STRINGSTRING
SNAP25 SNAP25 AV530_014201 AV530_014201 GAK GAK SCARF2 SCARF2 ITSN1 ITSN1 DRD3 DRD3 RABEPK RABEPK DNM1 DNM1 AV530_012174 AV530_012174 CAV2 CAV2 RAB31 RAB31 CACNG2 CACNG2 MICALL1 MICALL1 CAV1 CAV1 SCYL2 SCYL2 LDLRAP1 LDLRAP1 AP4E1 AP4E1 LRRTM1 LRRTM1 AV530_010197 AV530_010197 AV530_017091 AV530_017091 FCER1G FCER1G PPT1 PPT1 CNR2 CNR2 CAV3 CAV3 DLL1 DLL1 SNX9 SNX9 EZR EZR REPS1 REPS1 SNAP91 SNAP91 WASF1 WASF1 LMBRD1 LMBRD1 CNR1 CNR1 AP2A2 AP2A2 ITSN2 ITSN2 ADRBK1 ADRBK1 TPCN2 TPCN2 RAMP2 RAMP2 PICALM PICALM CLTCL1 CLTCL1 ADRBK2 ADRBK2 AV530_001387 AV530_001387 HIP1R HIP1R CXCL8 CXCL8 RAMP3 RAMP3 DNAJC6 DNAJC6 SGIP1 SGIP1 DNM3 DNM3 AV530_007675 AV530_007675 FNBP1L FNBP1L AV530_007899 AV530_007899 CD36 CD36 MAGI2 MAGI2 CLTC CLTC SCARF1 SCARF1 RABGEF1 RABGEF1 AV530_017928 AV530_017928 AP2M1 AP2M1 SAG SAG CLTA CLTA MARCO MARCO ITGA4 ITGA4 CALCRL CALCRL CD9 CD9 LRP6 LRP6 ACKR3 ACKR3 AV530_014317 AV530_014317 MRC1 MRC1 AV530_014318 AV530_014318 AMN AMN TMEM108 TMEM108 DNAJC13 DNAJC13 AV530_010210 AV530_010210 AV530_010306 AV530_010306 LDLRAD3 LDLRAD3 AV530_013183 AV530_013183 AV530_009187 AV530_009187 AV530_004047 AV530_004047 AV530_004778 AV530_004778 AV530_015621 AV530_015621 AV530_010652 AV530_010652 AV530_007054 AV530_007054 AV530_007053 AV530_007053 AV530_007143 AV530_007143 TFRC TFRC SNX1 SNX1 AV530_011443 AV530_011443 AV530_011445 AV530_011445 FCHO1 FCHO1 AV530_009550 AV530_009550 AV530_009577 AV530_009577 SIGLEC1 SIGLEC1 GRIA1 GRIA1 CLTB CLTB CD14 CD14 CACNG4 CACNG4 CACNG5 CACNG5 AV530_008413 AV530_008413 ARR3 ARR3 AV530_003867 AV530_003867 PIKFYVE PIKFYVE AV530_017859 AV530_017859 SCARB2 SCARB2 FCHO2 FCHO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
AV530_014201Uncharacterized protein. (84 aa)
GAKCyclin-G-associated kinase. (1315 aa)
SCARF2Scavenger receptor class F member 2. (927 aa)
ITSN1Intersectin-1 isoform B. (1580 aa)
DRD3D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RABEPKRab9 effector protein with kelch motifs. (190 aa)
DNM1Dynamin-1 isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (861 aa)
AV530_012174Uncharacterized protein. (90 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (114 aa)
RAB31Ras-related protein Rab-31 isoform B. (263 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
MICALL1MICAL-like protein 1. (779 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SCYL2SCY1-like protein 2. (996 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1 isoform B. (307 aa)
AP4E1AP-4 complex subunit epsilon-1. (1150 aa)
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1. (455 aa)
AV530_010197Uncharacterized protein. (313 aa)
AV530_017091ENTH domain-containing protein. (113 aa)
FCER1GFc of IgE, high affinity I, receptor for gamma polypeptide. (89 aa)
PPT1Palmitoyl-protein thioesterase 1. (301 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (345 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (727 aa)
SNX9Sorting nexin. (600 aa)
EZREzrin. (586 aa)
REPS1RalBP1-associated Eps domain-containing protein 1 isoform B. (797 aa)
SNAP91Clathrin coat assembly protein AP180. (784 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (608 aa)
LMBRD1Putative lysosomal cobalamin transporter. (539 aa)
CNR1Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (503 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (951 aa)
ITSN2Intersectin-2 isoform A. (1771 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (638 aa)
TPCN2Two pore calcium channel protein 2. (750 aa)
