STRINGSTRING
SMC30280.1 SMC30280.1 zwf zwf SMC30269.1 SMC30269.1 SMC30248.1 SMC30248.1 SMC30203.1 SMC30203.1 SMC30195.1 SMC30195.1 SMC30194.1 SMC30194.1 SMC30161.1 SMC30161.1 mgsA mgsA SMC30056.1 SMC30056.1 folD folD SMC30037.1 SMC30037.1 pfkA pfkA SMC37019.1 SMC37019.1 SMC47321.1 SMC47321.1 SMC47007.1 SMC47007.1 SMC46049.1 SMC46049.1 SMC45995.1 SMC45995.1 SMC44533.1 SMC44533.1 SMC44520.1 SMC44520.1 SMC43616.1 SMC43616.1 prs prs ldh ldh SMC43044.1 SMC43044.1 SMC43001.1 SMC43001.1 SMC42509.1 SMC42509.1 SMC42471.1 SMC42471.1 SMC42138.1 SMC42138.1 SMC41943.1 SMC41943.1 SMC41858.1 SMC41858.1 fhs fhs SMC40669.1 SMC40669.1 SMC40567.1 SMC40567.1 SMC40333.1 SMC40333.1 SMC40137.1 SMC40137.1 SMC38923.1 SMC38923.1 SMC38842.1 SMC38842.1 pgi pgi SMC37822.1 SMC37822.1 SMC37756.1 SMC37756.1 SMC37507.1 SMC37507.1 SMC37337.1 SMC37337.1 scpB scpB SMC37119.1 SMC37119.1 SMC36995.1 SMC36995.1 SMC36514.1 SMC36514.1 SMC36061.1 SMC36061.1 SMC34816.1 SMC34816.1 SMC34508.1 SMC34508.1 SMC34330.1 SMC34330.1 SMC34323.1 SMC34323.1 SMC34298.1 SMC34298.1 pgk pgk tpiA tpiA gpmI gpmI eno eno SMC33540.1 SMC33540.1 SMC33487.1 SMC33487.1 SMC33414.1 SMC33414.1 SMC33060.1 SMC33060.1 SMC33012.1 SMC33012.1 SMC32968.1 SMC32968.1 ackA ackA SMC31023.1 SMC31023.1 SMC31007.1 SMC31007.1 SMC30957.1 SMC30957.1 SMC30949.1 SMC30949.1 SMC30946.1 SMC30946.1 SMC30919.1 SMC30919.1 SMC30887.1 SMC30887.1 SMC30785.1 SMC30785.1 SMC30780.1 SMC30780.1 SMC30768.1 SMC30768.1 SMC30751.1 SMC30751.1 SMC30701.1 SMC30701.1 rpiA rpiA pdhA pdhA SMC30599.1 SMC30599.1 SMC30597.1 SMC30597.1 SMC30596.1 SMC30596.1 SMC30583.1 SMC30583.1 SMC30551.1 SMC30551.1 SMC30461.1 SMC30461.1 SMC30398.1 SMC30398.1 SMC30305.1 SMC30305.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMC30280.1Phosphoesterase RecJ domain-containing protein. (311 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
SMC30269.12,4-dienoyl-CoA reductase. (406 aa)
SMC30248.1Glucokinase. (321 aa)
SMC30203.1Peptidase V. Metallo peptidase. MEROPS family M20A. (468 aa)
SMC30195.1Gluconate kinase, FGGY family. (484 aa)
SMC30194.1Phosphate acetyltransferase. (325 aa)
SMC30161.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (149 aa)
SMC30056.1Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (359 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
SMC30037.1NADPH:quinone reductase. (320 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
SMC37019.1Acylphosphatase. (92 aa)
SMC47321.13-hydroxybutyryl-CoA dehydrogenase. (591 aa)
SMC47007.1Succinyl-diaminopimelate desuccinylase. (413 aa)
SMC46049.1Uncharacterized NAD(P)/FAD-binding protein YdhS. (499 aa)
SMC45995.1c-di-AMP phosphodiesterase, consists of a GGDEF-like and DHH domains; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (674 aa)
SMC44533.1Conserved hypothetical protein, cofD-related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (353 aa)
SMC44520.1Phosphoglucomutase. (575 aa)
SMC43616.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (332 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)
SMC43044.1S1 RNA binding domain protein. (140 aa)
SMC43001.1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
SMC42509.1NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. (452 aa)
SMC42471.13-hydroxybutyryl-CoA dehydrogenase. (302 aa)
SMC42138.1Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (457 aa)
SMC41943.1Dipeptidase, putative. (444 aa)
SMC41858.1Carbamate kinase; Belongs to the carbamate kinase family. (313 aa)
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (558 aa)
SMC40669.1Catechol 2,3-dioxygenase. (284 aa)
SMC40567.1Acyl-CoA dehydrogenase, N-terminal domain. (166 aa)
SMC40333.1Serine O-acetyltransferase. (178 aa)
SMC40137.13-hydroxybutyryl-CoA dehydrogenase. (559 aa)
SMC38923.1Fructose-bisphosphate aldolase. (284 aa)
SMC38842.1Alcohol dehydrogenase, propanol-preferring. (345 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (448 aa)
SMC37822.1General stress protein 13. (129 aa)
SMC37756.14-nitrophenyl phosphatase. (264 aa)
SMC37507.1NADPH:quinone reductase. (325 aa)
SMC37337.1Uncharacterized protein YpbB. (337 aa)
scpBCondensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (181 aa)
SMC37119.1Pyruvate kinase; Belongs to the pyruvate kinase family. (587 aa)
SMC36995.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (477 aa)
SMC36514.1Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (148 aa)
SMC36061.1Acyl dehydratase. (170 aa)
SMC34816.1Transcriptional regulator, RpiR family. (247 aa)
SMC34508.1Glycolate oxidase. (444 aa)
SMC34330.16-phosphogluconolactonase. (342 aa)
SMC34323.1NADP-dependent alcohol dehydrogenase. (393 aa)
SMC34298.1Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
SMC33540.1Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
SMC33487.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (874 aa)
SMC33414.1PTS system, fructose-specific IIC component. (648 aa)
SMC33060.1Amidase. (489 aa)
SMC33012.1Amidase. (364 aa)
SMC32968.1F420-0:Gamma-glutamyl ligase. (396 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
SMC31023.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
SMC31007.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
SMC30957.1NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. (451 aa)
SMC30949.1S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
SMC30946.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (276 aa)
SMC30919.1Phosphotransferase system, fructose-specific IIC component. (340 aa)
SMC30887.1L-glutamine synthetase. (445 aa)
SMC30785.1Aminopeptidase. (413 aa)
SMC30780.1Flavodoxin, short chain. (148 aa)
SMC30768.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
SMC30751.1Uncharacterized NAD(P)/FAD-binding protein YdhS. (500 aa)
SMC30701.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (347 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa)
SMC30599.1Pyruvate dehydrogenase E1 component beta subunit. (323 aa)
SMC30597.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (533 aa)
SMC30596.1Dihydrolipoamide dehydrogenase. (470 aa)
SMC30583.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1145 aa)
SMC30551.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (467 aa)
SMC30461.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
SMC30398.1Putative hydrolase of the HAD superfamily. (232 aa)
SMC30305.1ACT domain-containing protein. (87 aa)
Your Current Organism:
Aerococcus suis
NCBI taxonomy Id: 371602
Other names: Aerococcus suis Vela et al. 2007 emend. Tohno et al. 2014, CCUG 52530, CECT 7139, DSM 21500, JCM 18035
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