STRINGSTRING
SEH92225.1 SEH92225.1 SEH64924.1 SEH64924.1 SEH64356.1 SEH64356.1 SEH62768.1 SEH62768.1 SEH62426.1 SEH62426.1 asd asd SEH59024.1 SEH59024.1 SEH58724.1 SEH58724.1 SEH58008.1 SEH58008.1 SEH58000.1 SEH58000.1 SEH57030.1 SEH57030.1 SEH56401.1 SEH56401.1 SEH56395.1 SEH56395.1 SEH55688.1 SEH55688.1 SEH55595.1 SEH55595.1 SEH70696.1 SEH70696.1 SEH54298.1 SEH54298.1 SEH53096.1 SEH53096.1 SEH52983.1 SEH52983.1 SEH52955.1 SEH52955.1 SEH51621.1 SEH51621.1 SEH50358.1 SEH50358.1 SEH49939.1 SEH49939.1 hemA hemA SEH49047.1 SEH49047.1 SEH47126.1 SEH47126.1 SEH87272.1 SEH87272.1 SEH87595.1 SEH87595.1 SEH88211.1 SEH88211.1 SEH89920.1 SEH89920.1 SEH91663.1 SEH91663.1 SEH70472.1 SEH70472.1 SEH92959.1 SEH92959.1 SEH72134.1 SEH72134.1 SEH72142.1 SEH72142.1 proA proA SEH76044.1 SEH76044.1 SEH76484.1 SEH76484.1 SEH76946.1 SEH76946.1 SEH77931.1 SEH77931.1 SEH78660.1 SEH78660.1 SEH79397.1 SEH79397.1 SEH81175.1 SEH81175.1 SEH81482.1 SEH81482.1 zwf zwf SEH81624.1 SEH81624.1 SEH81896.1 SEH81896.1 SEH82656.1 SEH82656.1 SEH84433.1 SEH84433.1 SEH84478.1 SEH84478.1 dapB dapB SEH84942.1 SEH84942.1 dxr dxr SEH85510.1 SEH85510.1 SEH85587.1 SEH85587.1 ilvC ilvC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEH92225.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (498 aa)
SEH64924.14-hydroxyacetophenone monooxygenase. (649 aa)
SEH64356.1Pyridine nucleotide-disulphide oxidoreductase. (459 aa)
SEH62768.13-hydroxyisobutyrate dehydrogenase. (282 aa)
SEH62426.13-hydroxyisobutyrate dehydrogenase. (295 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
SEH59024.1Hypothetical protein. (55 aa)
SEH58724.13-hydroxyisobutyrate dehydrogenase. (292 aa)
SEH58008.13-hydroxyisobutyrate dehydrogenase. (300 aa)
SEH58000.13-hydroxyisobutyrate dehydrogenase. (285 aa)
SEH57030.1Monooxygenase. (489 aa)
SEH56401.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (477 aa)
SEH56395.1NAD(P) transhydrogenase subunit alpha. (108 aa)
SEH55688.16-phosphogluconate dehydrogenase (decarboxylating). (297 aa)
SEH55595.1Thioredoxin reductase (NADPH). (323 aa)
SEH70696.1Dihydrofolate reductase. (199 aa)
SEH54298.1Dihydrofolate reductase. (201 aa)
SEH53096.1RibD C-terminal domain-containing protein. (214 aa)
SEH52983.1FAD dependent oxidoreductase. (349 aa)
SEH52955.1Nitroreductase. (221 aa)
SEH51621.1Assimilatory nitrite reductase (NAD(P)H) large subunit precursor; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (873 aa)
SEH50358.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (495 aa)
SEH49939.1Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (274 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (456 aa)
SEH49047.1Deazaflavin-dependent oxidoreductase, nitroreductase family. (150 aa)
SEH47126.1Putative flavoprotein involved in K+ transport. (420 aa)
SEH87272.1Nitroreductase. (224 aa)
SEH87595.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (499 aa)
SEH88211.1NADPH:quinone reductase. (343 aa)
SEH89920.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (491 aa)
SEH91663.1Dihydrolipoamide dehydrogenase. (471 aa)
SEH70472.1Homoserine dehydrogenase. (439 aa)
SEH92959.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (291 aa)
SEH72134.13-hydroxyisobutyrate dehydrogenase. (263 aa)
SEH72142.13-hydroxyisobutyrate dehydrogenase. (272 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (415 aa)
SEH76044.1Multimeric flavodoxin WrbA. (214 aa)
SEH76484.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (487 aa)
SEH76946.1Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD. (401 aa)
SEH77931.1Cytochrome P450. (439 aa)
SEH78660.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (487 aa)
SEH79397.1Dihydrofolate reductase. (214 aa)
SEH81175.13-oxoacyl-[acyl-carrier-protein] reductase. (254 aa)
SEH81482.1NADPH2:quinone reductase. (323 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (508 aa)
SEH81624.1Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
SEH81896.1Cyclohexanone monooxygenase. (493 aa)
SEH82656.1Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (313 aa)
SEH84433.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (163 aa)
SEH84478.1Hypothetical protein. (152 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (244 aa)
SEH84942.1Mycothione reductase. (471 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (392 aa)
SEH85510.1Cyclohexanone monooxygenase. (502 aa)
SEH85587.1Cytochrome P450. (410 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
Your Current Organism:
Mycolicibacterium rutilum
NCBI taxonomy Id: 370526
Other names: CIP 109271, DSM 45405, JCM 16371, M. rutilum, Mycobacterium rutilum, Mycobacterium rutilum Hennessee et al. 2009, Mycobacterium sp. czh-107, Mycobacterium sp. czh-117, Mycobacterium sp. czh-132, Mycolicibacterium rutilum (Hennessee et al. 2009) Gupta et al. 2018, strain czh-117
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