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POLR2J POLR2J FGF16 FGF16 AV530_006995 AV530_006995 AV530_003752 AV530_003752 AV530_003606 AV530_003606 PTBP3 PTBP3 NRAS NRAS FRS3 FRS3 CSDE1 CSDE1 GRB2 GRB2 FGFR4 FGFR4 FGF1 FGF1 FGF10 FGF10 AV530_006857 AV530_006857 PTBP1 PTBP1 POLR2E POLR2E FGF22 FGF22 AV530_011288 AV530_011288 FGF17 FGF17 FGF8 FGF8 TIAL1 TIAL1 FGFR2 FGFR2 AV530_004577 AV530_004577 AV530_004578 AV530_004578 AV530_004579 AV530_004579 POLR2K POLR2K ESRP1 ESRP1 AV530_013971 AV530_013971 SPRED1 SPRED1 KL KL FLRT2 FLRT2 FGF9 FGF9 BRAF BRAF FGF23 FGF23 FGF6 FGF6 FRS2 FRS2 POLR2D POLR2D AV530_005013 AV530_005013 PIK3CA PIK3CA POLR2H POLR2H FNDC3B FNDC3B UBC UBC ESRP2 ESRP2 COQ9 COQ9 AV530_017637 AV530_017637 AV530_009482 AV530_009482 HNRNPM HNRNPM SHC1 SHC1 PTBP2 PTBP2 MKNK1 MKNK1 STIL STIL FGF18 FGF18 FGF5 FGF5 FGF2 FGF2 GAB1 GAB1 PTPN11 PTPN11 POLR2B POLR2B FGF3 FGF3 FGF19 FGF19 FGF4 FGF4 HRAS HRAS POLR2L POLR2L FGFBP2 FGFBP2 SPRED2 SPRED2 SOS1 SOS1 RPS27A RPS27A FLRT3 FLRT3 AV530_004421 AV530_004421 SPRY2 SPRY2 GTF2F2 GTF2F2 FNDC3A FNDC3A NCBP1 NCBP1 CBL CBL RBFOX2 RBFOX2 POLR2F POLR2F AV530_009181 AV530_009181 ANOS1 ANOS1 KRAS KRAS FGFRL1 FGFRL1 FGFR3 FGFR3 FGFBP1 FGFBP1 KLB KLB FGF20 FGF20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
AV530_006995LRRNT domain-containing protein. (848 aa)
AV530_003752Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa)
AV530_003606Fibronectin type-III domain-containing protein 3a-like. (1166 aa)
PTBP3Polypyrimidine tract-binding protein 3. (451 aa)
NRASGTPase NRas. (189 aa)
FRS3Fibroblast growth factor receptor substrate 3. (533 aa)
CSDE1Cold shock domain-containing protein E1. (1129 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
FGFR4Fibroblast growth factor receptor 4. (1092 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (161 aa)
AV530_006857Protein kinase domain-containing protein. (217 aa)
PTBP1Polypyrimidine tract-binding protein 1 isoform B. (561 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (121 aa)
AV530_011288Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
TIAL1Nucleolysin TIAR isoform A. (388 aa)
FGFR2Fibroblast growth factor receptor. (915 aa)
AV530_004577Uncharacterized protein. (414 aa)
AV530_004578Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (247 aa)
AV530_004579Protein kinase domain-containing protein. (145 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (128 aa)
ESRP1Epithelial splicing regulatory protein 1 isoform B. (733 aa)
AV530_013971RNA_pol_Rpb1_7 domain-containing protein. (101 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (414 aa)
KLKlotho isoform B. (992 aa)
FLRT2Leucine-rich repeat transmembrane protein FLRT2. (662 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
BRAFSerine/threonine-protein kinase B-raf isoform A. (769 aa)
FGF23Fibroblast growth factor 23. (181 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FRS2Fibroblast growth factor receptor substrate 2. (510 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
AV530_005013Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (157 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
ESRP2Epithelial splicing regulatory protein 2 isoform B. (917 aa)
COQ9Ubiquinone biosynthesis protein COQ9, mitochondrial. (634 aa)
AV530_017637RRM domain-containing protein. (91 aa)
AV530_009482Uncharacterized protein. (237 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M isoform A. (483 aa)
SHC1SHC-transforming protein 1. (323 aa)
PTBP2Polypyrimidine tract-binding protein 2 isoform B. (589 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (412 aa)
STILSCL-interrupting locus protein. (1018 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
GAB1GRB2-associated-binding protein 1 isoform A. (721 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (581 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (231 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
HRASGTPase HRas. (184 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
FGFBP2Fibroblast growth factor-binding protein 2. (209 aa)
SPRED2Sprouty-related, EVH1 domain-containing protein 2. (419 aa)
SOS1Son of sevenless-like protein 1. (1345 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (675 aa)
AV530_004421Uncharacterized protein. (606 aa)
SPRY2Sprouty-like protein 2. (313 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (262 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1176 aa)
NCBP1Nuclear cap-binding protein subunit 1. (791 aa)
CBLE3 ubiquitin-protein ligase CBL. (903 aa)
RBFOX2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (393 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
AV530_009181PID domain-containing protein. (305 aa)
ANOS1Anosmin-1. (677 aa)
KRASGTPase KRas isoform A. (192 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (528 aa)
FGFR3Fibroblast growth factor receptor. (829 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (297 aa)
KLBBeta-klotho. (961 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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