STRINGSTRING
VWA5B2 VWA5B2 CDK7 CDK7 AV530_008697 AV530_008697 AV530_017641 AV530_017641 AV530_017627 AV530_017627 GTF2H4 GTF2H4 AV530_003887 AV530_003887 AV530_003886 AV530_003886 KCTD2 KCTD2 SUMO2 SUMO2 AV530_016344 AV530_016344 UBE2I UBE2I MEIOB MEIOB KXD1 KXD1 UBE2N UBE2N UBE2V2 UBE2V2 DDB2 DDB2 RPA3 RPA3 MNAT1 MNAT1 AV530_014737 AV530_014737 PARP3 PARP3 ERCC3 ERCC3 RPA1 RPA1 UBC UBC SUMO1 SUMO1 ERCC2 ERCC2 CETN3 CETN3 CCNH CCNH AV530_010142 AV530_010142 GTF2H3 GTF2H3 DDB1 DDB1 GTF2H1 GTF2H1 USP45 USP45 GTF2H5 GTF2H5 RPA2 RPA2 PARP1 PARP1 XPC XPC PIAS1 PIAS1 RNF111 RNF111 VTCN1 VTCN1 RBX1 RBX1 NAIP NAIP XPA XPA ERCC5 ERCC5 CHD1L CHD1L CUL4A CUL4A RAD23B RAD23B RPS27A RPS27A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA5B2Von Willebrand factor A domain-containing protein 5B2. (1106 aa)
CDK7Cyclin-dependent kinase 7. (226 aa)
AV530_008697Protein kinase domain-containing protein. (86 aa)
AV530_017641HELICc2 domain-containing protein. (68 aa)
AV530_017627UBA domain-containing protein. (117 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (320 aa)
AV530_003887CULLIN_2 domain-containing protein; Belongs to the cullin family. (614 aa)
AV530_003886Cullin domain-containing protein; Belongs to the cullin family. (200 aa)
KCTD2BTB/POZ domain-containing protein KCTD2 isoform A. (309 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
AV530_016344Von Willebrand factor A domain-containing protein 5A-like. (757 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform B. (493 aa)
KXD1KxDL motif-containing protein 1. (190 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (144 aa)
DDB2DNA damage-binding protein 2 isoform B. (516 aa)
RPA3Replication protein A subunit. (121 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
AV530_014737HELICc2 domain-containing protein. (147 aa)
PARP3Poly [ADP-ribose] polymerase. (180 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (646 aa)
UBCPolyubiquitin-C isoform A. (365 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (198 aa)
CETN3Centrin-3. (167 aa)
CCNHCyclin-H; Belongs to the cyclin family. (321 aa)
AV530_010142Small ubiquitin-related modifier. (102 aa)
GTF2H3General transcription factor IIH subunit 3. (307 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
GTF2H1General transcription factor IIH subunit 1. (581 aa)
USP45Ubiquitin carboxyl-terminal hydrolase. (818 aa)
GTF2H5General transcription factor IIH subunit 5. (103 aa)
RPA2Replication protein A subunit. (271 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
XPCDNA repair protein complementing XP-C cells. (959 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (651 aa)
RNF111E3 ubiquitin-protein ligase Arkadia isoform A. (1051 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1. (79 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
NAIPBaculoviral IAP repeat-containing protein 1. (1198 aa)
XPADNA repair protein complementing XP-A cells. (180 aa)
ERCC5DNA repair protein complementing XP-G cells. (1128 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (887 aa)
CUL4ACullin-4A; Belongs to the cullin family. (770 aa)
RAD23BUV excision repair RAD23-like protein B. (400 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (178 aa)
Your Current Organism:
Patagioenas fasciata
NCBI taxonomy Id: 372326
Other names: P. fasciata monilis, Patagioenas fasciata monilis
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.