STRINGSTRING
SMC30037.1 SMC30037.1 SMC30038.1 SMC30038.1 SMC30040.1 SMC30040.1 SMC30125.1 SMC30125.1 SMC30165.1 SMC30165.1 SMC30179.1 SMC30179.1 SMC30180.1 SMC30180.1 SMC30183.1 SMC30183.1 fni fni SMC30191.1 SMC30191.1 SMC30194.1 SMC30194.1 SMC30195.1 SMC30195.1 SMC30248.1 SMC30248.1 SMC30257.1 SMC30257.1 SMC30259.1 SMC30259.1 SMC30263.1 SMC30263.1 SMC30265.1 SMC30265.1 SMC30267.1 SMC30267.1 SMC30269.1 SMC30269.1 zwf zwf SMC30304.1 SMC30304.1 acpP acpP SMC30461.1 SMC30461.1 SMC30551.1 SMC30551.1 SMC30557.1 SMC30557.1 SMC30583.1 SMC30583.1 SMC30596.1 SMC30596.1 SMC30597.1 SMC30597.1 SMC30599.1 SMC30599.1 pdhA pdhA SMC30629.1 SMC30629.1 SMC30633.1 SMC30633.1 SMC30636.1 SMC30636.1 rpiA rpiA SMC30648.1 SMC30648.1 SMC30651.1 SMC30651.1 galT galT galK galK SMC30682.1 SMC30682.1 SMC30683.1 SMC30683.1 SMC30684.1 SMC30684.1 SMC30685.1 SMC30685.1 SMC30686.1 SMC30686.1 SMC30687.1 SMC30687.1 lacD lacD SMC30692.1 SMC30692.1 SMC30701.1 SMC30701.1 SMC30708.1 SMC30708.1 SMC30718.1 SMC30718.1 SMC30768.1 SMC30768.1 SMC30814.1 SMC30814.1 SMC30887.1 SMC30887.1 SMC30895.1 SMC30895.1 SMC30919.1 SMC30919.1 SMC31001.1 SMC31001.1 SMC31007.1 SMC31007.1 SMC31023.1 SMC31023.1 ackA ackA SMC31896.1 SMC31896.1 SMC32434.1 SMC32434.1 SMC32911.1 SMC32911.1 SMC33042.1 SMC33042.1 SMC33106.1 SMC33106.1 SMC33197.1 SMC33197.1 SMC33223.1 SMC33223.1 SMC33236.1 SMC33236.1 SMC33248.1 SMC33248.1 SMC33414.1 SMC33414.1 SMC33428.1 SMC33428.1 SMC33456.1 SMC33456.1 SMC33540.1 SMC33540.1 SMC34266.1 SMC34266.1 eno eno gpmI gpmI tpiA tpiA pgk pgk SMC34298.1 SMC34298.1 SMC34330.1 SMC34330.1 SMC34456.1 SMC34456.1 SMC34508.1 SMC34508.1 SMC34548.1 SMC34548.1 SMC34796.1 SMC34796.1 SMC34804.1 SMC34804.1 SMC34816.1 SMC34816.1 SMC34824.1 SMC34824.1 SMC36005.1 SMC36005.1 SMC36234.1 SMC36234.1 SMC36315.1 SMC36315.1 SMC36514.1 SMC36514.1 SMC36560.1 SMC36560.1 SMC36573.1 SMC36573.1 SMC36995.1 SMC36995.1 SMC37019.1 SMC37019.1 pfkA pfkA SMC37507.1 SMC37507.1 pgi pgi SMC38842.1 SMC38842.1 SMC38923.1 SMC38923.1 SMC38984.1 SMC38984.1 SMC39378.1 SMC39378.1 SMC39395.1 SMC39395.1 SMC39399.1 SMC39399.1 SMC40137.1 SMC40137.1 SMC40550.1 SMC40550.1 SMC40559.1 SMC40559.1 SMC40567.1 SMC40567.1 SMC40753.1 SMC40753.1 SMC41796.1 SMC41796.1 SMC42138.1 SMC42138.1 SMC42471.1 SMC42471.1 ldh ldh prs prs glmU glmU SMC43569.1 SMC43569.1 SMC43616.1 SMC43616.1 SMC43963.1 SMC43963.1 SMC44347.1 SMC44347.1 SMC44509.1 SMC44509.1 SMC44520.1 SMC44520.1 nagB nagB glmS glmS glmM glmM rbsK rbsK SMC45865.1 SMC45865.1 SMC46064.1 SMC46064.1 SMC46072.1 SMC46072.1 SMC46101.1 SMC46101.1 SMC46171.1 SMC46171.1 SMC46206.1 SMC46206.1 lacD-2 lacD-2 SMC46224.1 SMC46224.1 SMC46258.1 SMC46258.1 SMC46276.1 SMC46276.1 SMC46310.1 SMC46310.1 SMC47321.1 SMC47321.1 SMC47353.1 SMC47353.1 SMC47582.1 SMC47582.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMC30037.1NADPH:quinone reductase. (320 aa)
SMC30038.1DNA-binding transcriptional regulator, MarR family. (144 aa)
SMC30040.1Fatty-acid peroxygenase; Belongs to the cytochrome P450 family. (419 aa)
SMC30125.1Transcriptional regulator, LacI family. (335 aa)
SMC30165.1Maltose O-acetyltransferase. (199 aa)
SMC30179.1Mevalonate kinase. (316 aa)
SMC30180.1Diphosphomevalonate decarboxylase. (334 aa)
SMC30183.1Phosphomevalonate kinase. (365 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (353 aa)
SMC30191.1Protein N-acetyltransferase, RimJ/RimL family. (176 aa)
SMC30194.1Phosphate acetyltransferase. (325 aa)
SMC30195.1Gluconate kinase, FGGY family. (484 aa)
SMC30248.1Glucokinase. (321 aa)
SMC30257.1Luciferase family oxidoreductase, group 1. (334 aa)
SMC30259.1Lipoate-protein ligase. (351 aa)
