STRINGSTRING
AV530_013940 AV530_013940 AV530_019426 AV530_019426 SMAD3 SMAD3 USP3 USP3 AV530_002822 AV530_002822 USP5 USP5 AV530_011576 AV530_011576 AV530_007773 AV530_007773 AV530_007772 AV530_007772 AV530_013085 AV530_013085 AV530_007771 AV530_007771 AV530_013083 AV530_013083 USP15 USP15 AV530_013074 AV530_013074 BIRC2 BIRC2 CFTR CFTR USP28 USP28 USP2 USP2 USP20 USP20 GPR21 GPR21 DDX58 DDX58 TOMM70A TOMM70A USP25 USP25 USP16 USP16 PSME4 PSME4 USP34 USP34 RPS27A RPS27A AV530_002466 AV530_002466 AV530_002465 AV530_002465 MDM2 MDM2 USP18 USP18 SMAD7 SMAD7 AV530_004178 AV530_004178 RNF123 RNF123 USP4 USP4 ATXN7 ATXN7 CCNA1 CCNA1 AV530_012142 AV530_012142 USP12 USP12 WDR20 WDR20 PSMC1 PSMC1 SKP2 SKP2 NPEPL1 NPEPL1 DDB2 DDB2 ZFYVE19 ZFYVE19 ZFYVE1 ZFYVE1 AV530_010565 AV530_010565 AV530_013183 AV530_013183 TRAF6 TRAF6 POLB POLB IDE IDE VDAC3 VDAC3 TNKS2 TNKS2 VDAC2 VDAC2 ADRM1 ADRM1 BIRC7 BIRC7 PSMA7 PSMA7 WDR48 WDR48 PSMD1 PSMD1 CCP110 CCP110 KLHL17 KLHL17 MUL1 MUL1 HSPG2 HSPG2 TRAF2 TRAF2 AV530_014730 AV530_014730 KXD1 KXD1 FKBP8 FKBP8 AV530_008875 AV530_008875 AV530_006208 AV530_006208 AV530_018590 AV530_018590 USP42 USP42 USP22 USP22 USP7 USP7 AXIN1 AXIN1 ADRB2 ADRB2 UBLCP1 UBLCP1 MAT2B MAT2B VDAC1 VDAC1 AV530_019227 AV530_019227 MYC MYC USP36 USP36 AXIN2 AXIN2 SMURF2 SMURF2 AV530_016330 AV530_016330 AV530_016331 AV530_016331 USP49 USP49 MDM4 MDM4 AV530_008413 AV530_008413 AR AR ARR3 ARR3 SNX12 SNX12 AV530_003757 AV530_003757 RNF128 RNF128 PSMD10 PSMD10 AV530_003906 AV530_003906 AV530_014876 AV530_014876 AV530_019914 AV530_019914 IFIH1 IFIH1 USP37 USP37 STAM2 STAM2 USP13 USP13 SMAD4 SMAD4 PTEN PTEN PSMD11 PSMD11 UBC UBC PTRH2 PTRH2 CYLD CYLD USP32 USP32 USP10 USP10 AV530_017677 AV530_017677 ATXN7L1 ATXN7L1 AV530_000036 AV530_000036 USP33 USP33 USP24 USP24 NRD1 NRD1 CDC20 CDC20 TGFBR1 TGFBR1 SMAD1 SMAD1 CCNA2 CCNA2 MTFP1 MTFP1 RNF13 RNF13 TNKS TNKS USP30 USP30 UFD1L UFD1L BECN1 BECN1 PSMC5 PSMC5 AV530_016389 AV530_016389 USP47 USP47 PSMA1 PSMA1 MAP3K7 MAP3K7 SNX3 SNX3 RNF146 RNF146 TOMM20 TOMM20 AV530_012300 AV530_012300 RUVBL1 RUVBL1 TADA3 TADA3 USP19 USP19 AV530_008416 AV530_008416 CLSPN CLSPN AV530_017808 AV530_017808 USP46 USP46 LAP3 LAP3 TADA2B TADA2B AV530_000729 AV530_000729 USP8 USP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AV530_013940Ubiquitinyl hydrolase 1. (520 aa)
AV530_019426Peptidylprolyl isomerase. (404 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
USP3Ubiquitin carboxyl-terminal hydrolase. (524 aa)
AV530_002822WD_REPEATS_REGION domain-containing protein. (301 aa)
USP5Ubiquitin carboxyl-terminal hydrolase. (832 aa)
AV530_011576BTB domain-containing protein. (240 aa)
AV530_007773MH1 domain-containing protein. (284 aa)
AV530_007772MH2 domain-containing protein. (174 aa)
AV530_013085Histone H2B; Belongs to the histone H2B family. (126 aa)
AV530_007771MH2 domain-containing protein. (141 aa)
AV530_013083Histone H2B; Belongs to the histone H2B family. (126 aa)
USP15Ubiquitin carboxyl-terminal hydrolase. (981 aa)
AV530_013074Histone H2B; Belongs to the histone H2B family. (126 aa)
BIRC2Baculoviral IAP repeat-containing protein 2 isoform A. (608 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
USP28Ubiquitin carboxyl-terminal hydrolase 28 isoform A; Belongs to the peptidase C19 family. (1237 aa)
USP2Ubiquitin carboxyl-terminal hydrolase. (589 aa)
USP20Ubiquitin carboxyl-terminal hydrolase. (977 aa)
GPR21Putative G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (348 aa)
DDX58Putative ATP-dependent RNA helicase DDX58. (884 aa)
