48 items (Patagioenas fasciata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APP	Amyloid beta A4 protein. (746 aa)
	AV530_016122	Uncharacterized protein. (370 aa)
	FCHO2	F-BAR domain only protein 2. (1001 aa)
	AV530_007933	Uncharacterized protein. (323 aa)
	VLDLR	Very low-density lipoprotein receptor. (861 aa)
	HSPD1	Heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa)
	AV530_003867	Phosphatidylinositol-binding clathrin assembly protein. (674 aa)
	SORT1-2	Sortilin. (416 aa)
	EPN3	Epsin-3 isoform B. (644 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
	CLTB	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (254 aa)
	AAK1	AP2-associated protein kinase 1 isoform B. (1045 aa)
	EPS15L1	Epidermal growth factor receptor substrate 15-like 1 isoform A. (927 aa)
	FCHO1	F-BAR domain only protein 1. (794 aa)
	OCRL	Inositol polyphosphate 5-phosphatase OCRL-1 isoform A. (861 aa)
	SLC18A3	Vesicular acetylcholine transporter. (476 aa)
	AV530_015621	Phosphatidylinositide phosphatase SAC2. (1122 aa)
	AV530_004778	Uncharacterized protein. (82 aa)
	AV530_012188	Stonin-1; Belongs to the Stoned B family. (740 aa)
	AV530_010254	Epidermal growth factor receptor substrate 15. (917 aa)
	DNM1L	Dynamin-1-like protein isoform B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (287 aa)
	SH3BP4	SH3 domain-binding protein 4. (964 aa)
	LRP1B	Low-density lipoprotein receptor-related protein 1B isoform E. (4461 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (244 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (218 aa)
	AP2M1	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (433 aa)
	AV530_017928	muHD domain-containing protein. (241 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
	AV530_007899	MHD domain-containing protein. (79 aa)
	SGIP1	SH3-containing GRB2-like protein 3-interacting protein 1 isoform C. (778 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (966 aa)
	HIP1R	Huntingtin-interacting protein 1-related protein. (1061 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	PICALM	Phosphatidylinositol-binding clathrin assembly protein isoform C. (627 aa)
	RAB35	Ras-related protein Rab-35. (201 aa)
	ITSN2	Intersectin-2 isoform A. (1771 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (951 aa)
	MYO6	Unconventional myosin-VI isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1263 aa)
	SNAP91	Clathrin coat assembly protein AP180. (784 aa)
	REPS1	RalBP1-associated Eps domain-containing protein 1 isoform B. (797 aa)
	AV530_010197	Uncharacterized protein. (313 aa)
	AV530_017526	Uncharacterized protein. (1332 aa)
	AV530_017527	Uncharacterized protein. (1561 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (178 aa)
	AV530_012174	Uncharacterized protein. (90 aa)
	FNBP1	Formin-binding protein 1 isoform B. (613 aa)
	ITSN1	Intersectin-1 isoform B. (1580 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	AP2A2	A0A1V4KSP8	A0A1V4JNI5	AP2-associated protein kinase 1 isoform B.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.515
AAK1	AP2M1	A0A1V4KSP8	A0A1V4K3I8	AP2-associated protein kinase 1 isoform B.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.898
AAK1	AV530_003867	A0A1V4KSP8	A0A1V4KZ61	AP2-associated protein kinase 1 isoform B.	Phosphatidylinositol-binding clathrin assembly protein.	0.791
AAK1	AV530_004778	A0A1V4KSP8	A0A1V4KHD5	AP2-associated protein kinase 1 isoform B.	Uncharacterized protein.	0.482
AAK1	AV530_007899	A0A1V4KSP8	A0A1V4JZL4	AP2-associated protein kinase 1 isoform B.	MHD domain-containing protein.	0.482
AAK1	AV530_010254	A0A1V4KSP8	A0A1V4KD31	AP2-associated protein kinase 1 isoform B.	Epidermal growth factor receptor substrate 15.	0.864
AAK1	AV530_012174	A0A1V4KSP8	A0A1V4J8S0	AP2-associated protein kinase 1 isoform B.	Uncharacterized protein.	0.482
AAK1	AV530_017928	A0A1V4KSP8	A0A1V4K350	AP2-associated protein kinase 1 isoform B.	muHD domain-containing protein.	0.482
AAK1	CLTA	A0A1V4KSP8	A0A1V4K5H3	AP2-associated protein kinase 1 isoform B.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.614
AAK1	CLTB	A0A1V4KSP8	A0A1V4KUE5	AP2-associated protein kinase 1 isoform B.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.614
AAK1	CLTC	A0A1V4KSP8	A0A1V4K298	AP2-associated protein kinase 1 isoform B.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.688
AAK1	CLTCL1	A0A1V4KSP8	A0A1V4JRJ5	AP2-associated protein kinase 1 isoform B.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.688
AAK1	DNM1L	A0A1V4KSP8	A0A1V4K9P6	AP2-associated protein kinase 1 isoform B.	Dynamin-1-like protein isoform B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.569
AAK1	EPN3	A0A1V4KSP8	A0A1V4KVX2	AP2-associated protein kinase 1 isoform B.	Epsin-3 isoform B.	0.614
AAK1	EPS15L1	A0A1V4KSP8	A0A1V4KQL6	AP2-associated protein kinase 1 isoform B.	Epidermal growth factor receptor substrate 15-like 1 isoform A.	0.864
AAK1	FCHO1	A0A1V4KSP8	A0A1V4KQ94	AP2-associated protein kinase 1 isoform B.	F-BAR domain only protein 1.	0.482
AAK1	FCHO2	A0A1V4KSP8	A0A1V4L1C9	AP2-associated protein kinase 1 isoform B.	F-BAR domain only protein 2.	0.482
AAK1	HIP1R	A0A1V4KSP8	A0A1V4JSN5	AP2-associated protein kinase 1 isoform B.	Huntingtin-interacting protein 1-related protein.	0.711
AAK1	ITSN1	A0A1V4KSP8	A0A1V4J2U0	AP2-associated protein kinase 1 isoform B.	Intersectin-1 isoform B.	0.523
AAK1	ITSN2	A0A1V4KSP8	A0A1V4JNM7	AP2-associated protein kinase 1 isoform B.	Intersectin-2 isoform A.	0.710