SMC30263.1NAD-dependent protein deacetylase, SIR2 family. (294 aa)
SMC30265.1O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain. (265 aa)
SMC30267.1Glycine cleavage system H protein. (110 aa)
SMC30269.12,4-dienoyl-CoA reductase. (406 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
SMC30304.1N-acetylglucosamine-6-phosphate deacetylase. (381 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa)
SMC30461.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
SMC30551.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (467 aa)
SMC30557.1Undecaprenyl-diphosphatase. (232 aa)
SMC30583.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1145 aa)
SMC30596.1Dihydrolipoamide dehydrogenase. (470 aa)
SMC30597.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (533 aa)
SMC30599.1Pyruvate dehydrogenase E1 component beta subunit. (323 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa)
SMC30629.1Iron-sulphur cluster biosynthesis; Belongs to the HesB/IscA family. (112 aa)
SMC30633.13-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (440 aa)
SMC30636.1hydroxymethylglutaryl-CoA synthase. (388 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
SMC30648.1Hypothetical protein. (251 aa)
SMC30651.1Xaa-Pro dipeptidase. (371 aa)
galTUDPglucose--hexose-1-phosphate uridylyltransferase. (501 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (393 aa)
SMC30682.1PTS system, mannose-specific IIA component. (134 aa)
SMC30683.1PTS system IID component, Man family. (268 aa)
SMC30684.1PTS system, mannose-specific IIC component. (299 aa)
SMC30685.1PTS system, mannose-specific IIB component. (160 aa)
SMC30686.1Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (592 aa)
SMC30687.1Transcriptional regulator, GntR family. (238 aa)
lacDTagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (330 aa)
SMC30692.1Galactosamine 6-phosphate isomerase AgaS. (392 aa)
SMC30701.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (347 aa)
SMC30708.1Tetratricopeptide repeat-containing protein. (328 aa)
SMC30718.1Transcriptional regulator, AraC family. (296 aa)
SMC30768.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
SMC30814.1UDPglucose 6-dehydrogenase. (388 aa)
SMC30887.1L-glutamine synthetase. (445 aa)
SMC30895.1Acetyl esterase/lipase. (322 aa)
SMC30919.1Phosphotransferase system, fructose-specific IIC component. (340 aa)
SMC31001.1Uncharacterized protein YxjI. (159 aa)
SMC31007.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
SMC31023.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
SMC31896.1Lysophospholipase, alpha-beta hydrolase superfamily. (307 aa)
SMC32434.1Aldo/keto reductase. (283 aa)
SMC32911.1Asparaginase. (329 aa)
SMC33042.1Pyruvate oxidase; Belongs to the TPP enzyme family. (591 aa)
SMC33106.1DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (305 aa)
SMC33197.1Maltose 6'-phosphate phosphatase. (275 aa)
SMC33223.1PTS system maltose-specific IIA component, Glc family /PTS system maltose-specific IIB component, Glc family /PTS system maltose-specific IIC component, Glc family. (725 aa)
SMC33236.1Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (754 aa)
SMC33248.14-alpha-glucanotransferase. (501 aa)
SMC33414.1PTS system, fructose-specific IIC component. (648 aa)
SMC33428.1Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (308 aa)
SMC33456.1Transcriptional regulator, DeoR family. (244 aa)
SMC33540.1Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
SMC34266.1AraC-type DNA-binding protein. (274 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
SMC34298.1Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
SMC34330.16-phosphogluconolactonase. (342 aa)
