STRINGSTRING
AV530_017950 AV530_017950 ABL1 ABL1 PSMD5 PSMD5 PSMB7 PSMB7 CKS2 CKS2 RB1 RB1 FNDC3A FNDC3A TFDP1 TFDP1 POLE POLE DYRK1A DYRK1A AV530_013845 AV530_013845 MCM8 MCM8 RPS27A RPS27A POLE3 POLE3 GMNN GMNN PPP4R1 PPP4R1 CKS1B CKS1B PSMD4 PSMD4 AV530_017918 AV530_017918 PPP2R3B PPP2R3B POLA1 POLA1 E2F2 E2F2 PRIM1 PRIM1 PSMA4 PSMA4 RBL1 RBL1 PSMB2 PSMB2 MCM2 MCM2 LIN9 LIN9 RPA2 RPA2 AV530_008472 AV530_008472 AV530_012300 AV530_012300 AKT3 AKT3 PSMB1 PSMB1 AV530_005533 AV530_005533 MCM9 MCM9 ORC3 ORC3 PRIM2 PRIM2 AV530_013250 AV530_013250 MCM3 MCM3 PSMA1 PSMA1 WEE1 WEE1 CCND1 CCND1 FNBP4 FNBP4 PSMD13 PSMD13 PSMC5 PSMC5 PSMB3 PSMB3 CDC6 CDC6 PSMD3 PSMD3 CREBZF CREBZF PSME3 PSME3 CDC45 CDC45 PSMD9 PSMD9 AV530_014700 AV530_014700 CCNH CCNH CCNA2 CCNA2 AV530_019789 AV530_019789 AV530_002806 AV530_002806 PPP2R1A PPP2R1A LIN54 LIN54 CUL1 CUL1 AV530_016196 AV530_016196 ORC2 ORC2 ORC1 ORC1 CDC7 CDC7 AV530_004707 AV530_004707 ORC5 ORC5 MCM10 MCM10 CCNE1 CCNE1 E2F4 E2F4 PSMD7 PSMD7 PSMC2 PSMC2 CDT1 CDT1 RBL2 RBL2 UBC UBC RPA1 RPA1 PSMD11 PSMD11 FNDC3B FNDC3B PSMD2 PSMD2 TFDP2 TFDP2 PPP2R3A PPP2R3A MCM6 MCM6 PSMD14 PSMD14 ORC4 ORC4 WEE2 WEE2 MCM5 MCM5 CCND2 CCND2 AV530_010935 AV530_010935 CDKN1B CDKN1B CCNA1 CCNA1 PSMD6 PSMD6 PSMC6 PSMC6 MNAT1 MNAT1 AKT1 AKT1 PPP4R4 PPP4R4 PSMC1 PSMC1 DBF4 DBF4 RPA3 RPA3 PSMA3 PSMA3 CDK6 CDK6 SKP2 SKP2 AV530_004854 AV530_004854 CDKN2C CDKN2C PSMC3 PSMC3 PPP2R3C PPP2R3C LIN52 LIN52 PSMA6 PSMA6 CABLES1 CABLES1 LYN LYN AV530_006325 AV530_006325 CCNE2 CCNE2 E2F5 E2F5 RBBP8NL RBBP8NL CABLES2 CABLES2 PSMF1 PSMF1 E2F1 E2F1 SRC SRC MYBL2 MYBL2 PSMD1 PSMD1 ORC6 ORC6 KXD1 KXD1 TM4SF19 TM4SF19 MEIOB MEIOB SKP1 SKP1 PSMD12 PSMD12 CDK3 CDK3 CCND3 CCND3 PSMA5 PSMA5 AV530_003606 AV530_003606 PSMD10 PSMD10 POLA2 POLA2 AV530_007135 AV530_007135 POLE2 POLE2 PSMA2 PSMA2 AV530_014876 AV530_014876 AV530_008697 AV530_008697 AV530_019914 AV530_019914 PSMB4 PSMB4 CDK7 CDK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AV530_017950Uncharacterized protein. (108 aa)
ABL1Tyrosine-protein kinase. (1195 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB7Proteasome subunit beta type-7. (181 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
RB1Retinoblastoma-associated protein isoform A. (1170 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1176 aa)
TFDP1Transcription factor. (412 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2276 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A. (758 aa)
AV530_013845DNA polymerase alpha subunit B-like. (354 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (822 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
POLE3DNA polymerase epsilon subunit 3. (171 aa)
GMNNGeminin isoform A. (282 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform B. (949 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (372 aa)
AV530_017918Uncharacterized protein. (74 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform B. (581 aa)
POLA1DNA polymerase. (1501 aa)
E2F2Transcription factor E2F2 isoform B. (349 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
RBL1Retinoblastoma-like protein 1 isoform A. (1050 aa)
PSMB2Proteasome subunit beta. (201 aa)
MCM2DNA helicase; Belongs to the MCM family. (887 aa)
LIN9Lin-9-like protein isoform B. (535 aa)
RPA2Replication protein A subunit. (271 aa)
AV530_008472Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (286 aa)
AV530_01230026S protease regulatory subunit 6B-like. (85 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PSMB1Proteasome subunit beta. (237 aa)
AV530_005533MCM domain-containing protein; Belongs to the MCM family. (413 aa)
MCM9DNA helicase MCM9. (744 aa)
ORC3Origin recognition complex subunit 3 isoform A. (716 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (561 aa)
AV530_013250Uncharacterized protein. (192 aa)
MCM3DNA helicase; Belongs to the MCM family. (811 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
WEE1Wee1-like protein kinase. (640 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
FNBP4Formin-binding protein 4 isoform B. (995 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (378 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (411 aa)
PSMB3Proteasome subunit beta. (205 aa)
CDC6Cell division control 6-like protein. (894 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (517 aa)
CREBZFCREB/ATF bZIP transcription factor. (195 aa)
PSME3Proteasome activator complex subunit 3. (254 aa)
