37 items (Patagioenas fasciata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	FGF23	Fibroblast growth factor 23. (181 aa)
	BRAF	Serine/threonine-protein kinase B-raf isoform A. (769 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	FGF17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	AV530_011288	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	AV530_006857	Protein kinase domain-containing protein. (217 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	FGFR4	Fibroblast growth factor receptor 4. (1092 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CSDE1	Cold shock domain-containing protein E1. (1129 aa)
	FRS3	Fibroblast growth factor receptor substrate 3. (533 aa)
	NRAS	GTPase NRas. (189 aa)
	AV530_003606	Fibronectin type-III domain-containing protein 3a-like. (1166 aa)
	SOS1	Son of sevenless-like protein 1. (1345 aa)
	FGF16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (178 aa)
	SPRY2	Sprouty-like protein 2. (313 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1176 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (903 aa)
	AV530_009181	PID domain-containing protein. (305 aa)
	KRAS	GTPase KRas isoform A. (192 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa)
	HRAS	GTPase HRas. (184 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	FGF19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (581 aa)
	GAB1	GRB2-associated-binding protein 1 isoform A. (721 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	MKNK1	MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (412 aa)
	SHC1	SHC-transforming protein 1. (323 aa)
	UBC	Polyubiquitin-C isoform A. (365 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1208 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (510 aa)

Your Current Organism:

Patagioenas fasciata

NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AV530_003606	AV530_011288	A0A1V4KY83	A0A1V4KNV7	Fibronectin type-III domain-containing protein 3a-like.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.479
AV530_003606	PTPN11	A0A1V4KY83	A0A1V4JTE0	Fibronectin type-III domain-containing protein 3a-like.	Tyrosine-protein phosphatase non-receptor type 11.	0.479
AV530_003606	RPS27A	A0A1V4KY83	A0A1V4IG00	Fibronectin type-III domain-containing protein 3a-like.	Ubiquitin-40S ribosomal protein S27a.	0.431
AV530_006857	SPRY2	A0A1V4KQM0	A0A1V4J473	Protein kinase domain-containing protein.	Sprouty-like protein 2.	0.492
AV530_009181	AV530_011288	A0A1V4JAQ0	A0A1V4KNV7	PID domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.725
AV530_009181	BRAF	A0A1V4JAQ0	A0A1V4K999	PID domain-containing protein.	Serine/threonine-protein kinase B-raf isoform A.	0.409
AV530_009181	CBL	A0A1V4JAQ0	A0A1V4J7V6	PID domain-containing protein.	E3 ubiquitin-protein ligase CBL.	0.692
AV530_009181	CSDE1	A0A1V4JAQ0	A0A1V4KX13	PID domain-containing protein.	Cold shock domain-containing protein E1.	0.487
AV530_009181	FGF1	A0A1V4JAQ0	A0A1V4KU04	PID domain-containing protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.435
AV530_009181	FGF16	A0A1V4JAQ0	A0A1V4KZZ7	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.433
AV530_009181	FGF17	A0A1V4JAQ0	A0A1V4KJC8	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.408
AV530_009181	FGF18	A0A1V4JAQ0	A0A1V4JWD6	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.483
AV530_009181	FGF19	A0A1V4JAQ0	A0A1V4JPC3	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.430
AV530_009181	FGF2	A0A1V4JAQ0	A0A1V4JUL8	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.404
AV530_009181	FGF20	A0A1V4JAQ0	A0A1V4JG44	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.433
AV530_009181	FGF23	A0A1V4JAQ0	A0A1V4K8D8	PID domain-containing protein.	Fibroblast growth factor 23.	0.430
AV530_009181	FGF4	A0A1V4JAQ0	A0A1V4JPB6	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.430
AV530_009181	FGF8	A0A1V4JAQ0	A0A1V4KIW7	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
AV530_009181	FGF9	A0A1V4JAQ0	A0A1V4K9J9	PID domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.433
AV530_009181	FGFR4	A0A1V4JAQ0	A0A1V4KU49	PID domain-containing protein.	Fibroblast growth factor receptor 4.	0.834