SMC34456.1PTS system IIA component, Glc family. (172 aa)
SMC34508.1Glycolate oxidase. (444 aa)
SMC34548.1NADPH-glutathione reductase. (449 aa)
SMC34796.1PTS system IIB component, Glc family /PTS system IIC component, Glc family. (521 aa)
SMC34804.1Maltose-6'-phosphate glucosidase. (441 aa)
SMC34816.1Transcriptional regulator, RpiR family. (247 aa)
SMC34824.1LysM domain-containing protein. (451 aa)
SMC36005.1UTP--glucose-1-phosphate uridylyltransferase. (291 aa)
SMC36234.1Lipoate-protein ligase A. (339 aa)
SMC36315.13alpha(or 20beta)-hydroxysteroid dehydrogenase. (243 aa)
SMC36514.1Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (148 aa)
SMC36560.1Phosphocarrier protein. (88 aa)
SMC36573.1Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
SMC36995.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (477 aa)
SMC37019.1Acylphosphatase. (92 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
SMC37507.1NADPH:quinone reductase. (325 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (448 aa)
SMC38842.1Alcohol dehydrogenase, propanol-preferring. (345 aa)
SMC38923.1Fructose-bisphosphate aldolase. (284 aa)
SMC38984.1Lipoate-protein ligase A. (282 aa)
SMC39378.1PTS system, glucose-like IIB component. (102 aa)
SMC39395.1Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (380 aa)
SMC39399.1Trehalose-6-phosphate hydrolase. (552 aa)
SMC40137.13-hydroxybutyryl-CoA dehydrogenase. (559 aa)
SMC40550.1Glyoxylase, beta-lactamase superfamily II. (332 aa)
SMC40559.1Glyoxylase, beta-lactamase superfamily II. (254 aa)
SMC40567.1Acyl-CoA dehydrogenase, N-terminal domain. (166 aa)
SMC40753.1LPXTG-motif cell wall anchor domain-containing protein. (510 aa)
SMC41796.1UDP-galactose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (339 aa)
SMC42138.1Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (457 aa)
SMC42471.13-hydroxybutyryl-CoA dehydrogenase. (302 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (332 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa)
SMC43569.1Alpha amylase, catalytic domain. (446 aa)
SMC43616.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
SMC43963.1Lactate oxidase. (371 aa)
SMC44347.1Mannose-6-phosphate isomerase, cupin superfamily. (140 aa)
SMC44509.1UTP--glucose-1-phosphate uridylyltransferase. (291 aa)
SMC44520.1Phosphoglucomutase. (575 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (234 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (454 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (294 aa)
SMC45865.1Transcriptional regulator, LacI family. (323 aa)
SMC46064.1Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family. (1534 aa)
SMC46072.1Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (311 aa)
SMC46101.1Galactose-6-phosphate isomerase lacB subunit. (172 aa)
SMC46171.1Galactose-6-phosphate isomerase lacA subunit. (142 aa)
SMC46206.1Transcriptional regulator, DeoR family. (252 aa)
lacD-2Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (332 aa)
SMC46224.1PTS system IIA component, Gat family. (165 aa)
SMC46258.1PTS system IIB component, Gat family. (99 aa)
SMC46276.1PTS system IIC component, Gat family. (470 aa)
SMC46310.16-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (482 aa)
SMC47321.13-hydroxybutyryl-CoA dehydrogenase. (591 aa)
SMC47353.1Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains. (228 aa)
SMC47582.1PTS system, D-glucosamine-specific IIC component. (728 aa)
Your Current Organism:
Aerococcus suis
NCBI taxonomy Id: 371602
Other names: Aerococcus suis Vela et al. 2007 emend. Tohno et al. 2014, CCUG 52530, CECT 7139, DSM 21500, JCM 18035
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