STRINGSTRING
SEH52075.1 SEH52075.1 SEH47498.1 SEH47498.1 SEH47985.1 SEH47985.1 SEH48178.1 SEH48178.1 SEH48186.1 SEH48186.1 SEH48190.1 SEH48190.1 SEH48336.1 SEH48336.1 SEH48815.1 SEH48815.1 SEH92173.1 SEH92173.1 SEH91992.1 SEH91992.1 SEH91768.1 SEH91768.1 SEH91682.1 SEH91682.1 SEH91429.1 SEH91429.1 SEH91424.1 SEH91424.1 SEH91419.1 SEH91419.1 SEH90349.1 SEH90349.1 SEH90187.1 SEH90187.1 SEH89833.1 SEH89833.1 SEH89562.1 SEH89562.1 SEH88417.1 SEH88417.1 SEH88202.1 SEH88202.1 SEH47002.1 SEH47002.1 SEH86995.1 SEH86995.1 SEH86806.1 SEH86806.1 rnhB rnhB pnp pnp SEH84006.1 SEH84006.1 dut dut SEH83216.1 SEH83216.1 SEH82472.1 SEH82472.1 SEH82025.1 SEH82025.1 SEH78235.1 SEH78235.1 SEH77377.1 SEH77377.1 SEH76760.1 SEH76760.1 SEH76650.1 SEH76650.1 SEH76525.1 SEH76525.1 SEH76399.1 SEH76399.1 SEH76333.1 SEH76333.1 SEH75143.1 SEH75143.1 SEH92428.1 SEH92428.1 SEH92589.1 SEH92589.1 SEH92919.1 SEH92919.1 SEH69781.1 SEH69781.1 deaD deaD SEH68655.1 SEH68655.1 SEH68491.1 SEH68491.1 xseA xseA xseB xseB SEH66439.1 SEH66439.1 rnhA rnhA SEH64860.1 SEH64860.1 SEH64384.1 SEH64384.1 SEH64147.1 SEH64147.1 SEH63729.1 SEH63729.1 SEH62931.1 SEH62931.1 SEH62525.1 SEH62525.1 SEH62474.1 SEH62474.1 SEH62463.1 SEH62463.1 SEH62446.1 SEH62446.1 SEH62440.1 SEH62440.1 SEH62111.1 SEH62111.1 SEH61975.1 SEH61975.1 SEH61968.1 SEH61968.1 SEH61958.1 SEH61958.1 SEH61863.1 SEH61863.1 SEH61435.1 SEH61435.1 SEH61424.1 SEH61424.1 SEH61412.1 SEH61412.1 SEH61397.1 SEH61397.1 SEH60969.1 SEH60969.1 SEH58940.1 SEH58940.1 SEH58928.1 SEH58928.1 SEH58919.1 SEH58919.1 SEH58845.1 SEH58845.1 SEH58782.1 SEH58782.1 SEH58764.1 SEH58764.1 SEH58706.1 SEH58706.1 SEH58476.1 SEH58476.1 SEH58457.1 SEH58457.1 SEH58280.1 SEH58280.1 SEH57664.1 SEH57664.1 SEH55834.1 SEH55834.1 SEH54827.1 SEH54827.1 SEH54311.1 SEH54311.1 SEH54097.1 SEH54097.1 SEH54088.1 SEH54088.1 SEH54082.1 SEH54082.1 SEH53875.1 SEH53875.1 SEH53362.1 SEH53362.1 SEH47470.1 SEH47470.1 SEH51686.1 SEH51686.1 SEH51349.1 SEH51349.1 deoC deoC SEH47027.1 SEH47027.1 SEH47035.1 SEH47035.1 SEH47272.1 SEH47272.1 SEH74205.1 SEH74205.1 SEH74082.1 SEH74082.1 SEH73756.1 SEH73756.1 SEH73276.1 SEH73276.1 SEH73184.1 SEH73184.1 SEH71522.1 SEH71522.1 mhpB mhpB mhpA mhpA SEH71472.1 SEH71472.1 SEH71012.1 SEH71012.1 rph rph
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEH52075.1Predicted amidohydrolase YtcJ. (431 aa)
SEH47498.1Predicted dithiol-disulfide isomerase, DsbA family. (238 aa)
SEH47985.1Esterase-like activity of phytase. (732 aa)
SEH48178.1Xanthine dehydrogenase YagT iron-sulfur-binding subunit. (171 aa)
SEH48186.1Xanthine dehydrogenase YagS FAD-binding subunit. (329 aa)
SEH48190.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (694 aa)
SEH48336.1HD domain-containing protein. (189 aa)
SEH48815.1Hypothetical protein. (535 aa)
SEH92173.1Purine nucleosidase. (346 aa)
SEH91992.12-polyprenyl-6-methoxyphenol hydroxylase. (505 aa)
SEH91768.1Cytidine deaminase. (136 aa)
SEH91682.1Amidohydrolase; Belongs to the peptidase M20A family. (393 aa)
SEH91429.1Xanthine dehydrogenase YagT iron-sulfur-binding subunit. (207 aa)
