STRINGSTRING
AV530_002602 AV530_002602 CTNNB1 CTNNB1 AV530_010705 AV530_010705 LGR5 LGR5 LRP6 LRP6 DACT1 DACT1 WNT5A WNT5A AKT1 AKT1 PSMC1 PSMC1 AV530_011467 AV530_011467 TLE1 TLE1 KLHL12 KLHL12 LGR6 LGR6 WNT3A WNT3A SLC39A13 SLC39A13 TLE4 TLE4 AV530_007002 AV530_007002 PIP5K1B PIP5K1B YWHAZ YWHAZ AV530_006594 AV530_006594 DBNL DBNL LEO1 LEO1 USP8 USP8 PYGO1 PYGO1 CTBP1 CTBP1 SOX5 SOX5 AV530_008896 AV530_008896 AV530_018631 AV530_018631 SOX4 SOX4 AV530_008416 AV530_008416 RSPO1 RSPO1 AV530_009290 AV530_009290 RUVBL1 RUVBL1 APC APC AV530_012300 AV530_012300 RNF146 RNF146 RSPO3 RSPO3 SOX11 SOX11 LRP5 LRP5 SOX6 SOX6 PSMA1 PSMA1 LGR4 LGR4 FZD4 FZD4 KAT7 KAT7 ZNRF3 ZNRF3 KREMEN1 KREMEN1 TNKS TNKS SFRP2 SFRP2 DKK2 DKK2 LEF1 LEF1 AV530_019789 AV530_019789 AV530_002806 AV530_002806 PPP2R1A PPP2R1A HECW1 HECW1 WNT1 WNT1 CDC73 CDC73 AV530_008744 AV530_008744 AV530_008745 AV530_008745 RNF43 RNF43 AV530_006927 AV530_006927 CSNK2A2 CSNK2A2 UBC UBC AV530_000007 AV530_000007 PSMD11 PSMD11 AV530_012178 AV530_012178 DVL3 DVL3 DKK1 DKK1 CUL3 CUL3 SFRP1 SFRP1 TCF7L2 TCF7L2 SFRP5 SFRP5 BTRC BTRC TNKS2 TNKS2 WNT8B WNT8B PSMA7 PSMA7 AV530_018028 AV530_018028 CSNK2A1 CSNK2A1 SOX18 SOX18 RSPO4 RSPO4 FZD8 FZD8 PSMD1 PSMD1 DVL1 DVL1 CTNNBIP1 CTNNBIP1 WNT3 WNT3 AV530_006701 AV530_006701 AV530_006703 AV530_006703 APC2 APC2 KXD1 KXD1 RYK RYK SOX21 SOX21 AV530_006702 AV530_006702 TRRAP TRRAP SOX8 SOX8 CREBBP CREBBP AV530_001106 AV530_001106 AXIN1 AXIN1 SOX30 SOX30 WNT8A WNT8A HMGXB3 HMGXB3 SOX9 SOX9 AXIN2 AXIN2 SMURF2 SMURF2 TCF7 TCF7 AV530_019053 AV530_019053 AV530_003671 AV530_003671 PSMD10 PSMD10 XIAP XIAP AV530_000283 AV530_000283 FZD5 FZD5 AV530_014876 AV530_014876 WIF1 WIF1 TLE3 TLE3 GSK3B GSK3B RBX1 RBX1 SOX10 SOX10 CAV1 CAV1 EP300 EP300 AV530_013083 AV530_013083 AV530_013014 AV530_013014 AV530_012974 AV530_012974 CBY1 CBY1 USP34 USP34 RPS27A RPS27A PSME4 PSME4 XPO1 XPO1 BCL9 BCL9 SOX1 SOX1 SOX7 SOX7 AV530_014703 AV530_014703 ZBTB44 ZBTB44 AV530_013811 AV530_013811 BCL9L BCL9L TERT TERT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AV530_002602Putative methyltransferase DDB G0268948. (367 aa)
CTNNB1Catenin beta-1. (748 aa)
AV530_010705Uncharacterized protein. (69 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5. (787 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1596 aa)
DACT1Dapper-like protein 1 isoform C. (865 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
AV530_011467Uncharacterized protein. (203 aa)
TLE1Transducin-like enhancer protein 1. (772 aa)
KLHL12Kelch-like protein 12. (565 aa)
LGR6Leucine-rich repeat-containing G-protein coupled receptor 6 isoform A. (956 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
SLC39A13Zinc transporter ZIP13. (330 aa)
TLE4Transducin-like enhancer protein 4 isoform B. (863 aa)
AV530_007002Uncharacterized protein. (77 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta. (540 aa)
YWHAZ14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (373 aa)
AV530_006594R-spondin-2. (241 aa)
DBNLDrebrin-like protein. (636 aa)
LEO1RNA polymerase-associated protein LEO1. (656 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform A; Belongs to the peptidase C19 family. (1121 aa)
PYGO1Pygopus-like protein 1. (409 aa)
CTBP1C-terminal-binding protein 1 isoform C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (458 aa)
SOX5Transcription factor SOX-5 isoform A. (494 aa)
AV530_008896Uncharacterized protein. (290 aa)
AV530_018631Uncharacterized protein. (91 aa)
SOX4Transcription factor SOX-4. (164 aa)
AV530_008416Uncharacterized protein. (102 aa)
RSPO1R-spondin-1. (260 aa)
AV530_009290Secreted frizzled-related protein 5. (258 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
APCAdenomatous polyposis coli protein isoform B. (2850 aa)
AV530_01230026S protease regulatory subunit 6B-like. (85 aa)
RNF146E3 ubiquitin-protein ligase RNF146 isoform B. (445 aa)
RSPO3R-spondin-3. (275 aa)
SOX11Transcription factor SOX. (403 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1621 aa)
SOX6Transcription factor SOX-6 isoform B. (994 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (909 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (475 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
ZNRF3E3 ubiquitin-protein ligase ZNRF3. (926 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
TNKSPoly [ADP-ribose] polymerase. (1269 aa)
SFRP2Secreted frizzled-related protein 2. (292 aa)
DKK2Dickkopf-related protein 2. (270 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform A. (412 aa)
AV530_019789Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (227 aa)
