STRINGSTRING
CD14 CD14 MAP2K6 MAP2K6 MAPK14 MAPK14 MAPKAPK2 MAPKAPK2 LRRC71 LRRC71 ITGB2 ITGB2 LRRC14 LRRC14 S100Z S100Z CREB1 CREB1 FADD FADD CTSB CTSB VWC2 VWC2 FBXW11 FBXW11 AV530_016196 AV530_016196 LY86 LY86 AV530_004017 AV530_004017 DNM3 DNM3 AV530_007725 AV530_007725 AV530_007724 AV530_007724 AV530_007742 AV530_007742 AV530_015540 AV530_015540 S100A1 S100A1 CD36 CD36 PLCG2 PLCG2 ITGAE ITGAE UBC UBC SARM1 SARM1 MAPK11 MAPK11 AV530_003365 AV530_003365 LRRC45 LRRC45 PTPN4 PTPN4 TANK TANK UBE2D1-2 UBE2D1-2 AV530_002466 AV530_002466 AV530_002465 AV530_002465 ATF2 ATF2 AV530_010741 AV530_010741 AV530_010740 AV530_010740 DUSP7 DUSP7 MAPKAPK3 MAPKAPK3 HSP90B1 HSP90B1 AV530_011476 AV530_011476 AV530_011478 AV530_011478 TRAF3 TRAF3 PPP4R4 PPP4R4 RPS6KA5 RPS6KA5 LGMN LGMN AV530_014682 AV530_014682 HMGB1 HMGB1 VPS28 VPS28 CREB5 CREB5 NKIRAS1 NKIRAS1 AV530_014524 AV530_014524 NOD1 NOD1 AV530_010210 AV530_010210 CTSL CTSL DFNA5 DFNA5 AV530_004854 AV530_004854 FOS FOS LRRC74A LRRC74A USP14 USP14 TRAF6 TRAF6 CUL1 CUL1 AV530_002806 AV530_002806 MAPK10 MAPK10 AV530_007822 AV530_007822 UBE2D3 UBE2D3 NFKB1 NFKB1 PTPN11 PTPN11 AV530_015360 AV530_015360 FGG FGG TLR2B TLR2B RPS27A RPS27A AV530_000672 AV530_000672 MAP2K4 MAP2K4 DNM1 DNM1 TLR4 TLR4 PPP4R1 PPP4R1 TIRAP TIRAP BIRC2 BIRC2 TBK1 TBK1 IKBIP IKBIP TLR7 TLR7 RPS6KA3 RPS6KA3 ATF1 ATF1 TAB3 TAB3 LY96 LY96 IKBKB IKBKB MAPK8 MAPK8 NFKB2 NFKB2 AV530_015988 AV530_015988 AV530_007050 AV530_007050 BIRC7 BIRC7 AV530_018033 AV530_018033 BPI BPI UBE2V1 UBE2V1 AV530_015989 AV530_015989 MAP3K8 MAP3K8 LRRC34 LRRC34 LRRC31 LRRC31 AV530_009231 AV530_009231 AV530_009252 AV530_009252 AV530_009234 AV530_009234 EEA1 EEA1 DUSP6 DUSP6 AV530_017334 AV530_017334 TLR3 TLR3 IRAK2 IRAK2 TLR5 TLR5 TRAF5 TRAF5 UNC93A UNC93A FOSL2 FOSL2 RPS6KA2 RPS6KA2 TAB2 TAB2 MAP3K7 MAP3K7 APOB APOB MAPK1 MAPK1 DUSP3 DUSP3 NKIRAS2 NKIRAS2 PPP2R1A PPP2R1A N4BP1 N4BP1 MAPK15 MAPK15 AV530_013995 AV530_013995 AV530_011288 AV530_011288 CTSK CTSK TRAF2 TRAF2 KXD1 KXD1 MAP3K1 MAP3K1 MAP2K3 MAP2K3 AV530_001035 AV530_001035 VRK3 VRK3 AV530_001177 AV530_001177 MAPK9 MAPK9 SKP1 SKP1 UBE2D2 UBE2D2 ECSIT ECSIT FNBP4 FNBP4 AV530_013981 AV530_013981 IRF7 IRF7 AV530_013269 AV530_013269 UNC93B1 UNC93B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD14Monocyte differentiation antigen CD14. (529 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
MAPK14Mitogen-activated protein kinase. (380 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
LRRC71Leucine-rich repeat-containing protein 71. (240 aa)
ITGB2Integrin beta. (787 aa)
LRRC14Leucine-rich repeat-containing protein 14. (973 aa)
S100ZProtein S100; Belongs to the S-100 family. (106 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (303 aa)
FADDFAS-associated death domain protein. (139 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (383 aa)
VWC2Brorin. (331 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform A. (513 aa)
AV530_016196LisH domain and HEAT repeat-containing KIAA1468-like protein. (1124 aa)
LY86Lymphocyte antigen 86. (161 aa)
AV530_004017Caspase-8; Belongs to the peptidase C14A family. (490 aa)
DNM3Dynamin-3 isoform B; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (865 aa)
AV530_007725Vitellogenin-2-like. (1534 aa)
AV530_007724Vitellogenin-2-like. (1586 aa)
AV530_007742Vitellogenin-1. (1703 aa)
AV530_015540Uncharacterized protein. (113 aa)
S100A1Protein S100; Belongs to the S-100 family. (145 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (449 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1216 aa)
ITGAEIntegrin alpha-E; Belongs to the integrin alpha chain family. (1234 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (716 aa)
MAPK11Mitogen-activated protein kinase. (335 aa)
AV530_003365Uncharacterized protein. (154 aa)
LRRC45Leucine-rich repeat-containing protein 45. (848 aa)
PTPN4Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (962 aa)
TANKTRAF family member-associated NF-kappa-B activator. (482 aa)
UBE2D1-2Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
AV530_002466SAM domain-containing protein. (436 aa)
AV530_002465Mitogen-activated protein kinase kinase kinase MLT. (450 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform B. (569 aa)
AV530_010741BPI fold-containing family C protein. (443 aa)
AV530_010740BPI2 domain-containing protein. (197 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (409 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform B; Belongs to the protein kinase superfamily. (387 aa)
HSP90B1Endoplasmin. (795 aa)
AV530_011476TPR_REGION domain-containing protein. (211 aa)
AV530_011478Uncharacterized protein. (190 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform B. (870 aa)
RPS6KA5Ribosomal protein S6 kinase. (789 aa)
LGMNLegumain. (412 aa)
AV530_014682Canopy-like protein 3. (254 aa)
HMGB1High mobility group protein B1. (215 aa)
