the regulation of membrane trafficking and cell separation during floral organ shedding and abscission. Prevents abscission zone (AZ) cells enlargement. Exhibits ARF-GTPase activity toward ARF1 at TGN. (483 aa) |
| | GNL1 | ARF guanine-nucleotide exchange factor GNL1; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of retrograde Golgi to endoplasmic reticulum trafficking but is also involved in the endocytosis process. Could function redundantly with GNOM. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the endocytosis of PIN2 from plasma membrane to endosomal compartments. Required for maintenance of e [...] (1443 aa) |
| | VPS60-2 | Vacuolar protein sorting-associated protein 60.2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. (235 aa) |
| | AGD12 | ADP-ribosylation factor GTPase-activating protein AGD12; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). Binds phosphatidylinositol 3-monophosohate (PI-3-P) and anionic phospholipids. (337 aa) |
| | VPS20.2 | Vacuolar protein sorting-associated protein 20 homolog 2; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity); Belongs to the SNF7 family. (216 aa) |
| | ARFB1B | ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family. (192 aa) |
| | RABA4D | Ras-related protein RABA4d; Intracellular vesicle trafficking and protein transport. Plays an important role in the regulation of pollen tube tip growth. (222 aa) |
| | HSP70-4 | Heat shock 70 kDa protein 4; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). ATP-dependent molecular chaperone that assists folding of unfolded or misfolded proteins under stress conditions. Mediates plastid precursor degradation to prevent cytosolic precursor accumulation, together with the E3 ubiquitin-protein ligase CHIP. Recognizes specific sequence motifs in tr [...] (650 aa) |
| | ELC | Protein ELC; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). May control nuclear division through the microtubule cytoskeleton; Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily. (398 aa) |
| | PIP5K10 | Phosphatidylinositol 4-phosphate 5-kinase 10. (427 aa) |
| | RABA3 | Ras-related protein RABA3; Intracellular vesicle trafficking and protein transport. (237 aa) |
| | BIG3 | Brefeldin A-inhibited guanine nucleotide-exchange protein 3; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting (By similarity). Involved both in the nuclear division phase and in the nuclear fusion phase. (1750 aa) |
| | VPS60-1 | Vacuolar protein sorting-associated protein 60.1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs; Belongs to the SNF7 family. (235 aa) |
| | DRP2B | Dynamin-2B; Putative microtubule-associated force-producing protein, able to bind and hydrolyze GTP. (920 aa) |
| | PLDZETA1 | Phospholipase D zeta 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective. Regulates root-hair morphogenesis. Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus-starved roots. Involved in root elongation during phosphate limitation. (1096 aa) |
| | RABG3F | Ras-related protein RABG3f; Essential for trafficking from prevacuolar compartments to vacuoles. Involved in the trafficking of newly synthesized protein to vacuoles. Essential for plant growth. Participates in the recruitment of the core retromer components to the endosomal membrane by interacting with VPS35A. (206 aa) |
| | HSP70-7 | Heat shock 70 kDa protein 7, chloroplastic; Acts redundantly with HSP70-6 in the thermotolerance of germinating seeds. Plays an important role in the protein precursor import into chloroplasts; Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily. (718 aa) |
| | RABG3C | Ras-related protein RABG3c; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (206 aa) |
| | VPS24-2 | Putative vacuolar protein sorting-associated protein 24 homolog 2; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity); Belongs to the SNF7 family. (200 aa) |
| | ARFA1B | ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family. (188 aa) |
| | RABE1D | Ras-related protein RABE1d; Involved in membrane trafficking from the Golgi to the plasma membrane; Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | BIG2 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting (By similarity). (1793 aa) |
| | ARPC5A | Actin-related protein 2/3 complex subunit 5A; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (132 aa) |
| | PIP5K11 | Putative phosphatidylinositol 4-phosphate 5-kinase 11. (401 aa) |
| | PIP5K4 | Phosphatidylinositol 4-phosphate 5-kinase 4. (779 aa) |
| | T17J13.250 | ADP-ribosylation factor-like protein; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | AGD6 | Probable ADP-ribosylation factor GTPase-activating protein AGD6; GTPase-activating protein (GAP) for ADP ribosylation factor (ARF). (459 aa) |
| | CPB | Probable F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (256 aa) |
| | ARFB1C | Putative ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (192 aa) |
| | PLPZETA2 | Phospholipase D zeta 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective. Regulates vesicle trafficking and auxin responses. Required for the normal cycling of PIN-2 containing vesicles. Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus- starved roots. Involved in root elongation during phosphate limitation. Belongs to the phospholipase D family. PXPH-PLD subfamily. (1046 aa) |