AV530_002806Uncharacterized protein. (141 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform isoform A. (474 aa)
HECW1E3 ubiquitin-protein ligase HECW1 isoform A. (1602 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
CDC73Parafibromin. (531 aa)
AV530_008744Protein kinase domain-containing protein; Belongs to the membrane-bound acyltransferase family. (208 aa)
AV530_008745Protein kinase domain-containing protein; Belongs to the membrane-bound acyltransferase family. (388 aa)
RNF43E3 ubiquitin-protein ligase RNF43. (754 aa)
AV530_006927Pygopus-like protein 2. (415 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (366 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
AV530_000007Secreted frizzled-related protein 2. (286 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (544 aa)
AV530_012178Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (668 aa)
DVL3Segment polarity dishevelled-like protein DVL-3 isoform A. (736 aa)
DKK1Dickkopf-related protein 1. (130 aa)
CUL3Cullin-3; Belongs to the cullin family. (782 aa)
SFRP1Secreted frizzled-related protein 1. (301 aa)
TCF7L2Transcription factor 7-like 2 isoform C. (522 aa)
SFRP5Secreted frizzled-related protein 5. (316 aa)
BTRCF-box/WD repeat-containing protein 1A. (596 aa)
TNKS2Poly [ADP-ribose] polymerase. (1144 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
AV530_018028HMG box domain-containing protein. (258 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
SOX18Transcription factor SOX-18. (377 aa)
RSPO4R-spondin-4. (223 aa)
FZD8Frizzled-8 isoform A; Belongs to the G-protein coupled receptor Fz/Smo family. (507 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (944 aa)
DVL1Segment polarity dishevelled-like protein DVL-1 isoform A. (668 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (204 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
AV530_006701TLE_N domain-containing protein. (325 aa)
AV530_006703Transducin-like enhancer protein 1. (714 aa)
APC2Adenomatous polyposis coli protein 2; Belongs to the universal ribosomal protein uS19 family. (2562 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
RYKTyrosine-protein kinase RYK. (542 aa)
SOX21Transcription factor SOX-21. (240 aa)
AV530_006702Uncharacterized protein. (227 aa)
TRRAPTransformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3837 aa)
SOX8Transcription factor SOX-8 isoform A. (470 aa)
CREBBPCREB-binding protein isoform C. (2618 aa)
AV530_001106TAZ-type domain-containing protein. (473 aa)
AXIN1Axin-1. (841 aa)
SOX30Transcription factor SOX-30. (658 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
HMGXB3HMG domain-containing protein 3. (1353 aa)
SOX9Transcription factor SOX-9. (400 aa)
AXIN2Axin-2 isoform B. (829 aa)
SMURF2E3 ubiquitin-protein ligase. (753 aa)
TCF7Transcription factor 7 isoform A. (379 aa)
AV530_019053Transcription factor SOX-13. (691 aa)
AV530_003671Transcription factor SOX-3. (316 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
XIAPE3 ubiquitin-protein ligase XIAP isoform A. (574 aa)
AV530_000283Uncharacterized protein. (121 aa)
FZD5Frizzled-5 isoform B; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
AV530_014876CSN8_PSD8_EIF3K domain-containing protein. (75 aa)
WIF1Wnt inhibitory factor 1. (342 aa)
TLE3Transducin-like enhancer protein 3 isoform A. (779 aa)
GSK3BGlycogen synthase kinase-3 beta isoform B; Belongs to the protein kinase superfamily. (433 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
SOX10Transcription factor SOX-10. (498 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
EP300Histone acetyltransferase p300. (1778 aa)
AV530_013083Histone H2B; Belongs to the histone H2B family. (126 aa)
AV530_013014TAZ-type domain-containing protein. (591 aa)
AV530_012974Casein kinase I; Belongs to the protein kinase superfamily. (416 aa)
CBY1Chibby-like protein 1. (126 aa)
USP34Ubiquitin carboxyl-terminal hydrolase 34 isoform B; Belongs to the peptidase C19 family. (3600 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
PSME4Proteasome activator complex subunit 4 isoform A. (1824 aa)
XPO1Exportin-1. (999 aa)
BCL9B-cell CLL/lymphoma 9 protein isoform B. (1519 aa)
SOX1Transcription factor SOX-1 isoform B. (366 aa)
SOX7Transcription factor SOX-7. (288 aa)
AV530_014703Uncharacterized protein. (147 aa)
ZBTB44Zinc finger and BTB domain-containing protein 44 isoform B. (646 aa)
AV530_013811Uncharacterized protein. (378 aa)
BCL9LB-cell CLL/lymphoma 9-like protein. (1164 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1324 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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