44 items (Patagioenas fasciata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1176 aa)
	SOS1	Son of sevenless-like protein 1. (1345 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (178 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform B. (677 aa)
	AV530_012955	Arf-GAP with dual PH domain-containing protein 1. (379 aa)
	AV530_009181	PID domain-containing protein. (305 aa)
	NRG4	Pro-neuregulin-4, membrane-bound. (118 aa)
	NEDD4	E3 ubiquitin-protein ligase. (902 aa)
	KRAS	GTPase KRas isoform A. (192 aa)
	MXD4	Max dimerization protein 4. (205 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (430 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (457 aa)
	AV530_011470	Uncharacterized protein. (92 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (587 aa)
	HRAS	GTPase HRas. (184 aa)
	AV530_001374	Signal transducer and activator of transcription. (787 aa)
	AV530_019865	Gamma-secretase subunit Aph-1b. (256 aa)
	AV530_008992	HECT domain-containing protein. (138 aa)
	EREG	Proepiregulin. (153 aa)
	EGF	Pro-epidermal growth factor. (1254 aa)
	SHC1	SHC-transforming protein 1. (323 aa)
	WWOX	WW domain-containing oxidoreductase. (353 aa)
	UBC	Polyubiquitin-C isoform A. (365 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1208 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
	AV530_009431	Uncharacterized protein. (92 aa)
	AV530_004803	Uncharacterized protein. (541 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
	AV530_012204	Uncharacterized protein. (153 aa)
	WWP1	E3 ubiquitin-protein ligase. (923 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform isoform B. (457 aa)
	SRC	Tyrosine-protein kinase. (585 aa)
	APH1A	Gamma-secretase subunit APH-1A. (248 aa)
	ADAP1	Arf-GAP with dual PH domain-containing protein 1. (375 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (272 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform isoform A. (734 aa)
	ADAP2	Arf-GAP with dual PH domain-containing protein 2. (457 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CSDE1	Cold shock domain-containing protein E1. (1129 aa)
	NRAS	GTPase NRas. (189 aa)
	AV530_013970	HECT domain-containing protein. (156 aa)
	AV530_003606	Fibronectin type-III domain-containing protein 3a-like. (1166 aa)
	BTC	Probetacellulin isoform A. (191 aa)
	NCSTN	Nicastrin. (703 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH1A	NCSTN	A0A1V4KML5	A0A1V4L180	Gamma-secretase subunit APH-1A.	Nicastrin.	0.948
APH1A	PSEN1	A0A1V4KML5	A0A1V4KEW2	Gamma-secretase subunit APH-1A.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.932
APH1A	PSEN2	A0A1V4KML5	A0A1V4JJ63	Gamma-secretase subunit APH-1A.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.924
AV530_001374	ESR1	A0A1V4JQT0	A0A1V4JLJ4	Signal transducer and activator of transcription.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.445
AV530_001374	GRB2	A0A1V4JQT0	A0A1V4KW39	Signal transducer and activator of transcription.	Growth factor receptor-bound protein 2.	0.487
AV530_001374	SRC	A0A1V4JQT0	A0A1V4KL44	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.748
AV530_001374	UBC	A0A1V4JQT0	A0A1V4K2F8	Signal transducer and activator of transcription.	Polyubiquitin-C isoform A.	0.415
AV530_003606	RPS27A	A0A1V4KY83	A0A1V4IG00	Fibronectin type-III domain-containing protein 3a-like.	Ubiquitin-40S ribosomal protein S27a.	0.431
AV530_004803	AV530_012204	A0A1V4KDZ8	A0A1V4KEX9	Uncharacterized protein.	Uncharacterized protein.	0.860
AV530_004803	AV530_013970	A0A1V4KDZ8	A0A1V4KY04	Uncharacterized protein.	HECT domain-containing protein.	0.853
AV530_004803	GRB2	A0A1V4KDZ8	A0A1V4KW39	Uncharacterized protein.	Growth factor receptor-bound protein 2.	0.597
AV530_004803	NEDD4	A0A1V4KDZ8	A0A1V4JDH5	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.763
AV530_004803	RPS27A	A0A1V4KDZ8	A0A1V4IG00	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a.	0.881
AV530_004803	UBC	A0A1V4KDZ8	A0A1V4K2F8	Uncharacterized protein.	Polyubiquitin-C isoform A.	0.855
AV530_004803	WWP1	A0A1V4KDZ8	A0A1V4KIF5	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.874
AV530_008992	AV530_012204	A0A1V4JV29	A0A1V4KEX9	HECT domain-containing protein.	Uncharacterized protein.	0.893
AV530_008992	AV530_013970	A0A1V4JV29	A0A1V4KY04	HECT domain-containing protein.	HECT domain-containing protein.	0.925
AV530_008992	GRB2	A0A1V4JV29	A0A1V4KW39	HECT domain-containing protein.	Growth factor receptor-bound protein 2.	0.597
AV530_008992	NEDD4	A0A1V4JV29	A0A1V4JDH5	HECT domain-containing protein.	E3 ubiquitin-protein ligase.	0.763
AV530_008992	RPS27A	A0A1V4JV29	A0A1V4IG00	HECT domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.881