SEH91424.1Xanthine dehydrogenase YagS FAD-binding subunit. (324 aa)
SEH91419.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (722 aa)
SEH90349.1tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like. (231 aa)
SEH90187.1NAD+ diphosphatase. (308 aa)
SEH89833.14,5-epoxidase. (483 aa)
SEH89562.1Homogentisate 1,2-dioxygenase. (367 aa)
SEH88417.1Diguanylate cyclase (GGDEF) domain-containing protein. (614 aa)
SEH88202.1Hypothetical protein. (357 aa)
SEH47002.1Pimeloyl-ACP methyl ester carboxylesterase. (299 aa)
SEH86995.1Putative oxidoreductase. (276 aa)
SEH86806.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (262 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (241 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (751 aa)
SEH84006.1Pimeloyl-ACP methyl ester carboxylesterase. (340 aa)
dutdUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
SEH83216.1Diadenosine tetraphosphate (Ap4A) hydrolase. (190 aa)
SEH82472.1Uncharacterized conserved protein. (355 aa)
SEH82025.12-polyprenyl-6-methoxyphenol hydroxylase. (403 aa)
SEH78235.12-polyprenyl-6-methoxyphenol hydroxylase. (503 aa)
SEH77377.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (283 aa)
SEH76760.12,3-dihydroxybiphenyl 1,2-dioxygenase. (302 aa)
SEH76650.1Uncharacterized membrane protein YphA, DoxX/SURF4 family. (324 aa)
SEH76525.1Hypothetical protein. (529 aa)
SEH76399.12-polyprenyl-6-methoxyphenol hydroxylase. (355 aa)
SEH76333.1ATP-dependent RNA helicase HelY. (913 aa)
SEH75143.1Putative oxidoreductase. (174 aa)
SEH92428.1SnoaL-like domain-containing protein. (151 aa)
SEH92589.1Superfamily II DNA and RNA helicase. (428 aa)
SEH92919.1Hypothetical protein. (211 aa)
SEH69781.12-polyprenyl-6-methoxyphenol hydroxylase. (411 aa)
deaDATP-dependent RNA helicase CsdA; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (562 aa)
SEH68655.1Uncharacterized membrane protein YphA, DoxX/SURF4 family. (183 aa)
SEH68491.1Putative oxidoreductase. (173 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (409 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (68 aa)
SEH66439.1XTP/dITP diphosphohydrolase. (349 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (151 aa)
SEH64860.1Ham1 family protein. (212 aa)
SEH64384.12-polyprenyl-6-methoxyphenol hydroxylase. (378 aa)
SEH64147.1P-aminobenzoate N-oxygenase AurF. (337 aa)
SEH63729.12-polyprenyl-6-methoxyphenol hydroxylase. (394 aa)
SEH62931.1Hypothetical protein. (137 aa)
SEH62525.1Hypothetical protein. (337 aa)
SEH62474.1Xanthine dehydrogenase accessory factor. (370 aa)
SEH62463.1Carbon-monoxide dehydrogenase large subunit. (778 aa)
SEH62446.1Carbon-monoxide dehydrogenase medium subunit. (291 aa)
SEH62440.1Carbon-monoxide dehydrogenase small subunit. (156 aa)
SEH62111.1Acetyl-CoA acetyltransferase. (355 aa)
SEH61975.14-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (361 aa)
SEH61968.1Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (304 aa)
SEH61958.12-keto-4-pentenoate hydratase. (261 aa)
SEH61863.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
