(30 nodes) Positive regulation of transcription initiation from RNA polymerase II promoter network (Patagioenas fasciata)

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Your Input:
	AV530_009538	TAF domain-containing protein. (86 aa)
	AV530_014958	Transcription initiation factor TFIID subunit 4. (704 aa)
	TAF3	Transcription initiation factor TFIID subunit 3. (677 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1567 aa)
	MED24	Mediator of RNA polymerase II transcription subunit 24. (1002 aa)
	AV530_019721	Uncharacterized protein. (198 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	MED14	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1447 aa)
	TAF13	Transcription initiation factor TFIID subunit 13. (124 aa)
	AV530_007086	PC4 domain-containing protein. (80 aa)
	TAF12	Transcription initiation factor TFIID subunit 12. (161 aa)
	TBP	TATA-box-binding protein. (304 aa)
	MED4	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (310 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1554 aa)
	DHX36	ATP-dependent RNA helicase DHX36. (997 aa)
	AV530_006696	Activated RNA polymerase II transcriptional coactivator p15-like. (126 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (831 aa)
	NKX2-5	Homeobox protein Nkx-2.5. (299 aa)
	TAF8	Transcription initiation factor TFIID subunit 8. (312 aa)
	AV530_016434	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (603 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (643 aa)
	SUB1	Activated RNA polymerase II transcriptional coactivator p15. (142 aa)
	HNF1B	Hepatocyte nuclear factor 1-beta isoform A. (436 aa)
	MED13	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2179 aa)
	TAF4	Transcription initiation factor TFIID subunit 4. (1164 aa)
	MED30	Mediator of RNA polymerase II transcription subunit 30. (169 aa)
	TAF4B	Transcription initiation factor TFIID subunit 4B isoform D. (874 aa)
	GTF2A1	Transcription initiation factor IIA subunit 1. (368 aa)
	SRF	Serum response factor isoform A. (421 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (384 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AV530_009538	AV530_014958	A0A1V4K9S0	A0A1V4K0F2	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 4.	0.979
AV530_009538	AV530_016434	A0A1V4K9S0	A0A1V4KZ97	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.597
AV530_009538	GTF2A1	A0A1V4K9S0	A0A1V4KB19	TAF domain-containing protein.	Transcription initiation factor IIA subunit 1.	0.923
AV530_009538	GTF2A2	A0A1V4K9S0	A0A1V4JDP1	TAF domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.882
AV530_009538	MED1	A0A1V4K9S0	A0A1V4JQK6	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.597
AV530_009538	MED14	A0A1V4K9S0	A0A1V4JCI2	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.660
AV530_009538	MED16	A0A1V4K9S0	A0A1V4KQ59	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.660
AV530_009538	MED17	A0A1V4K9S0	A0A1V4L117	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.713
AV530_009538	MED24	A0A1V4K9S0	A0A1V4JQI4	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 24.	0.660
AV530_009538	MED30	A0A1V4K9S0	A0A1V4KIY0	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 30.	0.660
AV530_009538	MED4	A0A1V4K9S0	A0A1V4J4F2	TAF domain-containing protein.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.693
AV530_009538	TAF12	A0A1V4K9S0	A0A1V4JI46	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 12.	0.999
AV530_009538	TAF13	A0A1V4K9S0	A0A1V4J379	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 13.	0.999
AV530_009538	TAF3	A0A1V4K9S0	A0A1V4JZ32	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 3.	0.985
AV530_009538	TAF4	A0A1V4K9S0	A0A1V4KK83	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 4.	0.979
AV530_009538	TAF4B	A0A1V4K9S0	A0A1V4KG81	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 4B isoform D.	0.965
AV530_009538	TAF8	A0A1V4K9S0	A0A1V4KWU5	TAF domain-containing protein.	Transcription initiation factor TFIID subunit 8.	0.999
AV530_009538	TBP	A0A1V4K9S0	A0A1V4JKS0	TAF domain-containing protein.	TATA-box-binding protein.	0.980
AV530_014958	AV530_009538	A0A1V4K0F2	A0A1V4K9S0	Transcription initiation factor TFIID subunit 4.	TAF domain-containing protein.	0.979
AV530_014958	AV530_016434	A0A1V4K0F2	A0A1V4KZ97	Transcription initiation factor TFIID subunit 4.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.575