CDC45Cell division control 45-like protein. (566 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (202 aa)
AV530_014700MCM_N domain-containing protein. (107 aa)
CCNHCyclin-H; Belongs to the cyclin family. (321 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (299 aa)
AV530_019789Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (227 aa)
AV530_002806Uncharacterized protein. (141 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform isoform A. (474 aa)
LIN54Lin-54-like protein isoform A. (832 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
AV530_016196LisH domain and HEAT repeat-containing KIAA1468-like protein. (1124 aa)
ORC2Origin recognition complex subunit 2. (569 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (856 aa)
CDC7Cell division cycle 7-related protein kinase. (634 aa)
AV530_004707CBFD_NFYB_HMF domain-containing protein. (70 aa)
ORC5Origin recognition complex subunit 5. (447 aa)
MCM10MCM10-like protein. (868 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (384 aa)
E2F4Transcription factor E2F4. (399 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (311 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
CDT1DNA replication factor Cdt1 isoform B. (543 aa)
RBL2Retinoblastoma-like protein 2. (1080 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (646 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (544 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
TFDP2Transcription factor. (447 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1143 aa)
MCM6DNA helicase; Belongs to the MCM family. (825 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (374 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
WEE2Wee1-like protein kinase. (560 aa)
MCM5DNA helicase; Belongs to the MCM family. (815 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (378 aa)
AV530_010935Cyclin-dependent kinase inhibitor 1. (100 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (238 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (387 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (384 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform B. (870 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
DBF4DBF4-like protein A. (707 aa)
RPA3Replication protein A subunit. (121 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (352 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
AV530_004854Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (946 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (148 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (422 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (450 aa)
LIN52Lin-52-like protein. (112 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CABLES1CDK5 and ABL1 enzyme substrate 1. (421 aa)
LYNTyrosine-protein kinase. (557 aa)
AV530_006325DNA helicase; Belongs to the MCM family. (1014 aa)
CCNE2G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (474 aa)
E2F5Transcription factor E2F5. (458 aa)
RBBP8NLRBBP8 N-terminal-like protein. (566 aa)
CABLES2CDK5 and ABL1 enzyme substrate 2 isoform C. (497 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
E2F1Transcription factor E2F1. (463 aa)
SRCTyrosine-protein kinase. (585 aa)
MYBL2Myb-related protein B. (676 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (944 aa)
ORC6Origin recognition complex subunit 6. (271 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
TM4SF19Transmembrane 4 L6 family member 19. (252 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform B. (493 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (219 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (309 aa)
CCND3G1/S-specific cyclin-D3; Belongs to the cyclin family. (292 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
AV530_003606Fibronectin type-III domain-containing protein 3a-like. (1166 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
POLA2DNA polymerase alpha subunit B-like. (220 aa)
AV530_007135DNA_pol_E_B domain-containing protein. (226 aa)
POLE2DNA polymerase epsilon subunit 2. (315 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
AV530_014876CSN8_PSD8_EIF3K domain-containing protein. (75 aa)
AV530_008697Protein kinase domain-containing protein. (86 aa)
AV530_019914Uncharacterized protein. (87 aa)
PSMB4Proteasome subunit beta type-4. (199 aa)
CDK7Cyclin-dependent kinase 7. (226 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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