| | HSP70-5 | Heat shock 70 kDa protein 5; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. (646 aa) |
| | VPS28-2 | Vacuolar protein sorting-associated protein 28 homolog 2; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity); Belongs to the VPS28 family. (210 aa) |
| | VPS37-1 | Vacuolar protein-sorting-associated protein 37 homolog 1; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (By similarity); Belongs to the VPS37 family. (217 aa) |
| | F24M12.290 | Senescence/dehydration-associated protein At3g51250. (463 aa) |
| | DRP2A | Dynamin-2A; Microtubule-associated force-producing protein involved in clathrin-mediated vesicle trafficking from the trans-Golgi network to the central vacuole. Able to bind and hydrolyze GTP. Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (914 aa) |
| | RABE1E | Ras-related protein RABE1e; Involved in membrane trafficking from the Golgi to the plasma membrane. (218 aa) |
| | PIP5K6 | Phosphatidylinositol 4-phosphate 5-kinase 6. (715 aa) |
| | ARFB1A | Probable ADP-ribosylation factor At2g15310; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (205 aa) |
| | RABA5D | Ras-related protein RABA5d; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (219 aa) |
| | RABG2 | Ras-related protein RABG2; Intracellular vesicle trafficking and protein transport. (212 aa) |
| | ARPC1B | Actin-related protein 2/3 complex subunit 1B; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development; Belongs to the WD repeat ARPC1 family. (378 aa) |
| | VPS2.1 | Vacuolar protein sorting-associated protein 2 homolog 1; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity); Belongs to the SNF7 family. (225 aa) |
| | PIP5K5 | Phosphatidylinositol 4-phosphate 5-kinase 5. (772 aa) |
| | RABA4B | Ras-related protein RABA4b; Regulator of membrane trafficking. May be required for secretion of cell wall components in cells; Belongs to the small GTPase superfamily. Rab family. (224 aa) |
| | AGD4 | ADP-ribosylation factor GTPase-activating protein AGD4; Probable GTPase-activating protein. (775 aa) |
| | RABA1D | Ras-related protein RABA1d; Intracellular vesicle trafficking and protein transport. (214 aa) |
| | F12A12.60 | ENTH/VHS family protein. (307 aa) |
| | CHMP1B | ESCRT-related protein CHMP1B; Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth. Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm. Belongs to the SNF7 family. (203 aa) |
| | PLDALPHA2 | Phospholipase D alpha 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action and response to stress, characterized by acidification of the cell. (810 aa) |
| | T4C9.70 | Alpha/beta-Hydrolases superfamily protein. (392 aa) |
| | VPS29 | Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. Required for the auxin-carrier protein PIN2 sorting to the lytic vacuolar pathway and the PIN1 recycling to the plasma membrane. Also involved in the efficient sorting of seed storage proteins globulin 12S and albumin 2S. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (190 aa) |
| | HSP70-6 | Heat shock 70 kDa protein 6, chloroplastic; Acts redundantly with HSP70-7 in the thermotolerance of germinating seeds. Plays an important role in the protein precursor import into chloroplasts. (718 aa) |
| | PIP5K7 | Phosphatidylinositol 4-phosphate 5-kinase 7. (754 aa) |
| | LIP5 | Protein HOMOLOG OF MAMMALIAN LYST-INTERACTING PROTEIN 5; Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). Thought to be a cofactor of SKD1/VPS4, which catalyzes the disassembly of membrane-associated ESCRT-III. Target of pathogen-responsive mitogen-activated protein kinases (MPKs) that plays a critical role in plant basal resistance to Pseudomonas syrin [...] (421 aa) |
| | VPS32.2 | Vacuolar protein sorting-associated protein 32 homolog 2; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity). (219 aa) |
| | PLDGAMMA2 | Phospholipase D gamma 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine but prefers ethanolamine- containing lipids as substrates. Can use phosphatidylcholine (PC) as substrates in the presence of phosphatidylethanolamine (PE) and PIP2. Involved in membrane lipid modulation und [...] (856 aa) |
| | PLDGAMMA3 | Phospholipase D gamma 3; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine but prefers ethanolamine- containing lipids as substrates. (866 aa) |
| | PLDGAMMA1 | Phospholipase D gamma 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine (PS) and phosphatidylethanolamine (PE) as substrates only in the presence of PIP2. Can use phosphatidylcholine (PC), phosphatidylglycerol (PG) or N- acylphosphatidylethanolamine (NAPE) as substrates in the [...] (858 aa) |
| | VPS26B | Vacuolar protein sorting-associated protein 26B; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. (303 aa) |
| | SKD1 | Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1; Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex. May also regulate cell cycle. Required during seed development for the formation of mucilage in seed coat and testa. Involved in the maintenance of Na(+)/K(+) homeostasis under salt stress. Required for cell expansion. (435 aa) |