SEH61435.13-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9, 17-dione monooxygenase reductase component. (188 aa)
SEH61424.13,4-dihydroxy-9,10-secoandrosta-1,3, 5(10)-triene-9,17-dione 4,5-dioxygenase. (299 aa)
SEH61412.14,5:9,10-diseco-3-hydroxy-5,9, 17-trioxoandrosta-1(10),2-diene-4-oate hydrolase. (296 aa)
SEH61397.13-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9, 17-dione monooxygenase. (394 aa)
SEH60969.1Heme-degrading monooxygenase HmoA. (103 aa)
SEH58940.13-carboxy-cis,cis-muconate cycloisomerase. (401 aa)
SEH58928.1Protocatechuate 3,4-dioxygenase, alpha subunit. (189 aa)
SEH58919.1Protocatechuate 3,4-dioxygenase, beta subunit. (287 aa)
SEH58845.1Extradiol dioxygenase. (296 aa)
SEH58782.13-phenylpropionate/cinnamic acid dioxygenase, small subunit. (170 aa)
SEH58764.1Pimeloyl-ACP methyl ester carboxylesterase; Manually curated. (299 aa)
SEH58706.13-phenylpropionate/cinnamic acid dioxygenase, small subunit. (184 aa)
SEH58476.1Dioxygenase; Manually curated. (172 aa)
SEH58457.1Anthranilate 1,2-dioxygenase small subunit. (165 aa)
SEH58280.1Extradiol dioxygenase. (296 aa)
SEH57664.12-polyprenyl-6-methoxyphenol hydroxylase. (378 aa)
SEH55834.1Putative oxidoreductase. (177 aa)
SEH54827.1Hypothetical protein. (577 aa)
SEH54311.1SIR2-like domain-containing protein. (607 aa)
SEH54097.1Xanthine dehydrogenase YagS FAD-binding subunit. (328 aa)
SEH54088.1Xanthine dehydrogenase YagT iron-sulfur-binding subunit. (187 aa)
SEH54082.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (718 aa)
SEH53875.15'-nucleotidase. (256 aa)
SEH53362.1HD domain-containing protein. (222 aa)
SEH47470.1Toxin YoeB. (85 aa)
SEH51686.1NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family. (163 aa)
SEH51349.1Catechol 2,3-dioxygenase. (191 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (224 aa)
SEH47027.12-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (293 aa)
SEH47035.12-polyprenyl-6-methoxyphenol hydroxylase. (380 aa)
SEH47272.1Ribonuclease HI. (315 aa)
SEH74205.1dGTPase; Belongs to the dGTPase family. Type 2 subfamily. (430 aa)
SEH74082.1Hypothetical protein. (105 aa)
SEH73756.12-polyprenyl-6-methoxyphenol hydroxylase. (405 aa)
SEH73276.12-polyprenyl-6-methoxyphenol hydroxylase. (388 aa)
SEH73184.1HD domain-containing protein. (217 aa)
SEH71522.1Kynurenine formamidase. (331 aa)
mhpB2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (306 aa)
mhpA3-(3-hydroxy-phenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (563 aa)
SEH71472.12-hydroxy-6-oxonona-2,4-dienedioate hydrolase. (311 aa)
SEH71012.1XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (202 aa)
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (260 aa)
Your Current Organism:
Mycolicibacterium rutilum
NCBI taxonomy Id: 370526
Other names: CIP 109271, DSM 45405, JCM 16371, M. rutilum, Mycobacterium rutilum, Mycobacterium rutilum Hennessee et al. 2009, Mycobacterium sp. czh-107, Mycobacterium sp. czh-117, Mycobacterium sp. czh-132, Mycolicibacterium rutilum (Hennessee et al. 2009) Gupta et al. 2018, strain czh-117
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