(13 nodes) Regulation of cardiac muscle cell proliferation network (Patagioenas fasciata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	TBX20	T-box transcription factor TBX20. (402 aa)
	KCNK2	Potassium channel subfamily K member 2 isoform B; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (439 aa)
	TBX5	T-box transcription factor TBX5. (529 aa)
	VGLL4	Transcription cofactor vestigial-like protein 4. (293 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	MAPK11	Mitogen-activated protein kinase. (335 aa)
	ZFPM2	Zinc finger protein ZFPM2. (1151 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (620 aa)
	NKX2-5	Homeobox protein Nkx-2.5. (299 aa)
	NOG	Noggin; Belongs to the noggin family. (223 aa)
	MAPK14	Mitogen-activated protein kinase. (380 aa)
	AV530_007120	SARAH domain-containing protein. (224 aa)
	SAV1	Salvador-like protein 1. (167 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAPK11	MAPK14	A0A1V4K363	A0A1V4KWS3	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.813
MAPK11	TGFBR1	A0A1V4K363	A0A1V4JV94	Mitogen-activated protein kinase.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.480
MAPK11	TP73	A0A1V4K363	A0A1V4KNI0	Mitogen-activated protein kinase.	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.647
MAPK14	MAPK11	A0A1V4KWS3	A0A1V4K363	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.813
MAPK14	TGFBR1	A0A1V4KWS3	A0A1V4JV94	Mitogen-activated protein kinase.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.480
MAPK14	TP73	A0A1V4KWS3	A0A1V4KNI0	Mitogen-activated protein kinase.	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.647
NKX2-5	TBX20	A0A1V4KUE4	A0A1V4J6E3	Homeobox protein Nkx-2.5.	T-box transcription factor TBX20.	0.705
NKX2-5	TBX5	A0A1V4KUE4	A0A1V4JR48	Homeobox protein Nkx-2.5.	T-box transcription factor TBX5.	0.945
TBX20	NKX2-5	A0A1V4J6E3	A0A1V4KUE4	T-box transcription factor TBX20.	Homeobox protein Nkx-2.5.	0.705
TBX5	NKX2-5	A0A1V4JR48	A0A1V4KUE4	T-box transcription factor TBX5.	Homeobox protein Nkx-2.5.	0.945
TGFBR1	MAPK11	A0A1V4JV94	A0A1V4K363	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mitogen-activated protein kinase.	0.480
TGFBR1	MAPK14	A0A1V4JV94	A0A1V4KWS3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mitogen-activated protein kinase.	0.480
TP73	MAPK11	A0A1V4KNI0	A0A1V4K363	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Mitogen-activated protein kinase.	0.647
TP73	MAPK14	A0A1V4KNI0	A0A1V4KWS3	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	Mitogen-activated protein kinase.	0.647