TOMM70AMitochondrial import receptor subunit TOM70. (583 aa)
USP25Ubiquitin carboxyl-terminal hydrolase 25 isoform A; Belongs to the peptidase C19 family. (1077 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (831 aa)
PSME4Proteasome activator complex subunit 4 isoform A. (1824 aa)
USP34Ubiquitin carboxyl-terminal hydrolase 34 isoform B; Belongs to the peptidase C19 family. (3600 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
AV530_002466SAM domain-containing protein. (436 aa)
AV530_002465Mitogen-activated protein kinase kinase kinase MLT. (450 aa)
MDM2E3 ubiquitin-protein ligase Mdm2 isoform B. (542 aa)
USP18Ubiquitin carboxyl-terminal hydrolase. (417 aa)
SMAD7Mothers against decapentaplegic-like protein 7. (181 aa)
AV530_004178RING-type domain-containing protein. (146 aa)
RNF123E3 ubiquitin-protein ligase RNF123. (1421 aa)
USP4Ubiquitin carboxyl-terminal hydrolase. (942 aa)
ATXN7Ataxin-7. (811 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (387 aa)
AV530_012142Ubiquitin thioesterase OTUB1. (71 aa)
USP12Ubiquitin carboxyl-terminal hydrolase 12; Belongs to the peptidase C19 family. (369 aa)
WDR20WD repeat-containing protein 20. (592 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
NPEPL1Putative aminopeptidase NPEPL1. (523 aa)
DDB2DNA damage-binding protein 2 isoform B. (516 aa)
ZFYVE19Abscission/NoCut checkpoint regulator isoform B. (500 aa)
ZFYVE1Zinc finger FYVE domain-containing protein 1. (701 aa)
AV530_010565Methyltransf_11 domain-containing protein. (301 aa)
AV530_013183Beta-arrestin-1. (336 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
IDEInsulin-degrading enzyme; Belongs to the peptidase M16 family. (1024 aa)
VDAC3Voltage-dependent anion-selective channel protein 3. (296 aa)
TNKS2Poly [ADP-ribose] polymerase. (1144 aa)
VDAC2Voltage-dependent anion-selective channel protein 2. (440 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1. (376 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (311 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
WDR48WD repeat-containing protein 48. (499 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (944 aa)
CCP110Centriolar coiled-coil protein of isoform A. (1018 aa)
KLHL17Kelch-like protein 17. (534 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein isoform B; Belongs to the peptidase C19 family. (2698 aa)
TRAF2TNF receptor-associated factor. (472 aa)
AV530_014730MH1 domain-containing protein. (90 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
FKBP8Peptidylprolyl isomerase. (408 aa)
AV530_008875Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (749 aa)
AV530_006208USP domain-containing protein; Belongs to the peptidase C19 family. (355 aa)
AV530_018590Histone H2B; Belongs to the histone H2B family. (126 aa)
USP42Ubiquitin carboxyl-terminal hydrolase 42; Belongs to the peptidase C19 family. (1346 aa)
USP22Ubiquitin carboxyl-terminal hydrolase. (525 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1103 aa)
AXIN1Axin-1. (841 aa)
ADRB2Beta-2 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa)
UBLCP1Ubiquitin-like domain-containing CTD phosphatase 1. (318 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (349 aa)
AV530_019227Uncharacterized protein. (75 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (432 aa)
USP36Ubiquitin carboxyl-terminal hydrolase 36 isoform B; Belongs to the peptidase C19 family. (1076 aa)
AXIN2Axin-2 isoform B. (829 aa)
SMURF2E3 ubiquitin-protein ligase. (753 aa)
