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| | COPB2 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (913 aa) |
| | TOM1 | Target of Myb protein 1 isoform B; Belongs to the TOM1 family. (514 aa) |
| | TIMM9 | Mitochondrial import inner membrane translocase subunit Tim9. (89 aa) |
| | SNX5 | Sorting nexin; Involved in several stages of intracellular trafficking. (397 aa) |
| | VPS28 | Vacuolar sorting-associated protein 28-like protein; Belongs to the VPS28 family. (864 aa) |
| | SEC23B | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa) |
| | AV530_020140 | Angiopoietin-related protein 1. (382 aa) |
| | SNX6 | Sorting nexin; Involved in several stages of intracellular trafficking. (407 aa) |
| | TRAM1 | Translocating chain-associated membrane protein; Belongs to the TRAM family. (374 aa) |
| | ENY2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (90 aa) |
| | SEC23A | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (732 aa) |
| | AP3M2 | AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (443 aa) |
| | TIMM23 | Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (206 aa) |
| | SEC24C | Protein transport protein Sec24C isoform A. (1085 aa) |
| | AP3M1 | AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (425 aa) |
| | SAR1A | GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | SYS1 | Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (156 aa) |
| | AV530_001655 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa) |
| | KPNA4 | Importin subunit alpha; Belongs to the importin alpha family. (521 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (504 aa) |
| | LIN7A | Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (218 aa) |
| | AP3B2 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1099 aa) |
| | VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa) |
| | GOSR2 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (229 aa) |
| | COPE | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (306 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa) |
| | AP1M1 | AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (423 aa) |
| | KDELR2 | ER lumen protein-retaining receptor. (212 aa) |
| | BBS7 | Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (716 aa) |
| | SEC24B | Protein transport protein Sec24B isoform B. (1235 aa) |
| | VPS29 | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa) |
| | AP1B1 | AP complex subunit beta. (1027 aa) |
| | AP3D1 | AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1162 aa) |
| | KPNA7 | Importin subunit alpha; Belongs to the importin alpha family. (516 aa) |
| | TOM1L2 | TOM1-like protein 2 isoform A; Belongs to the TOM1 family. (531 aa) |
| | SAR1B | GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (651 aa) |
| | TOM1L1 | TOM1-like protein 1; Belongs to the TOM1 family. (471 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (732 aa) |
| | SEC24A | Protein transport protein Sec24A. (1102 aa) |
| | TIMM17A | Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (166 aa) |
| | AP4B1 | AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | TIMM8A | Mitochondrial import inner membrane translocase subunit Tim8 A; Belongs to the small Tim family. (94 aa) |
| | SDAD1 | Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (691 aa) |
| | ATG4A | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (412 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1100 aa) |
| | COPA | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa) |
| | VPS37B | Vacuolar protein sorting-associated protein 37B. (286 aa) |
| | COPZ2 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (198 aa) |
| | AV530_015432 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (372 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | TIMM10 | Mitochondrial import inner membrane translocase subunit Tim10. (66 aa) |
| | VPS37C | Vacuolar protein sorting-associated protein 37C. (178 aa) |
| | LIN7C | Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa) |
| | COPB1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa) |
| | TSG101 | Tumor susceptibility 101 protein. (391 aa) |
| | AP2A2 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (951 aa) |
| | KPNA5 | Importin subunit alpha; Belongs to the importin alpha family. (539 aa) |
| | AP3S1 | AP-3 complex subunit sigma-1. (193 aa) |
| | SFT2D1 | Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (213 aa) |
| | SEC13 | SEC13-like protein; Belongs to the WD repeat SEC13 family. (306 aa) |
| | SEC61A1 | Protein transport protein Sec61 subunit alpha. (476 aa) |
| | COPG1 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa) |
| | HNRNPA3 | Heterogeneous nuclear ribonucleoprotein A3 isoform C. (693 aa) |
| | VPS37A | Vacuolar protein sorting-associated protein 37A. (391 aa) |
| | AP4E1 | AP-4 complex subunit epsilon-1. (1150 aa) |
| | AV530_019446 | AP-3 complex subunit sigma-2. (254 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (178 aa) |
| | KPNA1 | Importin subunit alpha; Belongs to the importin alpha family. (550 aa) |
| | AV530_018610 | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (135 aa) |
| | KDELR3 | ER lumen protein-retaining receptor. (214 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (919 aa) |
| | SEH1L | Nucleoporin SEH1; Belongs to the WD repeat SEC13 family. (326 aa) |
| | ARCN1 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (487 aa) |
| | SEC61B | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (927 aa) |
| | TIMM13 | Mitochondrial import inner membrane translocase subunit Tim13 isoform A; Belongs to the small Tim family. (88 aa) |
| | SEC16A | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1580 aa) |
| | AV530_000352 | Clat_adaptor_s domain-containing protein. (125 aa) |
| | KPNA3 | Importin subunit alpha; Belongs to the importin alpha family. (540 aa) |
| | COG6 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (647 aa) |
| | SFT2D2 | Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (160 aa) |
| | ATG3 | Autophagy-related protein 3. (338 aa) |
| | SEC61A2 | Protein transport protein Sec61 subunit alpha. (476 aa) |
| | ATG4C | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (429 aa) |
| | SEC16B | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1167 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (925 aa) |
| | COPG2 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (871 aa) |
| | TIMM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (213 aa) |
| | SEC24D | Protein transport protein Sec24D. (1034 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | PHLPP2 | PH domain leucine-rich repeat-containing protein phosphatase 2. (2143 aa) |
| | GOSR1 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (248 aa) |
| | AP2B1 | AP complex subunit beta. (951 aa) |
| | AV530_015248 | Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family. (535 aa) |
| | AP2M1 | AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (433 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (218 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (807 aa) |