VPS28Vacuolar sorting-associated protein 28-like protein; Belongs to the VPS28 family. (864 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform B. (524 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (191 aa)
AV530_014524Protein kinase domain-containing protein. (220 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1 isoform C. (959 aa)
AV530_010210Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (282 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (338 aa)
DFNA5Non-syndromic hearing impairment protein 5. (482 aa)
AV530_004854Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (946 aa)
FOSProto-oncogene c-Fos. (367 aa)
LRRC74ALeucine-rich repeat-containing protein 74A isoform A. (500 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (492 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
AV530_002806Uncharacterized protein. (141 aa)
MAPK10Mitogen-activated protein kinase. (540 aa)
AV530_007822Toll-like receptor 2 type-2. (229 aa)
UBE2D3Ubiquitin-conjugating enzyme E2 D3 isoform B; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform B. (1044 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (581 aa)
AV530_015360Protein kinase domain-containing protein. (145 aa)
FGGFibrinogen gamma chain. (436 aa)
TLR2BToll-like receptor 2 type-2. (126 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
AV530_000672Toll-like receptor 2. (865 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (381 aa)
DNM1Dynamin-1 isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (861 aa)
TLR4Toll-like receptor 4. (829 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform B. (949 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (252 aa)
BIRC2Baculoviral IAP repeat-containing protein 2 isoform A. (608 aa)
TBK1Serine/threonine-protein kinase TBK1. (729 aa)
IKBIPInhibitor of nuclear factor kappa-B kinase-interacting protein. (310 aa)
TLR7Toll-like receptor 7 isoform C; Belongs to the Toll-like receptor family. (1411 aa)
RPS6KA3Ribosomal protein S6 kinase. (741 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (306 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform A. (385 aa)
LY96Lymphocyte antigen 96 isoform B. (136 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (757 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (934 aa)
AV530_015988Uncharacterized protein. (195 aa)
AV530_007050CD209 antigen-like protein C. (353 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (311 aa)
AV530_018033Bactericidal permeability-increasing protein. (477 aa)
BPIBactericidal permeability-increasing protein. (503 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (178 aa)
AV530_015989Pulmonary surfactant-associated protein A. (222 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (666 aa)
LRRC34Leucine-rich repeat-containing protein 34 isoform A. (472 aa)
LRRC31Leucine-rich repeat-containing protein 31. (582 aa)
AV530_009231TIR domain-containing protein. (235 aa)
AV530_009252Protein MRP-126; Belongs to the S-100 family. (116 aa)
AV530_009234Uncharacterized protein. (651 aa)
EEA1Early endosome antigen 1 isoform B. (1489 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
AV530_017334Toll-like receptor. (402 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (918 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2 isoform A. (728 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (880 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
UNC93AUnc-93-like protein A. (458 aa)
FOSL2Fos-related antigen 2. (323 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (410 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform B. (620 aa)
APOBApolipoprotein B-100. (4630 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (409 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform isoform A. (474 aa)
N4BP1NEDD4-binding protein 1. (265 aa)
MAPK15Mitogen-activated protein kinase 15. (498 aa)
AV530_013995Uncharacterized protein. (138 aa)
AV530_011288Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (267 aa)
TRAF2TNF receptor-associated factor. (472 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1 isoform A. (1375 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3 isoform B; Belongs to the protein kinase superfamily. (348 aa)
AV530_001035Uncharacterized protein. (1065 aa)
VRK3Inactive serine/threonine-protein kinase VRK3. (305 aa)
AV530_001177Vitellogenin domain-containing protein. (2791 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (219 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (291 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial-like. (136 aa)
FNBP4Formin-binding protein 4 isoform B. (995 aa)
AV530_013981ANK_REP_REGION domain-containing protein. (66 aa)
IRF7Interferon regulatory factor 7. (490 aa)
AV530_013269Serum amyloid A protein-like. (202 aa)
UNC93B1Unc-93-like protein B1. (646 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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