AV530_016330RING-type domain-containing protein. (279 aa)
AV530_016331E3 ubiquitin-protein ligase RNF13. (331 aa)
USP49Ubiquitin carboxyl-terminal hydrolase. (631 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (474 aa)
AV530_008413Uncharacterized protein. (724 aa)
ARAndrogen receptor. (655 aa)
ARR3Arrestin-C. (352 aa)
SNX12Sorting nexin-12. (162 aa)
AV530_003757Fork-head domain-containing protein. (135 aa)
RNF128E3 ubiquitin-protein ligase RNF128. (274 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
AV530_003906Ubiquitin specific peptidase 12-like; Belongs to the peptidase C19 family. (369 aa)
AV530_014876CSN8_PSD8_EIF3K domain-containing protein. (75 aa)
AV530_019914Uncharacterized protein. (87 aa)
IFIH1Interferon-induced helicase C domain-containing protein 1. (1010 aa)
USP37Ubiquitin carboxyl-terminal hydrolase. (988 aa)
STAM2Signal transducing adapter molecule 2. (520 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (848 aa)
SMAD4Mothers against decapentaplegic homolog. (362 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (389 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (544 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
PTRH2Peptidyl-tRNA hydrolase 2, mitochondrial. (234 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform B; Belongs to the peptidase C19 family. (954 aa)
USP32Ubiquitin carboxyl-terminal hydrolase 32 isoform B; Belongs to the peptidase C19 family. (1803 aa)
USP10Ubiquitin carboxyl-terminal hydrolase. (789 aa)
AV530_017677Uncharacterized protein. (199 aa)
ATXN7L1Ataxin-7-like protein 1 isoform B. (836 aa)
AV530_000036Histone H2B; Belongs to the histone H2B family. (180 aa)
USP33Ubiquitin carboxyl-terminal hydrolase. (911 aa)
USP24Ubiquitin carboxyl-terminal hydrolase 24 isoform B; Belongs to the peptidase C19 family. (2551 aa)
NRD1Nardilysin; Belongs to the peptidase M16 family. (1156 aa)
CDC20Cell division cycle 20-like protein isoform A. (505 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (299 aa)
MTFP1Mitochondrial fission process protein 1. (162 aa)
RNF13E3 ubiquitin-protein ligase RNF13. (381 aa)
TNKSPoly [ADP-ribose] polymerase. (1269 aa)
USP30Ubiquitin carboxyl-terminal hydrolase. (435 aa)
UFD1LUbiquitin fusion degradation 1-like protein. (307 aa)
BECN1Beclin-1. (448 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (411 aa)
AV530_016389Uncharacterized protein. (81 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform A; Belongs to the peptidase C19 family. (1375 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform B. (620 aa)
SNX3Sorting nexin-3. (162 aa)
RNF146E3 ubiquitin-protein ligase RNF146 isoform B. (445 aa)
TOMM20Mitochondrial import receptor subunit TOM20-like protein. (146 aa)
AV530_01230026S protease regulatory subunit 6B-like. (85 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
TADA3Transcriptional adapter 3. (432 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19 isoform C. (1384 aa)
AV530_008416Uncharacterized protein. (102 aa)
CLSPNClaspin isoform A. (1258 aa)
AV530_017808Ubiquitin carboxyl-terminal hydrolase. (587 aa)
USP46Ubiquitin carboxyl-terminal hydrolase 46; Belongs to the peptidase C19 family. (366 aa)
LAP3Cytosol aminopeptidase. (529 aa)
TADA2BTranscriptional adapter. (420 aa)
AV530_000729Histone H2B; Belongs to the histone H2B family. (123 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform A; Belongs to the peptidase C19 family. (1121 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
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