RAMP2Receptor activity-modifying protein 2. (174 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform C. (627 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
AV530_001387Uncharacterized protein. (153 aa)
HIP1RHuntingtin-interacting protein 1-related protein. (1061 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
RAMP3Receptor activity-modifying protein 3. (156 aa)
DNAJC6Putative tyrosine-protein phosphatase auxilin. (919 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1 isoform C. (778 aa)
DNM3Dynamin-3 isoform B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (865 aa)
AV530_007675Uncharacterized protein. (1735 aa)
FNBP1LFormin-binding protein 1-like. (547 aa)
AV530_007899MHD domain-containing protein. (79 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (449 aa)
MAGI2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform B. (1542 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
SCARF1Scavenger receptor class F member 1. (873 aa)
RABGEF1Rab5 GDP/GTP exchange factor isoform B. (753 aa)
AV530_017928muHD domain-containing protein. (241 aa)
AP2M1AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (433 aa)
SAGS-arrestin. (334 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (244 aa)
MARCOMacrophage receptor MARCO. (481 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1024 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor isoform B; Belongs to the G-protein coupled receptor 2 family. (836 aa)
CD9Tetraspanin. (224 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1596 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (287 aa)
AV530_014317C-type lectin domain-containing protein. (238 aa)
MRC1Macrophage mannose receptor 1 isoform A. (1460 aa)
AV530_014318Macrophage mannose receptor 1. (1428 aa)
AMNProtein amnionless. (478 aa)
TMEM108Transmembrane protein 108 isoform A. (476 aa)
DNAJC13DnaJ-like protein subfamily C member 13. (2272 aa)
AV530_010210Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (282 aa)
AV530_010306Uncharacterized protein. (78 aa)
LDLRAD3Low-density lipoprotein receptor class A domain-containing protein 3. (292 aa)
AV530_013183Beta-arrestin-1. (336 aa)
AV530_009187Uncharacterized protein. (100 aa)
AV530_004047SH3 domain-containing protein. (102 aa)
AV530_004778Uncharacterized protein. (82 aa)
AV530_015621Phosphatidylinositide phosphatase SAC2. (1122 aa)
AV530_010652Uncharacterized protein. (162 aa)
AV530_007054Uncharacterized protein. (87 aa)
AV530_007053Uncharacterized protein. (80 aa)
AV530_007143ANTH domain-containing protein. (119 aa)
TFRCTransferrin receptor protein 1. (901 aa)
SNX1Sorting nexin-1. (484 aa)
AV530_011443Uncharacterized protein. (892 aa)
AV530_011445Uncharacterized protein. (519 aa)
FCHO1F-BAR domain only protein 1. (794 aa)
AV530_009550ADF-H domain-containing protein. (204 aa)
AV530_009577Ig-like domain-containing protein. (116 aa)
SIGLEC1Sialoadhesin. (726 aa)
GRIA1Glutamate receptor 1 isoform B. (944 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (254 aa)
CD14Monocyte differentiation antigen CD14. (529 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (345 aa)
AV530_008413Uncharacterized protein. (724 aa)
ARR3Arrestin-C. (352 aa)
AV530_003867Phosphatidylinositol-binding clathrin assembly protein. (674 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform B. (2118 aa)
AV530_017859Uncharacterized protein. (83 aa)
SCARB2Lysosome membrane protein 2 isoform B; Belongs to the CD36 family. (503 aa)
FCHO2F-BAR domain only protein 2. (1001 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.